Page last updated: 2024-11-04

rofecoxib and Intestinal Perforation

rofecoxib has been researched along with Intestinal Perforation in 4 studies

Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.

Research Excerpts

ExcerptRelevanceReference
"To update the results of a previously performed analysis of the incidence of upper GI perforations, symptomatic gastroduodenal ulcers, and upper GI bleeding (PUBs) with rofecoxib compared with non-selective NSAIDs."4.82The upper gastrointestinal safety of rofecoxib vs. NSAIDs: an updated combined analysis. ( Bolognese, JA; Reicin, AS; Simon, TJ; Watson, DJ; Yu, Q, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watson, DJ1
Yu, Q1
Bolognese, JA1
Reicin, AS1
Simon, TJ2
Villalba, L1
Witter, J1
Calvo, N1
Iversen, E1
Munck, LK1
Hawkey, CJ1
Jackson, L1
Harper, SE1
Mortensen, E1
Lines, CR1

Reviews

2 reviews available for rofecoxib and Intestinal Perforation

ArticleYear
The upper gastrointestinal safety of rofecoxib vs. NSAIDs: an updated combined analysis.
    Current medical research and opinion, 2004, Volume: 20, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind Method; Duodenal Ul

2004
Review article: the gastrointestinal safety profile of rofecoxib, a highly selective inhibitor of cyclooxygenase-2, in humans.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygena

2001

Other Studies

2 other studies available for rofecoxib and Intestinal Perforation

ArticleYear
Rofecoxib, Merck, and the FDA.
    The New England journal of medicine, 2004, Dec-30, Volume: 351, Issue:27

    Topics: Cardiovascular Diseases; Cyclooxygenase Inhibitors; Drug Approval; Drug Industry; Drug Labeling; His

2004
[Intestinal side effects of COX-2 inhibitors].
    Ugeskrift for laeger, 2006, Mar-27, Volume: 168, Issue:13

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colonic Diseases; Colonic Pouches;

2006