Page last updated: 2024-11-04

rofecoxib and Liver Neoplasms

rofecoxib has been researched along with Liver Neoplasms in 9 studies

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"To determine whether the nonselective and relatively inexpensive nonsteroidal anti-inflammatory drug ibuprofen would be effective in inhibiting colorectal cancer and might improve mortality in a mouse model."7.73Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer. ( Albert, A; Chang, AJ; Liu, TC; Sangha, S; Wolfe, MM; Yao, M; Zhou, W, 2005)
"To know whether octreotide combined with rofecoxib would enhance the inhibitory effect on proliferation of hepatocellular carcinoma (HCC) in vitro and in vivo."7.72[The combination of octreotide to rofecoxib enhanced the inhibitory effect on growth of human hepatocellular carcinoma]. ( Liu, CL; Tang, CW; Zhou, XC, 2003)
"Rofecoxib-treated metastases had a 29% decrease in MVD (mean, 25."6.71The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases. ( Fenwick, SW; Hull, MA; Lodge, JP; Toogood, GJ, 2003)
"To determine whether the nonselective and relatively inexpensive nonsteroidal anti-inflammatory drug ibuprofen would be effective in inhibiting colorectal cancer and might improve mortality in a mouse model."3.73Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer. ( Albert, A; Chang, AJ; Liu, TC; Sangha, S; Wolfe, MM; Yao, M; Zhou, W, 2005)
"To know whether octreotide combined with rofecoxib would enhance the inhibitory effect on proliferation of hepatocellular carcinoma (HCC) in vitro and in vivo."3.72[The combination of octreotide to rofecoxib enhanced the inhibitory effect on growth of human hepatocellular carcinoma]. ( Liu, CL; Tang, CW; Zhou, XC, 2003)
"Systemic therapy for advanced hepatocellular carcinoma (HCC) is still challenging."2.84Communicative reprogramming non-curative hepatocellular carcinoma with low-dose metronomic chemotherapy, COX-2 inhibitor and PPAR-gamma agonist: a phase II trial. ( Andreesen, R; Endlicher, E; Ghibelli, L; Hackl, C; Herr, W; Klebl, F; Reichle, A; Schulz, U; Vogelhuber, M; Walter, I; Wiedmann, K; Wiest, R, 2017)
" Patients were prospectively randomised to receive open-label octreotide 30 mg monthly alone (n = 39) or in combination with rofecoxib (up to 50 mg bid daily, n = 32) for a minimum of six months, or until death occurred."2.73Octreotide alone or in combination with rofecoxib as palliative treatment for advanced hepatocellular cancer. ( Malfertheiner, P; Röcken, C; Treiber, G; Wex, T, 2007)
"Rofecoxib-treated metastases had a 29% decrease in MVD (mean, 25."2.71The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases. ( Fenwick, SW; Hull, MA; Lodge, JP; Toogood, GJ, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Walter, I1
Schulz, U1
Vogelhuber, M1
Wiedmann, K1
Endlicher, E1
Klebl, F1
Andreesen, R1
Herr, W1
Ghibelli, L1
Hackl, C1
Wiest, R1
Reichle, A2
Plikat, K1
Elmlinger, MW1
Schölmerich, J1
Liu, CL1
Tang, CW1
Zhou, XC1
Fenwick, SW1
Toogood, GJ2
Lodge, JP1
Hull, MA2
Yao, M1
Zhou, W1
Sangha, S1
Albert, A1
Chang, AJ1
Liu, TC1
Wolfe, MM1
Chalmers, CR1
Wilson, DJ1
Ward, J1
Robinson, PJ1
Treiber, G2
Wex, T2
Röcken, C2
Fostitsch, P1
Malfertheiner, P2
Song, HJ1
Kim, YS2
Han, CH1
Jang, JY1
Kim, JH1
Cheon, YK1
Moon, JH1
Cho, YD1
Shim, CS1
Kwon, KH1
Kim, BS1

Trials

4 trials available for rofecoxib and Liver Neoplasms

ArticleYear
Communicative reprogramming non-curative hepatocellular carcinoma with low-dose metronomic chemotherapy, COX-2 inhibitor and PPAR-gamma agonist: a phase II trial.
    Medical oncology (Northwood, London, England), 2017, Nov-02, Volume: 34, Issue:12

    Topics: Administration, Metronomic; Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols

2017
The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases.
    Gastroenterology, 2003, Volume: 125, Issue:3

    Topics: Aged; Apoptosis; Cell Division; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

2003
Impact of biomarkers on disease survival and progression in patients treated with octreotide for advanced hepatocellular carcinoma.
    Journal of cancer research and clinical oncology, 2006, Volume: 132, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Hepatocellular;

2006
Octreotide alone or in combination with rofecoxib as palliative treatment for advanced hepatocellular cancer.
    Zeitschrift fur Gastroenterologie, 2007, Volume: 45, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellul

2007

Other Studies

5 other studies available for rofecoxib and Liver Neoplasms

ArticleYear
[Hypoglycemia associated with the production of insulin-like growth factor (IGF)-II by a hemangiopericytoma].
    Deutsche medizinische Wochenschrift (1946), 2003, Feb-07, Volume: 128, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alky

2003
[The combination of octreotide to rofecoxib enhanced the inhibitory effect on growth of human hepatocellular carcinoma].
    Zhonghua nei ke za zhi, 2003, Volume: 42, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cell Pro

2003
Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Feb-15, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Cell Line,

2005
Antiangiogenic activity of the selective cyclooxygenase 2 inhibitor rofecoxib in human colorectal cancer liver metastases.
    Gut, 2006, Volume: 55, Issue:7

    Topics: Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Endostatins; Humans; Lactones; Liver Neoplasms; N

2006
[A case of complete regression of hepatocellular carcinoma during administration of COX-2 inhibitor].
    The Korean journal of hepatology, 2006, Volume: 12, Issue:3

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Celeco

2006