rofecoxib has been researched along with Barrett Epithelium in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effects of aspirin and rofecoxib when administered with esomeprazole on prostaglandin E(2) production, cyclo-oxygenase-2 expression and proliferating cell nuclear antigen expression in patients with Barrett's oesophagus." | 2.72 | The effects of esomeprazole combined with aspirin or rofecoxib on prostaglandin E2 production in patients with Barrett's oesophagus. ( Kaur, B; Levine, D; Sood, S; Traxler, B; Triadafilopoulos, G; Weston, A, 2006) |
| "Biopsy specimens of esophagus, Barrett's esophagus, and duodenum were obtained at baseline from 12 patients and were compared with biopsy specimens obtained after 10 days of therapy with rofecoxib 25 mg orally daily." | 2.70 | Rofecoxib inhibits cyclooxygenase 2 expression and activity and reduces cell proliferation in Barrett's esophagus. ( Iravani, M; Kaur, BS; Khamnehei, N; Lin, O; Namburu, SS; Triadafilopoulos, G, 2002) |
| "Carcinogenesis in Barrett's esophagus (BE) is associated with an increased expression of cyclooxygenase (COX) 2." | 1.31 | Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus. ( Anderson, MA; Burgart, LJ; Buttar, NS; Krishnadath, KK; Leontovich, O; Lutzke, LS; Pacifico, RJ; Wang, KK; Westcott, JY, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Triadafilopoulos, G | 2 |
| Kaur, B | 1 |
| Sood, S | 1 |
| Traxler, B | 1 |
| Levine, D | 1 |
| Weston, A | 1 |
| Lanas, A | 1 |
| Ortego, J | 1 |
| Sopeña, F | 1 |
| Alcedo, J | 1 |
| Barrio, E | 1 |
| Bujanda, L | 1 |
| Cosme, A | 1 |
| Bajador, E | 1 |
| Parra-Blanco, A | 1 |
| Ferrandez, A | 1 |
| Piazuelo, E | 1 |
| Quintero, E | 1 |
| Pique, JM | 1 |
| Buttar, NS | 1 |
| Wang, KK | 1 |
| Leontovich, O | 1 |
| Westcott, JY | 1 |
| Pacifico, RJ | 1 |
| Anderson, MA | 1 |
| Krishnadath, KK | 1 |
| Lutzke, LS | 1 |
| Burgart, LJ | 1 |
| Kaur, BS | 1 |
| Khamnehei, N | 1 |
| Iravani, M | 1 |
| Namburu, SS | 1 |
| Lin, O | 1 |
3 trials available for rofecoxib and Barrett Epithelium
| Article | Year |
|---|---|
The effects of esomeprazole combined with aspirin or rofecoxib on prostaglandin E2 production in patients with Barrett's oesophagus.
Topics: Adult; Aged; Aspirin; Barrett Esophagus; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhi | 2006 |
Effects of long-term cyclo-oxygenase 2 selective and acid inhibition on Barrett's oesophagus.
Topics: Apoptosis; Barrett Esophagus; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combina | 2007 |
Rofecoxib inhibits cyclooxygenase 2 expression and activity and reduces cell proliferation in Barrett's esophagus.
Topics: Aged; Barrett Esophagus; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenas | 2002 |
1 other study available for rofecoxib and Barrett Epithelium
| Article | Year |
|---|---|
Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus.
Topics: Adenocarcinoma; Animals; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxyg | 2002 |