Page last updated: 2024-11-04

rofecoxib and Cardiomegaly

rofecoxib has been researched along with Cardiomegaly in 4 studies

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Rofecoxib also reduced cardiac hypertrophy."5.33Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005)
"Rofecoxib also reduced cardiac hypertrophy."1.33Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Streicher, JM1
Kamei, K1
Ishikawa, TO1
Herschman, H1
Wang, Y1
Wang, BH1
Bertucci, MC1
Ma, JY1
Adrahtas, A1
Cheung, RY1
Krum, H1
LaPointe, MC1
Mendez, M1
Leung, A1
Tao, Z1
Yang, XP1
Wu, R1
Laplante, MA1
de Champlain, J1

Other Studies

4 other studies available for rofecoxib and Cardiomegaly

ArticleYear
Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice.
    Journal of molecular and cellular cardiology, 2010, Volume: 49, Issue:1

    Topics: Animals; Cardiomegaly; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Heart Failure; Heart Ventricle

2010
Celecoxib, but not rofecoxib or naproxen, attenuates cardiac hypertrophy and fibrosis induced in vitro by angiotensin and aldosterone.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:9

    Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Car

2010
Inhibition of cyclooxygenase-2 improves cardiac function after myocardial infarction in the mouse.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:4

    Topics: Animals; Cardiomegaly; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib

2004
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cult

2005