ro13-9904 and Transposition-of-Great-Vessels

We report multiple and diffuse supratentorial and infratentorial brain abscesses in a ten months old girl with D- transposition of great arteries. The child was managed medically with intravenous antibiotics for 4 weeks. Her fever settled, however, weakness of right half of the body persisted despite remarkable improvement. Multiple abscesses (about 40 in number), in a child less than 2 years age, associated neutrophilia with toxic granulations and successful therapy with antibiotics alone makes this an unusual case.

Topics: Brain Abscess; Ceftriaxone; Female; Humans; Infant; Metronidazole; Tomography, X-Ray Computed; Transposition of Great Vessels

A case of native valve endocarditis caused by Enterococcus durans in a patient with transposition of the great vessels is reported. The patient was treated initially with gentamicin and ceftriaxone; after isolation of enterococci, ceftriaxone was switched to ampicillin. The only virulence factors established in the strain were haemolytic activity and biofilm formation.

Topics: Adult; Ampicillin; Biofilms; Ceftriaxone; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus; Gentamicins; Gram-Positive Bacterial Infections; Hemolysis; Humans; Male; Microbial Sensitivity Tests; Transposition of Great Vessels; Virulence