rofecoxib has been researched along with Labor, Premature in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rofecoxib has a significant but reversible effect on fetal renal function and the ductus arteriosus." | 2.71 | TOCOX--a randomised, double-blind, placebo-controlled trial of rofecoxib (a COX-2-specific prostaglandin inhibitor) for the prevention of preterm delivery in women at high risk. ( Bennett, PR; Groom, KM; Jones, BA; Seed, P; Shennan, AH, 2005) |
| "Rofecoxib use was associated with an increased risk for preterm birth and preterm premature rupture of membranes (PPROM)." | 2.48 | Cyclo-oxygenase (COX) inhibitors for preventing preterm labour. ( Khanprakob, T; Laopaiboon, M; Lumbiganon, P; Sangkomkamhang, US, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khanprakob, T | 1 |
| Laopaiboon, M | 1 |
| Lumbiganon, P | 1 |
| Sangkomkamhang, US | 1 |
| McWhorter, J | 1 |
| Carlan, SJ | 1 |
| OLeary, TD | 1 |
| Richichi, K | 1 |
| OBrien, WF | 1 |
| Groom, KM | 1 |
| Shennan, AH | 1 |
| Jones, BA | 1 |
| Seed, P | 1 |
| Bennett, PR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Trial of a COX-2 Inhibitor for the Treatment of Women With Preeclampsia[NCT00442676] | Phase 2 | 0 participants (Actual) | Interventional | 2009-06-30 | Withdrawn (stopped due to No patients were recruited. Treatment drug expired.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for rofecoxib and Labor, Premature
| Article | Year |
|---|---|
Cyclo-oxygenase (COX) inhibitors for preventing preterm labour.
Topics: Adult; Cyclooxygenase 2 Inhibitors; Female; Humans; Lactones; Obstetric Labor, Premature; Pregnancy; | 2012 |
2 trials available for rofecoxib and Labor, Premature
| Article | Year |
|---|---|
Rofecoxib versus magnesium sulfate to arrest preterm labor: a randomized trial.
Topics: Administration, Oral; Adult; Cyclooxygenase Inhibitors; Female; Humans; Lactones; Magnesium Sulfate; | 2004 |
TOCOX--a randomised, double-blind, placebo-controlled trial of rofecoxib (a COX-2-specific prostaglandin inhibitor) for the prevention of preterm delivery in women at high risk.
Topics: Adult; Blood Flow Velocity; Cyclooxygenase Inhibitors; Double-Blind Method; Ductus Arteriosus; Femal | 2005 |