rofecoxib has been researched along with Hemorrhage in 6 studies
Hemorrhage: Bleeding or escape of blood from a vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness and adverse effects of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) for the primary or secondary prevention of dementia." | 9.05 | Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia. ( Devane, D; Jordan, F; Kelly, JP; McGuinness, B; Murphy, K; Passmore, P; Quinn, TJ; Tudur Smith, C, 2020) |
| "Angioedema is a recognised side effect of rofecoxib, a cyclo-oxygenase-2 (COX-2) inhibitor." | 7.71 | Fatal haemorrhagic pulmonary oedema and associated angioedema after the ingestion of rofecoxib. ( Kumar, NP; Ramasamy, KA; Snape, J; Wild, G, 2002) |
| "Rofecoxib is a selective COX-2 inhibitor that does not interfere with platelet function and is associated with fewer bleeding complications than other nonsteroidal anti-inflammatory agents (NSAIDs)." | 5.11 | Rofecoxib administration to paediatric patients undergoing adenotonsillectomy. ( Chiavacci, R; Fazi, LM; McCormick, L; Rose, JB; Sheeran, PW, 2004) |
| "To evaluate the effectiveness and adverse effects of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) for the primary or secondary prevention of dementia." | 5.05 | Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia. ( Devane, D; Jordan, F; Kelly, JP; McGuinness, B; Murphy, K; Passmore, P; Quinn, TJ; Tudur Smith, C, 2020) |
| " Thus, physiological and pathophysiological roles of COX-2 were considered from the standpoint of clinical effects of the two latest COX-2 selective inhibitors, celecoxib and rofecoxib, on inflammation, pain, fever and colorectal cancer together with their adverse effects on gastrointestinal, renal and platelet functions; and the usefulness and limits of COX-2-selective inhibitors were discussed with the trends of new NSAIDs development." | 4.81 | [Cyclooxygenase (COX)-2 selective inhibitors: aspirin, a dual COX-1/COX-2 inhibitor, to COX-2 selective inhibitors]. ( Nakamura, H, 2001) |
| "It can be postulated that in addition to the risk of heart attack and stroke, rofecoxib users were at increased risk of hemorrhage, in addition to other thrombotic and embolic adverse events, which was exacerbated in those taking blood thinners or NSAIDs." | 3.75 | Postmarketing surveillance of serious adverse events associated with the use of rofecoxib from 1999-2002. ( Barry, WT; Bottone, FG, 2009) |
| "Angioedema is a recognised side effect of rofecoxib, a cyclo-oxygenase-2 (COX-2) inhibitor." | 3.71 | Fatal haemorrhagic pulmonary oedema and associated angioedema after the ingestion of rofecoxib. ( Kumar, NP; Ramasamy, KA; Snape, J; Wild, G, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jordan, F | 1 |
| Quinn, TJ | 1 |
| McGuinness, B | 1 |
| Passmore, P | 1 |
| Kelly, JP | 1 |
| Tudur Smith, C | 1 |
| Murphy, K | 1 |
| Devane, D | 1 |
| Bottone, FG | 1 |
| Barry, WT | 1 |
| Kumar, NP | 1 |
| Wild, G | 1 |
| Ramasamy, KA | 1 |
| Snape, J | 1 |
| Joshi, W | 1 |
| Connelly, NR | 1 |
| Reuben, SS | 1 |
| Wolckenhaar, M | 1 |
| Thakkar, N | 1 |
| Sheeran, PW | 1 |
| Rose, JB | 1 |
| Fazi, LM | 1 |
| Chiavacci, R | 1 |
| McCormick, L | 1 |
| Nakamura, H | 1 |
2 reviews available for rofecoxib and Hemorrhage
| Article | Year |
|---|---|
Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Age | 2020 |
[Cyclooxygenase (COX)-2 selective inhibitors: aspirin, a dual COX-1/COX-2 inhibitor, to COX-2 selective inhibitors].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Clinical Trials as Topic; Colo | 2001 |
2 trials available for rofecoxib and Hemorrhage
| Article | Year |
|---|---|
An evaluation of the safety and efficacy of administering rofecoxib for postoperative pain management.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2003 |
Rofecoxib administration to paediatric patients undergoing adenotonsillectomy.
Topics: Adenoidectomy; Child; Child, Preschool; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Adminis | 2004 |
2 other studies available for rofecoxib and Hemorrhage
| Article | Year |
|---|---|
Postmarketing surveillance of serious adverse events associated with the use of rofecoxib from 1999-2002.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Drug Interactions; Dr | 2009 |
Fatal haemorrhagic pulmonary oedema and associated angioedema after the ingestion of rofecoxib.
Topics: Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Fatal Outcome; Hemor | 2002 |