Page last updated: 2024-08-16

rofecoxib and Hematochezia

rofecoxib has been researched along with Hematochezia in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.71)	18.2507
2000's	31 (88.57)	29.6817
2010's	2 (5.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dejaco, C; Jaksch, W; Schirmer, M	1
Gøtzsche, PC; Jørgensen, AW; Jørgensen, KJ	1
Gunnell, D; Martin, RM; Metcalfe, C; Wheeler, BW	1
Anderson, GM; Austin, PC; Juurlink, DN; Kopp, A; Laupacis, A; Mamdani, M; Naglie, G; Rochon, PA	1
Gornet, JM; Hassani, Z; Lémann, M; Modiglian, R	1
Layton, D; Riley, J; Shakir, SA; Wilton, LV	1
Hawkey, CJ; James, MW	1
Burke, TA; Goldstein, JL; MacDonald, TM; Morant, SV; Pettitt, D	1
Oviedo, JA; Wolfe, MM	1
Hayashi, Y; Kubo, Y; Takeuchi, K; Tanaka, A	1
Lamarque, D	1
Bolognese, JA; Reicin, AS; Simon, TJ; Watson, DJ; Yu, Q	1
Bannwarth, B; Logeart, I; Vergult, G	1
Furberg, CD; Psaty, BM	1
Drazen, JM	1
Boivin, JF; Ducruet, T; Moore, N; Moride, Y; Perreault, S; Zhao, S	1
Feltri, M; Meucci, G; Minoli, G; Radaelli, F; Spinzi, G; Terruzzi, V	1
McCarthy, DM	1
Nedjar, H; Rahme, E	1
Bolognese, JA; Harper, SE; Jensen, DM; Langman, MJ; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL	1
Bolognese, JA; Bowen, B; Cagliola, A; Hunt, RH; James, C; Mortensen, ER; Quan, H; Simon, TJ	1
Davis, JV; Linder, JD; Mönkemüller, KE; Wilcox, CM	1
Bombardier, C; Burgos-Vargas, R; Davis, B; Day, R; Ferraz, MB; Hawkey, CJ; Hochberg, MC; Kvien, TK; Laine, L; Reicin, A; Schnitzer, TJ; Shapiro, D	1
Delgado Fernández, M; Diez García, F; Zambrana García, JL	1
Caroli, A; Monica, F	1
García Rodríguez, LA; Patrignani, P; Patrono, C	1
Wardle, EN	1
Attard, CL; Kong, SX; Marentette, MA; Marshall, JK; Pellissier, JM	1
Bonnel, RA; Brinker, AD; Feight, AG; Nourjah, P	1
de La Serna Higuera, C; Martín Arribas, MI; Martínez Moreno, J; Rodríguez-Gómez, SJ	1
Foral, PA; Nystrom, KK; Wilson, AF	1
Borralho, P; Farricha, V; Freitas, J; Nascimento, I; Paramés, A	1
Araki, H; Hase, S; Komoike, Y; Takeuchi, K; Tanaka, A	1

