rofecoxib has been researched along with Colitis in 8 studies
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have evaluated the efficacy of the selective cyclo-oxygenase (COX)-2 inhibitor, rofecoxib, for the prevention of experimental colitis." | 7.73 | The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice. ( Alarcón de la Lastra, C; Martín, AR; Villegas, I, 2005) |
| "A potential signal of 'colitis' was identified when rofecoxib was compared with the rest of the database, IRR 5." | 7.72 | Identification and evaluation of a possible signal of exacerbation of colitis during rofecoxib treatment, using Prescription-Event Monitoring data. ( Heeley, E; Layton, D; Shakir, SA, 2004) |
| "Acetic acid treatment caused haemorrhagic diarrhoea and weight loss in rats." | 5.33 | The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats. ( Arafa, M; El-Medany, A; Mahgoub, A; Morsi, M; Mustafa, A, 2005) |
| "We have evaluated the efficacy of the selective cyclo-oxygenase (COX)-2 inhibitor, rofecoxib, for the prevention of experimental colitis." | 3.73 | The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice. ( Alarcón de la Lastra, C; Martín, AR; Villegas, I, 2005) |
| "Rats treated with rofecoxib, aminoguanidine hydrochloride and their combinations reduced the inflammation, acute colonic damage produced by TNBS as verified by macroscopic changes in colon." | 1.34 | Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats. ( Dudhgaonkar, SP; Kataria, M; Kumar, D; Raviprakash, V; Tandan, SK, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hegazi, RA | 1 |
| Mady, HH | 1 |
| Melhem, MF | 1 |
| Sepulveda, AR | 1 |
| Mohi, M | 1 |
| Kandil, HM | 1 |
| Martín, AR | 2 |
| Villegas, I | 2 |
| La Casa, C | 1 |
| Alarcón de la Lastra, C | 2 |
| Layton, D | 1 |
| Heeley, E | 1 |
| Shakir, SA | 1 |
| El-Medany, A | 1 |
| Mahgoub, A | 1 |
| Mustafa, A | 1 |
| Arafa, M | 1 |
| Morsi, M | 1 |
| Skinn, AC | 1 |
| Vergnolle, N | 1 |
| Zamuner, SR | 1 |
| Wallace, JL | 1 |
| Cellars, L | 1 |
| MacNaughton, WK | 1 |
| Sherman, PM | 1 |
| Dudhgaonkar, SP | 1 |
| Tandan, SK | 1 |
| Kumar, D | 1 |
| Raviprakash, V | 1 |
| Kataria, M | 1 |
| Freitas, J | 1 |
| Farricha, V | 1 |
| Nascimento, I | 1 |
| Borralho, P | 1 |
| Paramés, A | 1 |
8 other studies available for rofecoxib and Colitis
| Article | Year |
|---|---|
Celecoxib and rofecoxib potentiate chronic colitis and premalignant changes in interleukin 10 knockout mice.
Topics: Animals; Celecoxib; Colitis; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal | 2003 |
The cyclo-oxygenase-2 inhibitor, rofecoxib, attenuates mucosal damage due to colitis induced by trinitrobenzene sulphonic acid in rats.
Topics: Animals; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Res | 2003 |
Identification and evaluation of a possible signal of exacerbation of colitis during rofecoxib treatment, using Prescription-Event Monitoring data.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Co | 2004 |
The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Lactones; Male; Pyrazoles; Rats | 2005 |
The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice.
Topics: Animals; Colitis; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dextran Sulfate; Dinoprostone; Immuno | 2005 |
Citrobacter rodentium infection causes iNOS-independent intestinal epithelial dysfunction in mice.
Topics: Animals; Bacterial Translocation; Carbachol; Cell Membrane Permeability; Cholinergic Agonists; Citro | 2006 |
Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats.
Topics: Animals; Catalase; Colitis; Colon; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Comb | 2007 |
Rofecoxib: a possible cause of acute colitis.
Topics: Acute Disease; Colitis; Cyclooxygenase Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; Lact | 2002 |