rocuronium and Syndrome

Rapid-onset obesity, hypoventilation, hypothalamic dysfunction, and autonomic dysfunction is an increasingly common diagnosis in patients who are being seen at tertiary care children's hospitals. We present two cases of anesthetics from the authors' own experience in addition to a comprehensive review of the disorder and anesthetic implications.

Topics: Adjuvants, Anesthesia; Analgesics; Androstanols; Anesthesia, General; Anesthetics, Inhalation; Atropine; Autonomic Dysreflexia; Child; Child, Preschool; Colonoscopy; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypothalamic Diseases; Hypoventilation; Intubation; Ketamine; Methyl Ethers; Neuromuscular Depolarizing Agents; Obesity; Rocuronium; Sevoflurane; Syndrome; Tracheostomy

Topics: Abnormalities, Multiple; Androstanols; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Facies; Female; Humans; Infant, Newborn; Intubation, Gastrointestinal; Intubation, Intratracheal; Isoflurane; Neuromuscular Nondepolarizing Agents; Piperidines; Prenatal Diagnosis; Propofol; Remifentanil; Rocuronium; Stomach; Syndrome

Topics: Abnormalities, Multiple; Alfentanil; Androstanols; Anesthesia; Anesthesia, Epidural; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Child, Preschool; Desflurane; Female; Femur; Fractures, Bone; Hip Dislocation, Congenital; Humans; Intellectual Disability; Isoflurane; Monitoring, Intraoperative; Muscular Diseases; Neuromuscular Nondepolarizing Agents; Orthopedic Procedures; Propofol; Rocuronium; Sufentanil; Syndrome

Gordon's syndrome is a rare condition characterized by hypertension and hyperkalemia despite normal renal glomerular function. We report the administration of an anaesthetic to one such patient for an urgent surgical procedure. The patient's serum potassium was only marginally raised at the outset of the procedure. During surgery the serum potassium rose significantly, but responded to conventional management. Hyperkalaemia is a specific electrolyte disturbance that has numerous implications for the administration of an anaesthetic. Most importantly, there is a danger that further acute elevations may occur, caused by the surgery, the anaesthetic, or the condition itself

Topics: Accidents, Traffic; Androstanols; Anesthesia; Emergencies; Glomerular Filtration Rate; Humans; Hyperkalemia; Hypertension; Male; Middle Aged; Neuromuscular Nondepolarizing Agents; Potassium; Rocuronium; Syndrome

Robinow (fetal face) syndrome is a rare inherited multisystem disorder featuring mesomelic or acromesomelic limb shortening, facial and spinal deformities, hypoplastic genitalia, kidney disease and congenital heart defects. We report the anaesthetic management of a patient with Robinow syndrome presenting for elective surgery and review specific issues of interest in the perioperative workup.

Topics: Abnormalities, Multiple; Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child, Preschool; Dwarfism; Face; Female; Fentanyl; Heart Defects, Congenital; Humans; Intubation, Intratracheal; Kidney Function Tests; Limb Deformities, Congenital; Liver Function Tests; Methyl Ethers; Neuromuscular Nondepolarizing Agents; Propofol; Rhinoplasty; Rocuronium; Sevoflurane; Spine; Syndrome