Reviews

7 review(s) available for rofecoxib and Hematochezia

Article	Year
4 years after withdrawal of rofecoxib: where do we stand today? Rheumatology international, 2008, Volume: 28, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Contraindications; Cyclooxygenase 2 Inhibitors; Drug and Narcotic Control; Drug Approval; Drug Therapy, Combination; Europe; Gastrointestinal Hemorrhage; Humans; Lactones; Proton Pump Inhibitors; Rheumatic Diseases; Risk; Sulfones; United States	2008
Assessment of non-steroidal anti-inflammatory drug (NSAID) damage in the human gastrointestinal tract. British journal of clinical pharmacology, 2003, Volume: 56, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endoscopy, Gastrointestinal; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Isoenzymes; Lactones; Membrane Proteins; Prognosis; Prostaglandin-Endoperoxide Synthases; Radionuclide Imaging; Randomized Controlled Trials as Topic; Recurrence; Sulfones	2003
Gastroprotection by coxibs: what do the Celecoxib Long-Term Arthritis Safety Study and the Vioxx Gastrointestinal Outcomes Research Trial tell us? Rheumatic diseases clinics of North America, 2003, Volume: 29, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Inhibitors; Gastrointestinal Hemorrhage; Humans; Lactones; Misoprostol; Omeprazole; Osteoarthritis; Proton Pump Inhibitors; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulfones	2003
The upper gastrointestinal safety of rofecoxib vs. NSAIDs: an updated combined analysis. Current medical research and opinion, 2004, Volume: 20, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind Method; Duodenal Ulcer; Gastrointestinal Hemorrhage; Humans; Incidence; Intestinal Perforation; Lactones; Randomized Controlled Trials as Topic; Risk Factors; Stomach Ulcer; Sulfones	2004
Ulcers, Helicobacter pylori infection, platelets and gastrointestinal complications of non-steroidal anti-inflammatory drugs: what are the connections? The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 2002, Issue:587 Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Hemorrhage; Helicobacter Infections; Humans; Ibuprofen; Lactones; Naproxen; Peptic Ulcer; Risk Factors; Sulfones	2002
Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs. JAMA, 1999, Nov-24, Volume: 282, Issue:20 Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Nabumetone; Osteoarthritis; Peptic Ulcer; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulfones	1999
Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs. The Journal of clinical investigation, 2001, Volume: 108, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Blood Platelets; Cardiovascular Diseases; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Depression, Chemical; Dinoprostone; Epoprostenol; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Incidence; Intestinal Mucosa; Isoenzymes; Lactones; Membrane Proteins; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Randomized Controlled Trials as Topic; Substrate Specificity; Sulfonamides; Sulfones; Thromboembolism; Thromboxane A2; Treatment Outcome	2001

Trials

2 trial(s) available for rofecoxib and Hematochezia

Article	Year
A randomized trial measuring fecal blood loss after treatment with rofecoxib, ibuprofen, or placebo in healthy subjects. The American journal of medicine, 2000, Aug-15, Volume: 109, Issue:3 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromium Radioisotopes; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Erythrocytes; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Occult Blood; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Radionuclide Imaging; Radiopharmaceuticals; Reference Values; Sulfones; Treatment Outcome	2000
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. The New England journal of medicine, 2000, 11-23, Volume: 343, Issue:21 Topics: Adult; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Duodenal Obstruction; Female; Gastric Outlet Obstruction; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Naproxen; Peptic Ulcer; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Sulfones	2000

Article

Year

A randomized trial measuring fecal blood loss after treatment with rofecoxib, ibuprofen, or placebo in healthy subjects.

The American journal of medicine, 2000, Aug-15, Volume: 109, Issue:3

Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromium Radioisotopes; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Erythrocytes; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Occult Blood; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Radionuclide Imaging; Radiopharmaceuticals; Reference Values; Sulfones; Treatment Outcome

2000

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.

The New England journal of medicine, 2000, 11-23, Volume: 343, Issue:21

Topics: Adult; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Duodenal Obstruction; Female; Gastric Outlet Obstruction; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Naproxen; Peptic Ulcer; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Sulfones

