rofecoxib has been researched along with Arteriosclerosis in 3 studies
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rofecoxib treatment did not inhibit platelet thromboxane production, a COX-1-mediated process, but it significantly reduced the urinary prostacyclin metabolite 2,3-dinor-6-keto-PGF1alpha." | 1.31 | Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. ( Babaev, VR; Burleigh, ME; Fazio, S; Gautam, S; Harris, RC; Linton, MF; Marnett, LJ; Morrow, JD; Oates, JA; Riendeau, D, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Egan, KM | 1 |
| Lawson, JA | 1 |
| Fries, S | 1 |
| Koller, B | 1 |
| Rader, DJ | 1 |
| Smyth, EM | 1 |
| Fitzgerald, GA | 1 |
| Burleigh, ME | 2 |
| Babaev, VR | 2 |
| Yancey, PG | 1 |
| Major, AS | 1 |
| McCaleb, JL | 1 |
| Oates, JA | 2 |
| Morrow, JD | 2 |
| Fazio, S | 2 |
| Linton, MF | 2 |
| Harris, RC | 1 |
| Gautam, S | 1 |
| Riendeau, D | 1 |
| Marnett, LJ | 1 |
3 other studies available for rofecoxib and Arteriosclerosis
| Article | Year |
|---|---|
COX-2-derived prostacyclin confers atheroprotection on female mice.
Topics: Animals; Antioxidants; Arteriosclerosis; Cardiovascular Diseases; Cells, Cultured; Cyclooxygenase 2; | 2004 |
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Cells, Cultured; Chemokine CCL2; Cyclooxygenase | 2005 |
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice.
Topics: Animals; Arteriosclerosis; Blood Platelets; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxyg | 2002 |