ro13-9904 and Uveitis--Intermediate

To describe a case of uveitis that is associated with Borrelia hermsii relapsing fever.. Interventional case report.. A 12-year-old boy with two weeks of relapsing fevers 10 days after camping in remote eastern Oregon was examined. Borrelia hermsii immunoglobulin M and G levels were markedly elevated. Intravenous ceftriaxone, followed by four weeks of oral cephuroxime was administered, but the patient developed unilateral floaters and blurred vision in association with anterior and intermediate uveitis.. Doxycycline was administered for presumed residual infection. Four weeks later, the visual acuity had improved. The anterior chamber was quiet, and topical corticosteroid was tapered successfully.. Although rare, Borrelia hermsii should be included in the list of spirochetal diseases that are associated with uveitis.

Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Borrelia; Ceftriaxone; Cefuroxime; Child; Doxycycline; Drug Therapy, Combination; Eye Infections, Bacterial; Humans; Immunoglobulin G; Immunoglobulin M; Male; Relapsing Fever; Uveitis, Anterior; Uveitis, Intermediate

A case of chronic intermediate uveitis and associated classic snowbanking (pars planitis) with severe cystoid macular oedema probably due to Lyme borreliosis is reported. Despite a disease duration of 10 years the patient's ocular symptoms and visual acuity responded promptly to intravenous ceftriaxone treatment. This case demonstrates that periodic reevaluation of patients with intermediate uveitis is necessary to obtain a specific diagnosis which may include Lyme borreliosis.

Topics: Adult; Ceftriaxone; Humans; Lyme Disease; Male; Uveitis, Intermediate; Vision Disorders; Visual Acuity