Page last updated: 2024-11-04

rofecoxib and Abdominal Pain

rofecoxib has been researched along with Abdominal Pain in 5 studies

Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.

Research Excerpts

ExcerptRelevanceReference
"1), the rofecoxib group vs the Arthrotec group respectively reported diarrhea 6."9.09Tolerability profiles of rofecoxib (Vioxx) and Arthrotec. A comparison of six weeks treatment in patients with osteoarthritis. ( Acevedo, E; Beaulieu, AD; Caeiro, F; Casas, N; Castañeda, O; Garza-Elizondo, M; Gutierrez-Ureña, S; Hinojosa, W; Irazoque, F; Laurenzi, M; Pons-Estel, B; Rodgers, DB; Ugaz, M; Vandormael, K, 2001)
" To test whether COX-2 inhibition with rofecoxib would have greater GI tolerability than nonselective COX-1 and COX-2 inhibition, we compared the incidences of (1) treatment discontinuations for GI adverse events (AEs) and (2) prespecified dyspeptic-type GI AEs among patients with osteoarthritis treated with rofecoxib vs NSAIDs."8.80Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis. ( Bolognese, JA; Harper, SE; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL, 2000)
"1), the rofecoxib group vs the Arthrotec group respectively reported diarrhea 6."5.09Tolerability profiles of rofecoxib (Vioxx) and Arthrotec. A comparison of six weeks treatment in patients with osteoarthritis. ( Acevedo, E; Beaulieu, AD; Caeiro, F; Casas, N; Castañeda, O; Garza-Elizondo, M; Gutierrez-Ureña, S; Hinojosa, W; Irazoque, F; Laurenzi, M; Pons-Estel, B; Rodgers, DB; Ugaz, M; Vandormael, K, 2001)
" To test whether COX-2 inhibition with rofecoxib would have greater GI tolerability than nonselective COX-1 and COX-2 inhibition, we compared the incidences of (1) treatment discontinuations for GI adverse events (AEs) and (2) prespecified dyspeptic-type GI AEs among patients with osteoarthritis treated with rofecoxib vs NSAIDs."4.80Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis. ( Bolognese, JA; Harper, SE; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL, 2000)
" This effect was prevented by rofecoxib treatment indicating the sensitivity of the model for pelvic pain related to peritonitis."3.80Use of dynamic weight bearing as a novel end-point for the assessment of abdominal pain in the LPS-induced peritonitis model in the rat. ( Gruen, M; Laux-Biehlmann, A; Nagel, J; Zollner, TM, 2014)
"Rofecoxib is a selective cyclooxygenase-2 inhibitor that has been approved for the treatment of osteoarthritis and management of acute pain."1.33Ischemic colitis associated with rofecoxib. ( Feltri, M; Meucci, G; Minoli, G; Radaelli, F; Spinzi, G; Terruzzi, V, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gruen, M1
Laux-Biehlmann, A1
Zollner, TM1
Nagel, J1
Charachon, A1
Petit, T1
Lamarque, D1
Soulé, JC1
Radaelli, F1
Feltri, M1
Meucci, G1
Spinzi, G1
Terruzzi, V1
Minoli, G1
Watson, DJ1
Harper, SE1
Zhao, PL1
Quan, H1
Bolognese, JA1
Simon, TJ1
Acevedo, E1
Castañeda, O1
Ugaz, M1
Beaulieu, AD1
Pons-Estel, B1
Caeiro, F1
Casas, N1
Garza-Elizondo, M1
Irazoque, F1
Hinojosa, W1
Gutierrez-Ureña, S1
Vandormael, K1
Rodgers, DB1
Laurenzi, M1

Reviews

1 review available for rofecoxib and Abdominal Pain

ArticleYear
Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis.
    Archives of internal medicine, 2000, Oct-23, Volume: 160, Issue:19

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Clinical Tr

2000

Trials

1 trial available for rofecoxib and Abdominal Pain

ArticleYear
Tolerability profiles of rofecoxib (Vioxx) and Arthrotec. A comparison of six weeks treatment in patients with osteoarthritis.
    Scandinavian journal of rheumatology, 2001, Volume: 30, Issue:1

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygen

2001

Other Studies

3 other studies available for rofecoxib and Abdominal Pain

ArticleYear
Use of dynamic weight bearing as a novel end-point for the assessment of abdominal pain in the LPS-induced peritonitis model in the rat.
    Journal of neuroscience methods, 2014, Jul-30, Volume: 232

    Topics: Abdominal Pain; Analysis of Variance; Animals; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Mo

2014
[Acute ulcerative colitis in a patient treated with rofecoxib who took aspirin as self-medication].
    Gastroenterologie clinique et biologique, 2003, Volume: 27, Issue:5

    Topics: Abdominal Pain; Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Biopsy;

2003
Ischemic colitis associated with rofecoxib.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:5

    Topics: Abdominal Pain; Colitis, Ischemic; Colon; Cyclooxygenase Inhibitors; Female; Gastrointestinal Hemorr

2005