Page last updated: 2024-11-04

rofecoxib and Nerve Pain

rofecoxib has been researched along with Nerve Pain in 3 studies

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to examine the regulation of COX-2 in the rat SNI model and to evaluate the effectiveness of the selective COX-2 inhibitor rofecoxib in preventing neuropathic allodynia and hyperalgesia."3.72Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain. ( Broom, DC; Geisslinger, G; Kohno, T; Samad, TA; Tegeder, I; Woolf, CJ, 2004)
" Chronic administration of naproxen (3, 10 or 30 mg/kg), but not rofecoxib (1, 3 or 10 mg/kg), 2 h before, daily for 7 days, after nerve injury significantly attenuated and further delayed the development of hypersensitivity for 21 days following nerve injury."1.32Differential effects of naproxen and rofecoxib on the development of hypersensitivity following nerve injury in rats. ( Kulkarni, SK; Padi, SS, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Broom, DC1
Samad, TA1
Kohno, T1
Tegeder, I1
Geisslinger, G1
Woolf, CJ1
Padi, SS1
Kulkarni, SK1
Dudhgaonkar, SP1
Tandan, SK1
Kumar, D1
Naik, AK1
Raviprakash, V1

Other Studies

3 other studies available for rofecoxib and Nerve Pain

ArticleYear
Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain.
    Neuroscience, 2004, Volume: 124, Issue:4

    Topics: Animals; Behavior, Animal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors;

2004
Differential effects of naproxen and rofecoxib on the development of hypersensitivity following nerve injury in rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Hyperalgesia; Injections, Intraperitoneal; Lactones; Male; Napro

2004
Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
    European journal of pain (London, England), 2007, Volume: 11, Issue:5

    Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

2007