Page last updated: 2024-11-04

rofecoxib and Ischemia

rofecoxib has been researched along with Ischemia in 4 studies

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"We assessed the effect of rofecoxib, a cyclo-oxygenase-2 inhibitor, and tramadol, a centrally acting analgesic, on both delayed-onset muscle soreness (DOMS) and experimentally induced ischaemic pain."9.11Rofecoxib and tramadol do not attenuate delayed-onset muscle soreness or ischaemic pain in human volunteers. ( Fuller, A; Loram, LC; Mitchell, D, 2005)
"We assessed the effect of rofecoxib, a cyclo-oxygenase-2 inhibitor, and tramadol, a centrally acting analgesic, on both delayed-onset muscle soreness (DOMS) and experimentally induced ischaemic pain."5.11Rofecoxib and tramadol do not attenuate delayed-onset muscle soreness or ischaemic pain in human volunteers. ( Fuller, A; Loram, LC; Mitchell, D, 2005)
"Indomethacin treatment induced a better renal function (serum urea) when compared to control animals at 24, 48 and 72 h (219+/-54."1.33Cyclooxygenase 1 and/or 2 blockade ameliorates the renal tissue damage triggered by ischemia and reperfusion injury. ( Câmara, NO; Cenedeze, MA; Feitoza, CQ; Gonçalves, GM; Pacheco-Silva, A; Pinheiro, HS; Santos, OF, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakagiri, A1
Murakami, M1
Feitoza, CQ1
Câmara, NO1
Pinheiro, HS1
Gonçalves, GM1
Cenedeze, MA1
Pacheco-Silva, A1
Santos, OF1
Loram, LC1
Mitchell, D1
Fuller, A1
Rashid, A1
Dale, G1
Hennebry, T1

Trials

1 trial available for rofecoxib and Ischemia

ArticleYear
Rofecoxib and tramadol do not attenuate delayed-onset muscle soreness or ischaemic pain in human volunteers.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:12

    Topics: Adult; Creatine Kinase; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Exerci

2005

Other Studies

3 other studies available for rofecoxib and Ischemia

ArticleYear
Roles of NADPH oxidase in occurrence of gastric damage and expression of cyclooxygenase-2 during ischemia/reperfusion in rat stomachs.
    Journal of pharmacological sciences, 2009, Volume: 111, Issue:4

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Gastric M

2009
Cyclooxygenase 1 and/or 2 blockade ameliorates the renal tissue damage triggered by ischemia and reperfusion injury.
    International immunopharmacology, 2005, Volume: 5, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2005
Cold leg in patient with high coated platelets: possible association with the use of rofecoxib.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:6

    Topics: Acute Disease; Blood Platelets; Coronary Artery Disease; Cyclooxygenase 2 Inhibitors; Eptifibatide;

2006