Page last updated: 2024-11-04

rofecoxib and Lung Neoplasms

rofecoxib has been researched along with Lung Neoplasms in 9 studies

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Gefitinib 250 mg/d was combined with rofecoxib (dose escalated from 12."2.73Combination therapy with gefitinib and rofecoxib in patients with platinum-pretreated relapsed non small-cell lung cancer. ( Botwood, N; Carbone, D; Danson, S; Dunlop, D; O'Byrne, KJ; Ranson, M; Taguchi, F, 2007)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patel, S1
Vetale, S1
Teli, P1
Mistry, R1
Chiplunkar, S1
Peluffo, GD1
Stillitani, I1
Rodríguez, VA1
Diament, MJ1
Klein, SM1
Tanaka, T1
Delong, PA1
Amin, K1
Henry, A1
Kruklitis, R1
Kapoor, V1
Kaiser, LR1
Albelda, SM1
Spano, JP1
Chouahnia, K1
Morère, JF1
Kozak, KR1
Milne, GL1
Morrow, JD1
Cuiffo, BP1
Gridelli, C1
Gallo, C1
Ceribelli, A1
Gebbia, V1
Gamucci, T1
Ciardiello, F1
Carozza, F1
Favaretto, A1
Daniele, B1
Galetta, D1
Barbera, S1
Rosetti, F1
Rossi, A1
Maione, P1
Cognetti, F1
Testa, A1
Di Maio, M1
Morabito, A1
Perrone, F1
Harris, RE1
Beebe-Donk, J1
Alshafie, GA1
Alam, M1
Wang, JH1
Coffey, JC1
Qadri, SS1
O'Donnell, A1
Aherne, T1
Redmond, HP1
O'Byrne, KJ1
Danson, S1
Dunlop, D1
Botwood, N1
Taguchi, F1
Carbone, D1
Ranson, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II-III, Factorial Multicenter Randomized Trial Evaluating the Addition of Rofecoxib to Polycht With Cispatin and Gemcitabine and Fixed Dose Rate Infusion of Gem in Association With Cisplatin in 1st-line for Advanced NSCLC[NCT00385606]Phase 2/Phase 3400 participants (Actual)Interventional2003-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for rofecoxib and Lung Neoplasms

ArticleYear
[Cyclooxygenase 2 inhibitors and lung carcinoma].
    Bulletin du cancer, 2004, Volume: 91 Suppl 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cele

2004

Trials

2 trials available for rofecoxib and Lung Neoplasms

ArticleYear
Factorial phase III randomised trial of rofecoxib and prolonged constant infusion of gemcitabine in advanced non-small-cell lung cancer: the GEmcitabine-COxib in NSCLC (GECO) study.
    The Lancet. Oncology, 2007, Volume: 8, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell;

2007
Combination therapy with gefitinib and rofecoxib in patients with platinum-pretreated relapsed non small-cell lung cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-01, Volume: 25, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small

2007

Other Studies

6 other studies available for rofecoxib and Lung Neoplasms

ArticleYear
IL-10 production in non-small cell lung carcinoma patients is regulated by ERK, P38 and COX-2.
    Journal of cellular and molecular medicine, 2012, Volume: 16, Issue:3

    Topics: Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cyclooxygenase 2; Cycloo

2012
Reduction of tumor progression and paraneoplastic syndrome development in murine lung adenocarcinoma by nonsteroidal antiinflammatory drugs.
    International journal of cancer, 2004, Jul-20, Volume: 110, Issue:6

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Survival; Chem

2004
Treatment of lung cancer using clinically relevant oral doses of the cyclooxygenase-2 inhibitor rofecoxib: potential value as adjuvant therapy after surgery.
    Annals of surgery, 2005, Volume: 241, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tum

2005
Hypertrophic osteoarthropathy pathogenesis: a case highlighting the potential role for cyclo-oxygenase-2-derived prostaglandin E2.
    Nature clinical practice. Rheumatology, 2006, Volume: 2, Issue:8

    Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; F

2006
Reduced risk of human lung cancer by selective cyclooxygenase 2 (COX-2) blockade: results of a case control study.
    International journal of biological sciences, 2007, Jun-13, Volume: 3, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Celecoxib; Chem

2007
Characterization of the effects of cyclooxygenase-2 inhibition in the regulation of apoptosis in human small and non-small cell lung cancer cell lines.
    Annals of surgical oncology, 2007, Volume: 14, Issue:9

    Topics: Analysis of Variance; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small

2007