Page last updated: 2024-11-04

rofecoxib and Dysmenorrhea

rofecoxib has been researched along with Dysmenorrhea in 11 studies

Dysmenorrhea: Painful menstruation.

Research Excerpts

ExcerptRelevanceReference
"To investigate the efficacy of single daily doses of rofecoxib, a selective inhibitor of cyclooxygenase-2, in dysmenorrhea."9.10Dysmenorrhea treatment with a single daily dose of rofecoxib. ( Kurban, Y; Sahin, I; Saraçoğlu, F; Türkkani, B, 2003)
"To determine whether rofecoxib is effective for treating primary dysmenorrhea and whether cyclooxygenase-2 is involved in the pathophysiology of primary dysmenorrhea."9.09Rofecoxib, a specific cyclooxygenase-2 inhibitor, in primary dysmenorrhea: a randomized controlled trial. ( Cantu, N; Daniels, SE; Kotey, P; Morrison, BW; Seidenberg, B, 1999)
"Rofecoxib and diclofenac potassium, when taken in recommended doses, were equally effective in alleviating pain associated with primary dysmenorrhea."5.13The effect of three cyclo-oxygenase inhibitors on intensity of primary dysmenorrheic pain. ( Chantler, I; Fuller, A; Mitchell, D, 2008)
"To investigate the efficacy of single daily doses of rofecoxib, a selective inhibitor of cyclooxygenase-2, in dysmenorrhea."5.10Dysmenorrhea treatment with a single daily dose of rofecoxib. ( Kurban, Y; Sahin, I; Saraçoğlu, F; Türkkani, B, 2003)
"To determine whether rofecoxib is effective for treating primary dysmenorrhea and whether cyclooxygenase-2 is involved in the pathophysiology of primary dysmenorrhea."5.09Rofecoxib, a specific cyclooxygenase-2 inhibitor, in primary dysmenorrhea: a randomized controlled trial. ( Cantu, N; Daniels, SE; Kotey, P; Morrison, BW; Seidenberg, B, 1999)
"Rofecoxib, used for dysmenorrhea, caused a herpetiform fixed drug eruption predominantly involving the lips with classic clinical and histological findings in a red-brown lesion on the dorsal hand."3.71Fixed drug eruption to rofecoxib. ( Florentino, FT; Gilliam, AC; Nedorost, ST, 2002)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's8 (72.73)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nedorost, ST1
Florentino, FT1
Gilliam, AC1
Sahin, I1
Saraçoğlu, F1
Kurban, Y1
Türkkani, B1
Bitner, M1
Kattenhorn, J1
Hatfield, C1
Gao, J1
Kellstein, D1
Yodfat, Y1
Chantler, I1
Mitchell, D1
Fuller, A1
Scott, LJ1
Lamb, HM1
Morrison, BW1
Daniels, SE1
Kotey, P1
Cantu, N1
Seidenberg, B1
Miller, JL1
Sirakov, M1
FitzGerald, GA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Effect of a Vaginal Ring With Meloxicam on Primary Dysmenorrhea in Women of Childbearing Age[NCT02255045]Phase 2/Phase 368 participants (Actual)Interventional2014-06-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for rofecoxib and Dysmenorrhea

ArticleYear
[Is there a future for COX-2 inhibitors?].
    Harefuah, 2004, Volume: 143, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2; Cyclooxygenase 2 I

2004
Rofecoxib.
    Drugs, 1999, Volume: 58, Issue:3

    Topics: Analgesics; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug Interactions; Dysmenorrhea; En

1999
[VIOXX--a new world without pain].
    Akusherstvo i ginekologiia, 2001, Volume: 40 Suppl 5

    Topics: Adult; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; Lactones; Pain; Sulfones

2001

Trials

4 trials available for rofecoxib and Dysmenorrhea

ArticleYear
Dysmenorrhea treatment with a single daily dose of rofecoxib.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2003, Volume: 83, Issue:3

    Topics: Administration, Oral; Adult; Analysis of Variance; Chi-Square Distribution; Cross-Over Studies; Cycl

2003
Efficacy and tolerability of lumiracoxib in the treatment of primary dysmenorrhoea.
    International journal of clinical practice, 2004, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase

2004
The effect of three cyclo-oxygenase inhibitors on intensity of primary dysmenorrheic pain.
    The Clinical journal of pain, 2008, Volume: 24, Issue:1

    Topics: Adult; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationshi

2008
Rofecoxib, a specific cyclooxygenase-2 inhibitor, in primary dysmenorrhea: a randomized controlled trial.
    Obstetrics and gynecology, 1999, Volume: 94, Issue:4

    Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; Lactones; Pain; Sulfones

1999

Other Studies

4 other studies available for rofecoxib and Dysmenorrhea

ArticleYear
Fixed drug eruption to rofecoxib.
    Cutis, 2002, Volume: 70, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Dysmenorrhea; Erythema; Female; Huma

2002
Second selective COX-2 inhibitor receives marketing approval.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jul-01, Volume: 56, Issue:13

    Topics: Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors;

1999
Nonsteroidal anti-inflammatory drugs, coxibs, and cardio-renal physiology: a mechanism-based approach.
    The American journal of cardiology, 2002, Mar-21, Volume: 89, Issue:6A

    Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Syste

2002
[New indication for selective COX-2 inhibitors. Now also approve for acute pain].
    MMW Fortschritte der Medizin, 2002, Mar-07, Volume: 144, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug A

2002