Page last updated: 2024-11-04

rofecoxib and Adenoma, Basal Cell

rofecoxib has been researched along with Adenoma, Basal Cell in 7 studies

Research Excerpts

ExcerptRelevanceReference
" We conducted a randomized, placebo-controlled, double-blind trial to assess whether use of the selective COX-2 inhibitor rofecoxib would reduce the risk of colorectal adenomas."9.12A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. ( Baron, JA; Bolognese, JA; Bresalier, RS; Horgan, K; Lanas, A; Loftus, S; Morton, DG; Oxenius, B; Quan, H; Riddell, R; Sandler, RS, 2006)
" We report on cardiovascular adverse events in patients receiving rofecoxib to reduce rates of recurrence of colorectal cancer."9.12Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. ( Dunn, JA; Duvvuri, R; Iveson, C; Julier, P; Kerr, DJ; Langman, MJ; McConkey, CC; Midgley, RS; Smith, JL; Stanley, A; Stokes, JC, 2007)
" We conducted a randomized, placebo-controlled, double-blind trial to assess whether use of the selective COX-2 inhibitor rofecoxib would reduce the risk of colorectal adenomas."5.12A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. ( Baron, JA; Bolognese, JA; Bresalier, RS; Horgan, K; Lanas, A; Loftus, S; Morton, DG; Oxenius, B; Quan, H; Riddell, R; Sandler, RS, 2006)
" We report on cardiovascular adverse events in patients receiving rofecoxib to reduce rates of recurrence of colorectal cancer."5.12Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. ( Dunn, JA; Duvvuri, R; Iveson, C; Julier, P; Kerr, DJ; Langman, MJ; McConkey, CC; Midgley, RS; Smith, JL; Stanley, A; Stokes, JC, 2007)
"Most colorectal cancers are believed to develop from colorectal adenomas."1.32The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence. ( Bardou, M; Barkun, AN; Rahme, E; Toubouti, Y, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rahme, E1
Barkun, AN1
Toubouti, Y1
Bardou, M1
Senior, K1
Noguera Aguilar, JF1
Amengual Antich, I1
Morón Canis, JM1
Plaza Martínez, A1
Martínez Córcoles, JA1
Tortajada Collado, C1
Pujol Tugores, JJ1
Lee, YH1
Ji, JD1
Song, GG1
Baron, JA1
Sandler, RS1
Bresalier, RS1
Quan, H1
Riddell, R1
Lanas, A1
Bolognese, JA1
Oxenius, B1
Horgan, K1
Loftus, S1
Morton, DG1
Lynch, PM1
Kerr, DJ1
Dunn, JA1
Langman, MJ1
Smith, JL1
Midgley, RS1
Stanley, A1
Stokes, JC1
Julier, P1
Iveson, C1
Duvvuri, R1
McConkey, CC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Worldwide, Multicenter, Double-Blind, Randomized, Parallel, Placebo-Controlled Study to Evaluate the Lipid-Altering Efficacy, Safety and Tolerability of MK0524A in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia[NCT00269204]Phase 31,620 participants (Actual)Interventional2005-12-31Completed
A Multicenter, Randomized, Parallel-Group, Placebo-Controlled, Double-Blind Study With In-House Blinding to Determine the Effect of 156 Weeks of Treatment With MK0966 on the Recurrence of Neoplastic Polyps of the Large Bowel in Patients With a History of [NCT00282386]Phase 32,586 participants (Actual)Interventional1999-12-23Completed
Phase III, Randomized, Double Blind, Placebo Controlled Study of Rofecoxib in Colorectal Cancer Patients Following Adjuvant Chemotherapy[NCT00031863]Phase 30 participants Interventional2001-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for rofecoxib and Adenoma, Basal Cell

ArticleYear
Adjusted indirect comparison of celecoxib versus rofecoxib on cardiovascular risk.
    Rheumatology international, 2007, Volume: 27, Issue:5

    Topics: Adenoma; Adenomatous Polyps; Angina, Unstable; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactone

2007
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Chemoprevention; Colonoscopy; Colorectal Neoplasms; Cycloox

2006
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Chemoprevention; Colonoscopy; Colorectal Neoplasms; Cycloox

2006
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Chemoprevention; Colonoscopy; Colorectal Neoplasms; Cycloox

2006
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Chemoprevention; Colonoscopy; Colorectal Neoplasms; Cycloox

2006
Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer.
    The New England journal of medicine, 2007, Jul-26, Volume: 357, Issue:4

    Topics: Adenoma; Aged; Cardiovascular Diseases; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cyclooxygenase

2007

Other Studies

4 other studies available for rofecoxib and Adenoma, Basal Cell

ArticleYear
The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence.
    Gastroenterology, 2003, Volume: 125, Issue:2

    Topics: Adenoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cel

2003
COX-2 inhibitors: cancer prevention or cardiovascular risk?
    The Lancet. Oncology, 2005, Volume: 6, Issue:2

    Topics: Adenoma; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy

2005
Effect of rofecoxib on colon chemical carcinogenesis at colonic anastomotic area in the rat.
    Revista espanola de enfermedades digestivas, 2005, Volume: 97, Issue:6

    Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Car

2005
Is the demonstration of adenoma reduction with rofecoxib a pyrrhic victory?
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adenoma; Celecoxib; Chemoprevention; Colonoscopy; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors;

2006