2000

Other Studies

26 other study(ies) available for rofecoxib and Hematochezia

Article	Year
Unbalanced reporting of benefits and harms in abstracts on rofecoxib. European journal of clinical pharmacology, 2010, Volume: 66, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Lactones; Sulfones; Thrombosis	2010
International regulatory activity restricting COX-2 inhibitor use and deaths due to gastrointestinal haemorrhage and myocardial infarction. Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:8 Topics: Acute Disease; Aged; Aged, 80 and over; Cyclooxygenase 2 Inhibitors; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Internationality; Lactones; Male; Middle Aged; Myocardial Infarction; Safety-Based Drug Withdrawals; Sulfones; Thrombolytic Therapy	2010
Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs. BMJ (Clinical research ed.), 2002, Sep-21, Volume: 325, Issue:7365 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cohort Studies; Cyclooxygenase 2; Diclofenac; Drug Combinations; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hospitalization; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Misoprostol; Multivariate Analysis; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Risk Factors; Sulfonamides; Sulfones	2002
Exacerbation of Crohn's colitis with severe colonic hemorrhage in a patient on rofecoxib. The American journal of gastroenterology, 2002, Volume: 97, Issue:12 Topics: Adult; Colonic Diseases; Crohn Disease; Cyclooxygenase Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; Lactones; Sulfones	2002
Safety profile of rofecoxib as used in general practice in England: results of a prescription-event monitoring study. British journal of clinical pharmacology, 2003, Volume: 55, Issue:2 Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Prescriptions; Dyspepsia; England; Family Practice; Female; Gastrointestinal Hemorrhage; Humans; Lactones; Male; Middle Aged; Sulfones; Surveys and Questionnaires	2003
[Gastrointestinal complications caused by NSAIDs. Over 60% of arthrosis patients are endangered]. MMW Fortschritte der Medizin, 2003, Mar-06, Volume: 145, Issue:10 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhage; Humans; Lactones; Pyrazoles; Risk Factors; Sulfonamides; Sulfones; Time Factors	2003
Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs. Gut, 2003, Volume: 52, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bias; Celecoxib; Cohort Studies; Databases, Factual; Family Practice; Female; Gastrointestinal Hemorrhage; Humans; Lactones; Male; Meloxicam; Middle Aged; Pyrazoles; Risk Factors; Sulfonamides; Sulfones; Thiazines; Thiazoles	2003
Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility. Digestive diseases and sciences, 2004, Volume: 49, Issue:2 Topics: Animals; Atropine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastrointestinal Motility; Indomethacin; Isoenzymes; Lactones; Male; Omeprazole; Peroxidase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stomach; Stomach Ulcer; Sulfones	2004
[Safety of selective inhibitors of inducible cyclooxygenase-2 taken for a long period]. Bulletin du cancer, 2004, Volume: 91 Spec No Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Hypertension; Isoenzymes; Kidney; Lactones; Membrane Proteins; Myocardial Infarction; Neoplasm Proteins; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Risk Factors; Sulfonamides; Sulfones	2004
[Prescribing patterns of rofecoxib in the primary care setting: results of a French survey]. La Revue de medecine interne, 2004, Volume: 25, Issue:10 Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Chi-Square Distribution; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Drug Prescriptions; Family Practice; France; Gastrointestinal Hemorrhage; Humans; Lactones; Middle Aged; Platelet Aggregation Inhibitors; Primary Health Care; Proton Pump Inhibitors; Risk Factors; Sulfones	2004
COX-2 inhibitors--lessons in drug safety. The New England journal of medicine, 2005, Mar-17, Volume: 352, Issue:11 Topics: Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Approval; Gastrointestinal Hemorrhage; Humans; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Publishing; Pyrazoles; Randomized Controlled Trials as Topic; Research Design; Sulfonamides; Sulfones; United States; United States Food and Drug Administration	2005
COX-2 inhibitors--a lesson in unexpected problems. The New England journal of medicine, 2005, Mar-17, Volume: 352, Issue:11 Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Approval; Gastrointestinal Hemorrhage; Humans; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones	2005
