rofecoxib has been researched along with Migraine Disorders in 10 studies
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibuprofen was included as a reference nonselective NSAID." | 2.72 | Rofecoxib in the acute treatment of migraine: a randomized controlled clinical trial. ( Barraclough, E; Dahlof, C; Klipfel, M; Lines, C; Loeys, T; Malbecq, W; Reines, S; Saper, J; So, Y; Tfelt-Hansen, P; Visser, H; Yuen, E, 2006) |
| "Fourteen patients completed baseline and rofecoxib dosing for 2 menstrual cycles." | 2.71 | Rofecoxib in the prevention of perimenstrual migraine: an open-label pilot trial. ( Adelman, JU; Mannix, LK; Von Seggern, RL, 2004) |
| "Rofecoxib 25 and 50 mg were superior to placebo in providing pain freedom at 2 hours, 24-hour sustained headache relief, and 24-hour sustained pain freedom; in reducing photophobia, phonophobia, nausea (50 mg only), and functional disability at 2 hours after dose; and in improving some quality-of-life scores over 24 hours." | 2.71 | Randomized, placebo-controlled trial of rofecoxib in the acute treatment of migraine. ( Brandes, J; Diamond, M; Goldstein, J; Lines, C; Malbecq, W; Reines, S; Silberstein, S; Tepper, S; Venkatraman, S; Visser, WH; Vrijens, F; Winner, P; Yuen, E, 2004) |
| "Rizatriptan is an effective and fast acting drug for the acute treatment of migraine." | 2.71 | Rizatriptan versus rizatriptan plus rofecoxib versus rizatriptan plus tolfenamic acid in the acute treatment of migraine. ( Bigal, ME; Krymchantowski, AV, 2004) |
| "Both ibuprofen and rofecoxib were superior to placebo in aborting an acute migraine attack, and there was no significant difference in their efficacy in an acute migraine attack." | 2.71 | Rofecoxib versus ibuprofen for acute treatment of migraine: a randomised placebo controlled trial. ( Jose, M; Kalita, J; Misra, UK, 2004) |
| "Rizatriptan is an effective and fast acting drug for the acute treatment of migraine." | 2.70 | Rizatriptan combined with rofecoxib vs. rizatriptan for the acute treatment of migraine: an open label pilot study. ( Barbosa, JS; Krymchantowski, AV, 2002) |
| "The disability of migraine attacks results in considerable economic and social losses." | 2.43 | Rofecoxib in migraine. ( Bigal, ME; Krymchantowski, AV, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peres, MF | 2 |
| Silberstein, SD | 1 |
| Von Seggern, RL | 1 |
| Mannix, LK | 1 |
| Adelman, JU | 1 |
| Silberstein, S | 1 |
| Tepper, S | 1 |
| Brandes, J | 1 |
| Diamond, M | 1 |
| Goldstein, J | 1 |
| Winner, P | 1 |
| Venkatraman, S | 1 |
| Vrijens, F | 1 |
| Malbecq, W | 2 |
| Lines, C | 2 |
| Visser, WH | 1 |
| Reines, S | 2 |
| Yuen, E | 2 |
| Krymchantowski, AV | 3 |
| Bigal, ME | 2 |
| Misra, UK | 1 |
| Jose, M | 1 |
| Kalita, J | 1 |
| Saper, J | 1 |
| Dahlof, C | 1 |
| So, Y | 1 |
| Tfelt-Hansen, P | 1 |
| Loeys, T | 1 |
| Barraclough, E | 1 |
| Klipfel, M | 1 |
| Visser, H | 1 |
| Zukerman, E | 1 |
| Barbosa, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| : An End to the Yom Kippur (and Ramadan) Headache: A Double Blind Placebo Controlled Trial of Prophylactic Rofecoxib in Preventing Ritual Fasting Headache.[NCT00263094] | 220 participants | Interventional | 2004-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for rofecoxib and Migraine Disorders
| Article | Year |
|---|---|
Rofecoxib in migraine.
Topics: Cyclooxygenase 2 Inhibitors; Expert Testimony; Humans; Lactones; Migraine Disorders; Sulfones | 2005 |
6 trials available for rofecoxib and Migraine Disorders
| Article | Year |
|---|---|
Rofecoxib in the prevention of perimenstrual migraine: an open-label pilot trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Administration Schedule; Fe | 2004 |
Randomized, placebo-controlled trial of rofecoxib in the acute treatment of migraine.
Topics: Acute Disease; Adult; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Meth | 2004 |
Rizatriptan versus rizatriptan plus rofecoxib versus rizatriptan plus tolfenamic acid in the acute treatment of migraine.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhi | 2004 |
Rofecoxib versus ibuprofen for acute treatment of migraine: a randomised placebo controlled trial.
Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2004 |
Rofecoxib in the acute treatment of migraine: a randomized controlled clinical trial.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dizziness; Dose-Response Relationship | 2006 |
Rizatriptan combined with rofecoxib vs. rizatriptan for the acute treatment of migraine: an open label pilot study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Therapy, | 2002 |
3 other studies available for rofecoxib and Migraine Disorders
| Article | Year |
|---|---|
Hemicrania continua responds to cyclooxygenase-2 inhibitors.
Topics: Celecoxib; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Lactones; Male; Migraine Disorde | 2002 |
[Selective COX 2 inhibitor rofecoxib. To "defy" the pain].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors | 2003 |
Hemicrania continua responsive to rofecoxib.
Topics: Enzyme Inhibitors; Female; Humans; Lactones; Middle Aged; Migraine Disorders; Sulfones | 2000 |