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rofecoxib and Dyspepsia

rofecoxib has been researched along with Dyspepsia in 7 studies

Dyspepsia: Impaired digestion, especially after eating.

Research Excerpts

ExcerptRelevanceReference
"To compare patient and physician attitudes to osteoarthritis (OA) treatment with rofecoxib or traditional non-steroidal anti-inflammatory drugs (tNSAIDs)."9.10Experience of rofecoxib in patients with osteoarthritis previously treated with traditional non-steroidal anti-inflammatory drugs in Spain: results of phase 2 of the VICOXX study. ( Aragón, B; Arboleya, LR; de la Figuera, E; Soledad García, M, 2003)
" To test whether COX-2 inhibition with rofecoxib would have greater GI tolerability than nonselective COX-1 and COX-2 inhibition, we compared the incidences of (1) treatment discontinuations for GI adverse events (AEs) and (2) prespecified dyspeptic-type GI AEs among patients with osteoarthritis treated with rofecoxib vs NSAIDs."8.80Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis. ( Bolognese, JA; Harper, SE; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL, 2000)
"To compare patient and physician attitudes to osteoarthritis (OA) treatment with rofecoxib or traditional non-steroidal anti-inflammatory drugs (tNSAIDs)."5.10Experience of rofecoxib in patients with osteoarthritis previously treated with traditional non-steroidal anti-inflammatory drugs in Spain: results of phase 2 of the VICOXX study. ( Aragón, B; Arboleya, LR; de la Figuera, E; Soledad García, M, 2003)
" To test whether COX-2 inhibition with rofecoxib would have greater GI tolerability than nonselective COX-1 and COX-2 inhibition, we compared the incidences of (1) treatment discontinuations for GI adverse events (AEs) and (2) prespecified dyspeptic-type GI AEs among patients with osteoarthritis treated with rofecoxib vs NSAIDs."4.80Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis. ( Bolognese, JA; Harper, SE; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL, 2000)
" Dyspepsia and nausea were the most frequently reported adverse events."1.32Safety profile of rofecoxib as used in general practice in England: results of a prescription-event monitoring study. ( Layton, D; Riley, J; Shakir, SA; Wilton, LV, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van der Bijl, P2
Layton, D1
Riley, J1
Wilton, LV1
Shakir, SA1
Arboleya, LR1
de la Figuera, E1
Soledad García, M1
Aragón, B1
Celik, JB1
Tuncer, S1
Reisli, R1
Sarkilar, G1
Celik, C1
Akyürek, C1
Hollenz, M1
Labenz, J1
Watson, DJ1
Harper, SE1
Zhao, PL1
Quan, H1
Bolognese, JA1
Simon, TJ1

Reviews

2 reviews available for rofecoxib and Dyspepsia

ArticleYear
Non-steroidal anti-inflammatory drugs in orofacial pain management--an update.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2002, Volume: 57, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Drug Interactions; Dy

2002
Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis.
    Archives of internal medicine, 2000, Oct-23, Volume: 160, Issue:19

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Clinical Tr

2000

Trials

2 trials available for rofecoxib and Dyspepsia

ArticleYear
Experience of rofecoxib in patients with osteoarthritis previously treated with traditional non-steroidal anti-inflammatory drugs in Spain: results of phase 2 of the VICOXX study.
    Current medical research and opinion, 2003, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dyspeps

2003
A comparative study of the effect of rofecoxib (a COX 2 inhibitor) and naproxen sodium on analgesic requirements after abdominal hysterectomy.
    Archives of gynecology and obstetrics, 2003, Volume: 268, Issue:4

    Topics: Adult; Analgesia; Cyclooxygenase Inhibitors; Dyspepsia; Female; Gastrointestinal Diseases; Heartburn

2003

Other Studies

3 other studies available for rofecoxib and Dyspepsia

ArticleYear
Safety profile of rofecoxib as used in general practice in England: results of a prescription-event monitoring study.
    British journal of clinical pharmacology, 2003, Volume: 55, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inh

2003
[Gastrointestinal complications under NSAID treatment in the doctor's office].
    MMW Fortschritte der Medizin, 2004, Dec-02, Volume: 146, Issue:49

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Dicl

2004
Rofecoxib for osteoarthritis and pain.
    The Medical letter on drugs and therapeutics, 1999, Jul-02, Volume: 41, Issue:1056

    Topics: Analgesics; Cyclooxygenase Inhibitors; Diarrhea; Drug Interactions; Dyspepsia; Edema; Enzyme Inhibit

1999