Page last updated: 2024-11-04

rofecoxib and Neoplasms

rofecoxib has been researched along with Neoplasms in 20 studies

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Fifty patients with advanced solid tumors were enrolled in this phase II trial, 43 of whom had received at least one prior chemotherapy regimen."2.72Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors. ( Cano, PO; Germond, CJ; Lopez, PG; Noble, JC; Whissell, M; Young, SD, 2006)
"Neoplastic fever is relatively common in cancer patients."2.71Cyclo-oxygenase II inhibitors in the treatment of neoplastic fever. ( Kathula, SK; Koduri, J; Polenakovik, H; Shah, K, 2003)
"Among the most widely prescribed drugs worldwide, non-steroidal anti-inflammatory drugs (NSAIDs) are effective for relieving pain, but they are also associated with a high incidence of gastrointestinal (GI) adverse events."2.41Do selective cyclo-oxygenase inhibitors eliminate the adverse events associated with nonsteroidal anti-inflammatory drug therapy? ( Devière, J, 2002)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's16 (80.00)29.6817
2010's1 (5.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Xie, L1
Li, R1
Zheng, B1
Xie, Z1
Fang, X1
Dai, T1
Wang, X2
Li, L1
Wang, L1
Cuny, GD1
Eriksen, J1
Tu, D1
Chen, Z1
Chen, X1
Hu, M1
Pereira, SAP1
Bobbink, FD1
Dyson, PJ1
Saraiva, MLMFS1
Devière, J1
Kathula, SK1
Shah, K1
Polenakovik, H1
Koduri, J1
Gehrmann, M1
Brunner, M1
Pfister, K1
Reichle, A1
Kremmer, E1
Multhoff, G1
Gately, S1
Li, WW1
Jayr, C2
Vanchieri, C2
Couzin, J1
Kamen, B1
Kieran, M1
Senior, K1
Rigas, B1
Kashfi, K1
Young, SD1
Whissell, M1
Noble, JC1
Cano, PO1
Lopez, PG1
Germond, CJ1
Grösch, S1
Maier, TJ1
Schiffmann, S1
Geisslinger, G1
Ziegler, J1
Dicker, AP1
Williams, TL1
Grant, DS1
Sharma, RA1

Reviews

8 reviews available for rofecoxib and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Do selective cyclo-oxygenase inhibitors eliminate the adverse events associated with nonsteroidal anti-inflammatory drug therapy?
    European journal of gastroenterology & hepatology, 2002, Volume: 14 Suppl 1

    Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Hu

2002
Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy.
    Seminars in oncology, 2004, Volume: 31, Issue:2 Suppl 7

    Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Celecoxib; Cell Movement; Cyclooxygenase

2004
[Analgesic effects of cyclooxygenase 2 inhibitors].
    Bulletin du cancer, 2004, Volume: 91 Spec No

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chronic Disease; Cycl

2004
Cancer prevention: a new era beyond cyclooxygenase-2.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc

2005
[Analgesic effects of cyclooxygenase 2 inhibitors].
    Bulletin du cancer, 2004, Volume: 91 Suppl 2

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Female; H

2004
Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors.
    Journal of the National Cancer Institute, 2006, Jun-07, Volume: 98, Issue:11

    Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Anti-Inflammatory Agents, N

2006
Translational medicine: targetting cyclo-oxygenase isozymes to prevent cancer.
    QJM : monthly journal of the Association of Physicians, 2002, Volume: 95, Issue:5

    Topics: Arachidonic Acid; Aspirin; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; C

2002

Trials

2 trials available for rofecoxib and Neoplasms

ArticleYear
Cyclo-oxygenase II inhibitors in the treatment of neoplastic fever.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:4

    Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship

2003
Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, May-15, Volume: 12, Issue:10

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2006

Other Studies

10 other studies available for rofecoxib and Neoplasms

ArticleYear
One-Step Transformation from Rofecoxib to a COX-2 NIR Probe for Human Cancer Tissue/Organoid Targeted Bioimaging.
    ACS applied bio materials, 2021, 03-15, Volume: 4, Issue:3

    Topics: Animals; Biocompatible Materials; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fluorescent Dyes; H

2021
Automatic evaluation of cyclooxygenase 2 inhibition induced by metal-based anticancer compounds.
    Journal of inorganic biochemistry, 2021, Volume: 218

    Topics: Antineoplastic Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Lactones; Metals; Neop

2021
Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-15, Volume: 10, Issue:10

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis;

2004
Vioxx withdrawal alarms cancer prevention researchers.
    Journal of the National Cancer Institute, 2004, Dec-01, Volume: 96, Issue:23

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arthritis; Celecoxib; Cyc

2004
Clinical trials. Nail-biting time for trials of COX-2 drugs.
    Science (New York, N.Y.), 2004, Dec-03, Volume: 306, Issue:5702

    Topics: Alzheimer Disease; Anticarcinogenic Agents; Cardiovascular Diseases; Celecoxib; Controlled Clinical

2004
Don't throw out the baby with the bathwater!
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:2

    Topics: Advertising; Cardiovascular Diseases; Child; Child Welfare; Clinical Trials as Topic; Cyclooxygenase

2005
COX-2 inhibitors: cancer prevention or cardiovascular risk?
    The Lancet. Oncology, 2005, Volume: 6, Issue:2

    Topics: Adenoma; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy

2005
Researchers plan to continue to study COX-2 inhibitors in cancer treatment and prevention.
    Journal of the National Cancer Institute, 2005, Apr-20, Volume: 97, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Ce

2005
Early trials probe COX-2 inhibitors' cancer-fighting potential.
    Journal of the National Cancer Institute, 1999, Jul-21, Volume: 91, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials as Topic; Colonic Neoplasms; Cyc

1999
Targeting angiogenic processes by combination rofecoxib and ionizing radiation.
    American journal of clinical oncology, 2001, Volume: 24, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Aorta; Apoptosis; Cell Division; Cells, Cultured; Cyclooxygenase 2

2001