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rofecoxib and Colonic Neoplasms

rofecoxib has been researched along with Colonic Neoplasms in 11 studies

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
" Herein, we report the synthesis of carborane-containing derivatives of rofecoxib that display remarkable cytotoxic or cytostatic activity in the micromolar range with excellent selectivity for melanoma and colon cancer cell lines over normal cells."7.96Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells. ( Buzharevski, A; Hey-Hawkins, E; Laube, M; Lönnecke, P; Maksimović-Ivanić, D; Mijatović, S; Murganić, B; Neumann, W; Paskaš, S; Pietzsch, J; Sárosi, MB, 2020)
" Herein, we report the synthesis of carborane-containing derivatives of rofecoxib that display remarkable cytotoxic or cytostatic activity in the micromolar range with excellent selectivity for melanoma and colon cancer cell lines over normal cells."3.96Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells. ( Buzharevski, A; Hey-Hawkins, E; Laube, M; Lönnecke, P; Maksimović-Ivanić, D; Mijatović, S; Murganić, B; Neumann, W; Paskaš, S; Pietzsch, J; Sárosi, MB, 2020)
"Rofecoxib in lower doses had the same effect on adenomas (p < 0."1.33Cyclooxygenase-2 inhibition in colon experimental carcinogenesis. ( Amengual Antich, I; Gamundí Gamundí, A; Ibarra de la Rosa, J; Noguera Aguilar, JF; Plaza Martínez, A; Pujol Tugores, JJ; Tortajada Collado, C, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Bhardwaj, A1
Kaur, J1
Sharma, SK1
Huang, Z1
Wuest, F1
Knaus, EE1
Buzharevski, A1
Paskaš, S1
Sárosi, MB1
Laube, M1
Lönnecke, P1
Neumann, W1
Murganić, B1
Mijatović, S1
Maksimović-Ivanić, D1
Pietzsch, J1
Hey-Hawkins, E1
Dovizio, M1
Maier, TJ2
Alberti, S1
Di Francesco, L1
Marcantoni, E1
Münch, G1
John, CM1
Suess, B1
Sgambato, A1
Steinhilber, D1
Patrignani, P1
Zhang, Y1
Hoda, MN1
Zheng, X1
Li, W1
Luo, P1
Maddipati, KR1
Seki, T1
Ergul, A1
Wang, MH1
Evans, JF1
Noguera Aguilar, JF2
Plaza Martínez, A2
Amengual Antich, I2
Morón Canis, JM1
Tortajada Collado, C2
Pujol Tugores, JJ2
Thompson, CA1
Janssen, A1
Schmidt, R1
Geisslinger, G1
Grösch, S1
Ibarra de la Rosa, J1
Gamundí Gamundí, A1
Soh, JW1
Kazi, JU1
Li, H1
Thompson, WJ1
Weinstein, IB1
Ziegler, J1

Other Studies

11 other studies available for rofecoxib and Colonic Neoplasms

ArticleYear
Hybrid fluorescent conjugates of COX-2 inhibitors: search for a COX-2 isozyme imaging cancer biomarker.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Acridines; Acridones; Biomarkers, Tumor; Celecoxib; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygen

2013
Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells.
    Scientific reports, 2020, 03-16, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Boron Compounds; Carcinogenesis; Cell Line, Tumor; Colonic Neoplasms; Cycloox

2020
Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells.
    Molecular pharmacology, 2013, Volume: 84, Issue:1

    Topics: Binding Sites; Blood Platelets; Cell Communication; Cell Line, Tumor; Colonic Neoplasms; Cyclin B1;

2013
Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Sep-15, Volume: 307, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Ischemia; Cell Line, Tumor; Cell Prol

2014
Rofecoxib (Vioxx), a specific cyclooxygenase-2 inhibitor, is chemopreventive in a mouse model of colon cancer.
    American journal of clinical oncology, 2003, Volume: 26, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Co

2003
Influence of rofecoxib on experimental colonic carcinogenesis in rats.
    Revista espanola de enfermedades digestivas, 2004, Volume: 96, Issue:10

    Topics: 1,2-Dimethylhydrazine; Animals; Aspirin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxyg

2004
COX-2 inhibitors still eyed for cancer prevention.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2005, May-01, Volume: 62, Issue:9

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Celecoxib; Colonic Neoplasms; Cycl

2005
Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:10

    Topics: Adenomatous Polyposis Coli Protein; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents

2005
Cyclooxygenase-2 inhibition in colon experimental carcinogenesis.
    Revista espanola de enfermedades digestivas, 2005, Volume: 97, Issue:9

    Topics: 1,2-Dimethylhydrazine; Animals; Aspirin; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhib

2005
Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.
    Molecular carcinogenesis, 2008, Volume: 47, Issue:7

    Topics: Apoptosis; Celecoxib; Cell Adhesion Molecules; Cell Proliferation; Colonic Neoplasms; Cyclic GMP; Cy

2008
Early trials probe COX-2 inhibitors' cancer-fighting potential.
    Journal of the National Cancer Institute, 1999, Jul-21, Volume: 91, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials as Topic; Colonic Neoplasms; Cyc

1999