Page last updated: 2024-11-04

rofecoxib and Arthralgia

rofecoxib has been researched along with Arthralgia in 11 studies

Arthralgia: Pain in the joint.

Research Excerpts

ExcerptRelevanceReference
" This safety study compared the GI tolerability, the blood pressure (BP) profile and the incidence of oedema with lumiracoxib and rofecoxib in the treatment of OA."9.13A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients. ( Krammer, G; Stricker, K; Yu, S, 2008)
"To report a case of rofecoxib (Vioxx)-associated Stevens-Johnson syndrome with corneal and conjunctival changes."7.72A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes. ( Abelson, M; Barazi, M; Butrus, S; Goldberg, D; Panigrahi, D, 2004)
" This safety study compared the GI tolerability, the blood pressure (BP) profile and the incidence of oedema with lumiracoxib and rofecoxib in the treatment of OA."5.13A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients. ( Krammer, G; Stricker, K; Yu, S, 2008)
"Rofecoxib appears to control arthralgia in almost two-thirds of inflammatory bowel disease patients."5.11Rofecoxib and early relapse of inflammatory bowel disease: an open-label trial. ( Biancone, L; Emerenziani, S; Fina, D; Geremia, A; Pallone, F; Petruzziello, C; Tosti, C, 2004)
"To report a case of rofecoxib (Vioxx)-associated Stevens-Johnson syndrome with corneal and conjunctival changes."3.72A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes. ( Abelson, M; Barazi, M; Butrus, S; Goldberg, D; Panigrahi, D, 2004)
"Rofecoxib treatment, with its faster onset of OA efficacy and lower rates of related discontinuations, might provide efficacy advantages in the treatment of OA pain."2.71Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials. ( Battisti, WP; Geba, GP; Katz, NP; Kivitz, AJ; Matsumoto, AK; Polis, AB; Weaver, AL, 2004)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's9 (81.82)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ross, JS1
Krumholz, HM1
Angeby-Möller, K1
Berge, OG1
Hamers, FP1
Stricker, K1
Yu, S1
Krammer, G1
Déciga-Campos, M1
López, UG1
Reval, MI1
López-Muñoz, FJ1
Reinisch, W1
Miehsler, W1
Dejaco, C1
Harrer, M1
Waldhoer, T1
Lichtenberger, C1
Vogelsang, H1
Biancone, L1
Tosti, C1
Geremia, A1
Fina, D1
Petruzziello, C1
Emerenziani, S1
Pallone, F1
Goldberg, D1
Panigrahi, D1
Barazi, M1
Abelson, M1
Butrus, S1
Battisti, WP1
Katz, NP1
Weaver, AL1
Matsumoto, AK1
Kivitz, AJ1
Polis, AB1
Geba, GP1
Wilcox, GM1
Mattia, AR1
Bove, SE1
Laemont, KD1
Brooker, RM1
Osborn, MN1
Sanchez, BM1
Guzman, RE1
Hook, KE1
Juneau, PL1
Connor, JR1
Kilgore, KS1
Miller, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A 6-Week Multicenter, Randomized, Double-Blind, Double-Dummy, Active-Controlled Parallel Group Clinical Saftey Study to Evaluate Incidence of Predefined Gastrointestinal Adverse Events and Peripheral Edema in Subjects With Primary Osteoarthritis Treated W[NCT00637949]Phase 3309 participants (Actual)Interventional2000-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for rofecoxib and Arthralgia

ArticleYear
A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients.
    BMC musculoskeletal disorders, 2008, Sep-08, Volume: 9

    Topics: Aged; Arthralgia; Blood Pressure; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationshi

2008
An open-label trial of the selective cyclo-oxygenase-2 inhibitor, rofecoxib, in inflammatory bowel disease-associated peripheral arthritis and arthralgia.
    Alimentary pharmacology & therapeutics, 2003, Jun-01, Volume: 17, Issue:11

    Topics: Adult; Aged; Arthralgia; Arthritis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase In

2003
Rofecoxib and early relapse of inflammatory bowel disease: an open-label trial.
    Alimentary pharmacology & therapeutics, 2004, Apr-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Colitis, Ulcerative; Crohn Disease

2004
Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials.
    The journal of pain, 2004, Volume: 5, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Butano

2004

Other Studies

7 other studies available for rofecoxib and Arthralgia

ArticleYear
Bringing Vioxx back to market.
    BMJ (Clinical research ed.), 2018, 01-25, Volume: 360

    Topics: Arthralgia; Drug Approval; Hemophilia A; Humans; Lactones; Safety-Based Drug Withdrawals; Sulfones

2018
Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: effects of morphine and rofecoxib.
    Journal of neuroscience methods, 2008, Sep-15, Volume: 174, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Animals; Ankle Joint; Anti-Inflammatory Agents; Arthralgia; Arthriti

2008
Enhancement of antinociception by co-administration of an opioid drug (morphine) and a preferential cyclooxygenase-2 inhibitor (rofecoxib) in rats.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arthralgia; Cyclooxygenase 2; Cycloox

2003
A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes.
    Cornea, 2004, Volume: 23, Issue:7

    Topics: Arthralgia; Conjunctiva; Cornea; Cyclooxygenase Inhibitors; Female; Humans; Lactones; Middle Aged; S

2004
Rofecoxib and inflammatory bowel disease: clinical and pathologic observations.
    Journal of clinical gastroenterology, 2005, Volume: 39, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Biopsy; Colitis, Ulcerative; Colon

2005
Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia.
    Osteoarthritis and cartilage, 2006, Volume: 14, Issue:10

    Topics: Amines; Analgesics; Animals; Arthralgia; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; D

2006
Decisions loom on selective COX-2 inhibitors.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jan-15, Volume: 56, Issue:2

    Topics: Arthralgia; Arthritis; Celecoxib; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Humans; Lacto

1999