Prescription channeling of COX-2 inhibitors and traditional nonselective nonsteroidal anti-inflammatory drugs: a population-based case-control study. Arthritis research & therapy, 2005, Volume: 7, Issue:2 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Celecoxib; Confounding Factors, Epidemiologic; Contraindications; Cyclooxygenase 2 Inhibitors; Databases, Factual; Drug Prescriptions; Drug Utilization; Female; Formularies as Topic; Gastritis; Gastrointestinal Hemorrhage; Humans; Insurance Coverage; Insurance, Pharmaceutical Services; Lactones; Logistic Models; Male; Medicine; Middle Aged; Multivariate Analysis; Prevalence; Pyrazoles; Quebec; Risk Factors; Sampling Studies; Sex Factors; Specialization; Sulfonamides; Sulfones	2005
Ischemic colitis associated with rofecoxib. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:5 Topics: Abdominal Pain; Colitis, Ischemic; Colon; Cyclooxygenase Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; Lactones; Low Back Pain; Male; Middle Aged; Rectum; Sulfones	2005
Risks and benefits of COX-2 inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study. Rheumatology (Oxford, England), 2007, Volume: 46, Issue:3 Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Prescriptions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Lactones; Male; Myocardial Infarction; Naproxen; Pyrazoles; Quebec; Retrospective Studies; Risk Assessment; Sulfonamides; Sulfones	2007
Rofecoxib for osteoarthritis and pain. The Medical letter on drugs and therapeutics, 1999, Jul-02, Volume: 41, Issue:1056 Topics: Analgesics; Cyclooxygenase Inhibitors; Diarrhea; Drug Interactions; Dyspepsia; Edema; Enzyme Inhibitors; Gastrointestinal Hemorrhage; Humans; Hypertension; Lactones; Nausea; Osteoarthritis; Pain; Sulfones	1999
Cyclooxygenase-2 inhibitor celecoxib: a possible cause of gastropathy and hypoprothrombinemia. Southern medical journal, 2000, Volume: 93, Issue:9 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthritis; Atrial Fibrillation; Bicarbonates; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrointestinal Hemorrhage; Hip Joint; Humans; Hypoprothrombinemias; Incidence; Intestinal Mucosa; Isoenzymes; Lactones; Male; Membrane Proteins; Mucus; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Warfarin	2000
Upper gastrointestinal toxicity of rofecoxib and naproxen. The New England journal of medicine, 2001, May-03, Volume: 344, Issue:18 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Ethics, Medical; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Lactones; Middle Aged; Misoprostol; Naproxen; Proton Pump Inhibitors; Risk Factors; Sulfones	2001
Severe upper gastrointestinal bleeding during treatment with rofecoxib for osteoarthritis. The American journal of gastroenterology, 2001, Volume: 96, Issue:5 Topics: Aged; Cyclooxygenase Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; Lactones; Osteoarthritis; Severity of Illness Index; Sulfones	2001
Cyclo-oxygenase-2 inhibitors to treat gastrointestinal bleeding. Lancet (London, England), 2001, Nov-03, Volume: 358, Issue:9292 Topics: Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhage; Humans; Hypertension; Kidney; Lactones; Sulfones	2001
Incremental cost-effectiveness analysis comparing rofecoxib with nonselective NSAIDs in osteoarthritis: Ontario Ministry of Health perspective. PharmacoEconomics, 2001, Volume: 19, Issue:10 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Decision Support Techniques; Gastrointestinal Hemorrhage; Humans; Isoenzymes; Lactones; Membrane Proteins; Ontario; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Stomach Ulcer; Sulfones	2001
Celecoxib and rofecoxib. Journal of the American Dental Association (1939), 2001, Volume: 132, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhage; Humans; Lactones; Middle Aged; Peptic Ulcer; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulfones	2001
[Rofecoxib-induced upper gastrointestinal bleeding]. Medicina clinica, 2002, Feb-23, Volume: 118, Issue:6 Topics: Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhage; Humans; Lactones; Sulfones	2002
Gastrointestinal bleeds associated with rofecoxib. Pharmacotherapy, 2002, Volume: 22, Issue:3 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhage; Hematemesis; Humans; Ibuprofen; Lactones; Laminectomy; Male; Melena; Middle Aged; Pain, Postoperative; Sulfones	2002
Rofecoxib: a possible cause of acute colitis. Journal of clinical gastroenterology, 2002, Volume: 34, Issue:4 Topics: Acute Disease; Colitis; Cyclooxygenase Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; Lactones; Low Back Pain; Middle Aged; Sulfones	2002
Up-regulation of COX-2 by inhibition of COX-1 in the rat: a key to NSAID-induced gastric injury. Alimentary pharmacology & therapeutics, 2002, Volume: 16 Suppl 2 Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastrointestinal Hemorrhage; Gastrointestinal Motility; Gene Expression; Indomethacin; Isoenzymes; Lactones; Male; Membrane Proteins; Molecular Sequence Data; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stomach Ulcer; Sulfones; Up-Regulation	2002