rofecoxib has been researched along with Mitochondrial Diseases in 1 studies
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid is an endogenous excitotoxin that causes neurotoxicity in diverse areas of the brain and produces motor dysfunction." | 1.36 | Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats. ( Kalonia, H; Kumar, A; Kumar, P; Nehru, B, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalonia, H | 1 |
| Kumar, P | 1 |
| Kumar, A | 1 |
| Nehru, B | 1 |
1 other study available for rofecoxib and Mitochondrial Diseases
| Article | Year |
|---|---|
Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats.
Topics: Animals; Ataxia; Body Weight; Cell Survival; Corpus Striatum; Cyclooxygenase 2 Inhibitors; Lactones; | 2010 |