Page last updated: 2024-11-04

rofecoxib and Body Weight

rofecoxib has been researched along with Body Weight in 9 studies

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" In the present study, we examined the effect of various COX inhibitors on gastric ulcerogenic and acid secretory responses following daily exposure of the stomach to iodoacetamide (IA) and investigated the role for COX isozyme in gastric protection under subchronic mucosal irritation."3.72Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach. ( Hayashi, Y; Murakami, M; Takeeda, M; Takeuchi, K; Yamato, M, 2004)
"Quinolinic acid is an endogenous excitotoxin that causes neurotoxicity in diverse areas of the brain and produces motor dysfunction."1.36Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats. ( Kalonia, H; Kumar, A; Kumar, P; Nehru, B, 2010)
"Quinolinic acid (QA) is a well-known excitotoxic agent that could induce behavioral, morphological and biochemical alterations similar with symptoms of Huntington's disease (HD), by stimulating NMDA receptors."1.35Effects of caffeic acid, rofecoxib, and their combination against quinolinic acid-induced behavioral alterations and disruption in glutathione redox status. ( Kalonia, H; Kumar, A; Kumar, P; Nehru, B, 2009)
"In indomethacin and rofecoxib-treated gerbils, the following results were obtained in H pylori-infected group vs H pylori-eradicated group respectively: hyperplasia area of the stomach (mm2): 82."1.33Eradication of Helicobacter pylori significantly reduced gastric damage in nonsteroidal anti-inflammatory drug-treated Mongolian gerbils. ( Chang, CC; Chen, SH; Fang, CL; Hsieh, CR; Lien, GS; Lou, HY; Pan, S, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalonia, H2
Kumar, P2
Kumar, A2
Nehru, B2
Schwartz, JI1
Vandormael, K1
Malice, MP1
Kalyani, RN1
Lasseter, KC1
Holmes, GB1
Gertz, BJ1
Gottesdiener, KM1
Laurenzi, M1
Redfern, KJ1
Brune, K1
Höcherl, K1
Endemann, D1
Kammerl, MC1
Grobecker, HF1
Kurtz, A1
Takeeda, M1
Hayashi, Y1
Yamato, M1
Murakami, M1
Takeuchi, K1
Norflus, F1
Nanje, A1
Gutekunst, CA1
Shi, G1
Cohen, J1
Bejarano, M1
Fox, J1
Ferrante, RJ1
Hersch, SM1
Chang, CC1
Chen, SH1
Lien, GS1
Lou, HY1
Hsieh, CR1
Fang, CL1
Pan, S1
Jia, Q1
Pestka, JJ1
Fei, SJ1
Xiao, SD1
Peng, YS1
Chen, XY1
Shi, Y1

Trials

1 trial available for rofecoxib and Body Weight

ArticleYear
Comparison of rofecoxib, celecoxib, and naproxen on renal function in elderly subjects receiving a normal-salt diet.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:1

    Topics: Aged; Aged, 80 and over; Blood Pressure; Body Weight; Celecoxib; Creatinine; Cyclooxygenase Inhibito

2002

Other Studies

8 other studies available for rofecoxib and Body Weight

ArticleYear
Effects of caffeic acid, rofecoxib, and their combination against quinolinic acid-induced behavioral alterations and disruption in glutathione redox status.
    Neuroscience bulletin, 2009, Volume: 25, Issue:6

    Topics: Animals; Body Weight; Caffeic Acids; Corpus Striatum; Cyclooxygenase 2 Inhibitors; Disease Models, A

2009
Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats.
    Neurotoxicology, 2010, Volume: 31, Issue:2

    Topics: Animals; Ataxia; Body Weight; Cell Survival; Corpus Striatum; Cyclooxygenase 2 Inhibitors; Lactones;

2010
Cyclo-oxygenase-2 inhibition increases blood pressure in rats.
    British journal of pharmacology, 2002, Volume: 136, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Actins; Aldosterone; Animals; Anti-Inflammatory Agents, Non-Steroidal;

2002
Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 2

    Topics: Administration, Oral; Animals; Body Weight; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyg

2004
Anti-inflammatory treatment with acetylsalicylate or rofecoxib is not neuroprotective in Huntington's disease transgenic mice.
    Neurobiology of disease, 2004, Volume: 17, Issue:2

    Topics: Acoustic Stimulation; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; As

2004
Eradication of Helicobacter pylori significantly reduced gastric damage in nonsteroidal anti-inflammatory drug-treated Mongolian gerbils.
    World journal of gastroenterology, 2005, Jan-07, Volume: 11, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Chronic Diseas

2005
Role of cyclooxygenase-2 in deoxynivalenol-induced immunoglobulin a nephropathy.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2005, Volume: 43, Issue:5

    Topics: Analysis of Variance; Animals; Body Weight; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxyg

2005
Chemopreventive effects of rofecoxib and folic acid on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.
    Chinese journal of digestive diseases, 2006, Volume: 7, Issue:3

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Cell Proliferation; Folic Acid; Gastr

2006