ro13-9904 and Spinal-Cord-Diseases

Early neurological Lyme disease (neuroborreliosis) typically presents with well-recognised neurological syndromes. Spinal myoclonus is however a rare manifestation of neuroborreliosis. We present the case of a man who developed spinal myoclonus 3 weeks after returning from the Czech Republic where he developed erythema migrans on his arm following multiple tick exposures. Spinal fluid analysis showed a pleocytosis and MRI showed enhancement at C5-C6. His serology was positive for IgM antibodies to

Topics: Administration, Intravenous; Aged; Anti-Bacterial Agents; Ceftriaxone; Diagnosis, Differential; Humans; Lyme Disease; Lyme Neuroborreliosis; Magnetic Resonance Imaging; Male; Myoclonus; Spinal Cord Diseases; Spinal Puncture; Tick Bites; Treatment Outcome

Spinal intramedullary abscesses are rare and potentially devastating lesions. Infection is mostly caused by staphylococci. Anaerobes are rare and often polymicrobial. We report an unusual case of spinal cord intramedullary abscess in a 7-month-old infant with monomicrobial infection due to Finegoldia magna. She was found to have a missed congenital thoracic dermal sinus. The patient was treated with metronidazole and ceftriaxone for 8 weeks, and improvement of the infection was documented. Clinical awareness of patients at risk is crucial for early diagnosis and intervention. As detection methods continue to improve for Finegoldia magna, it is important to increase awareness of the pathogenic role of this organism.

Topics: Abscess; Anti-Bacterial Agents; Ceftriaxone; Female; Firmicutes; Gram-Positive Bacterial Infections; Humans; Infant; Metronidazole; Spina Bifida Occulta; Spinal Cord Diseases; Treatment Outcome; Yemen

Haemophilus paraphrophilus was recovered in pure culture from purulent material collected at surgery from a patient presenting with a spinal epidural abscess and a severe neurological deficit. This is the first report of such an occurrence.

Topics: Abscess; Aged; Ceftriaxone; Combined Modality Therapy; Epidural Space; Haemophilus; Haemophilus Infections; Humans; Male; Spinal Cord Diseases