rofecoxib has been researched along with Angiogenesis, Pathologic in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the nonselective and relatively inexpensive nonsteroidal anti-inflammatory drug ibuprofen would be effective in inhibiting colorectal cancer and might improve mortality in a mouse model." | 7.73 | Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer. ( Albert, A; Chang, AJ; Liu, TC; Sangha, S; Wolfe, MM; Yao, M; Zhou, W, 2005) |
| "A phase II trial was initiated to analyze the activity of continuously administered pioglitazone and rofecoxib combined with low-dose chemotherapy (capecitabine or temozolomide) in patients with high-grade gliomas (glioblastoma or anaplastic glioma)." | 5.12 | Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study. ( Baumgart, U; Bogdahn, U; Hau, P; Hirschmann, B; Kunz-Schughart, L; Muhleisen, H; Reichle, A; Ruemmele, P; Steinbrecher, A; Weimann, E, 2007) |
| "To determine whether the nonselective and relatively inexpensive nonsteroidal anti-inflammatory drug ibuprofen would be effective in inhibiting colorectal cancer and might improve mortality in a mouse model." | 3.73 | Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer. ( Albert, A; Chang, AJ; Liu, TC; Sangha, S; Wolfe, MM; Yao, M; Zhou, W, 2005) |
| "In co-culture system, whose gastric cancer cells expressed positive COX-2, ω-6 could increase angiogenesis of gastric cancer cells(P<0." | 1.46 | [Effect of polyunsaturated fatty acids ω-3 and ω-6 on angiogenesis formation in human gastric cancer]. ( Chen, Q; Chen, X; Guo, Q; Guo, T; Li, Y; Ma, J; Ma, Y; Qi, J; Su, H; Zhao, X, 2017) |
| "Rofecoxib (30 mg/kg) was administered orally to animals every day for eight weeks." | 1.32 | [Effects of rofecoxib on angiogenesis of pancreatic cancer xenograft in nude mice]. ( Liu, CL; Tang, CW; Wang, CH; Zhou, XC, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (90.91) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, J | 1 |
| Ma, Y | 1 |
| Guo, T | 1 |
| Chen, Q | 1 |
| Li, Y | 1 |
| Su, H | 1 |
| Chen, X | 1 |
| Zhao, X | 1 |
| Guo, Q | 1 |
| Qi, J | 1 |
| Woods, JM | 1 |
| Mogollon, A | 1 |
| Amin, MA | 1 |
| Martinez, RJ | 1 |
| Koch, AE | 1 |
| Zhou, XC | 1 |
| Tang, CW | 1 |
| Liu, CL | 1 |
| Wang, CH | 1 |
| Gately, S | 1 |
| Li, WW | 1 |
| Tuettenberg, J | 1 |
| Grobholz, R | 1 |
| Korn, T | 1 |
| Wenz, F | 1 |
| Erber, R | 1 |
| Vajkoczy, P | 1 |
| Yao, M | 1 |
| Zhou, W | 1 |
| Sangha, S | 1 |
| Albert, A | 1 |
| Chang, AJ | 1 |
| Liu, TC | 1 |
| Wolfe, MM | 1 |
| Kasper, B | 1 |
| Ho, AD | 1 |
| Egerer, G | 1 |
| Grösch, S | 1 |
| Maier, TJ | 1 |
| Schiffmann, S | 1 |
| Geisslinger, G | 1 |
| Chalmers, CR | 1 |
| Wilson, DJ | 1 |
| Ward, J | 1 |
| Robinson, PJ | 1 |
| Toogood, GJ | 1 |
| Hull, MA | 1 |
| Hau, P | 1 |
| Kunz-Schughart, L | 1 |
| Bogdahn, U | 1 |
| Baumgart, U | 1 |
| Hirschmann, B | 1 |
| Weimann, E | 1 |
| Muhleisen, H | 1 |
| Ruemmele, P | 1 |
| Steinbrecher, A | 1 |
| Reichle, A | 1 |
| Dicker, AP | 1 |
| Williams, TL | 1 |
| Grant, DS | 1 |
2 reviews available for rofecoxib and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Celecoxib; Cell Movement; Cyclooxygenase | 2004 |
Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors.
Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Anti-Inflammatory Agents, N | 2006 |
1 trial available for rofecoxib and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabin | 2007 |
8 other studies available for rofecoxib and Angiogenesis, Pathologic
| Article | Year |
|---|---|
[Effect of polyunsaturated fatty acids ω-3 and ω-6 on angiogenesis formation in human gastric cancer].
Topics: Alprostadil; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Cell Count; Cell Line, Tumor; Ce | 2017 |
The role of COX-2 in angiogenesis and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Chemotaxis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C | 2003 |
[Effects of rofecoxib on angiogenesis of pancreatic cancer xenograft in nude mice].
Topics: Animals; Cyclooxygenase Inhibitors; Humans; Lactones; Male; Matrix Metalloproteinase 2; Matrix Metal | 2004 |
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.
Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother | 2005 |
Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Cell Line, | 2005 |
A new therapeutic approach in patients with advanced sarcoma.
Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cycl | 2005 |
Antiangiogenic activity of the selective cyclooxygenase 2 inhibitor rofecoxib in human colorectal cancer liver metastases.
Topics: Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Endostatins; Humans; Lactones; Liver Neoplasms; N | 2006 |
Targeting angiogenic processes by combination rofecoxib and ionizing radiation.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Apoptosis; Cell Division; Cells, Cultured; Cyclooxygenase 2 | 2001 |