ro13-9904 has been researched along with Salmonella-Food-Poisoning* in 7 studies
1 review(s) available for ro13-9904 and Salmonella-Food-Poisoning
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Ceftiofur-resistant
Codex published the 'Guidelines for Risk Analysis of Foodborne Antimicrobial Resistance' to standardise the approach for evaluating risk posed by foodborne antimicrobial-resistant bacteria. One of the first steps in the guidelines is to compile a risk profile, which provides the current state of knowledge regarding a food safety issue, describes risk management options and recommends next steps. In Canada, ceftiofur/ceftriaxone-resistant Salmonella enterica subsp. enterica serovar Heidelberg from poultry was identified as an antimicrobial resistance (AMR) food safety issue. The first objective of this article was to contextualise this food safety issue, using the risk profile format of the Codex Guidelines. A second objective was to evaluate the applicability of the Codex Guidelines. This risk profile indicated that ceftiofur/ceftriaxone-resistant S. Heidelberg (CSH) was commonly isolated from poultry and was associated with severe disease in humans. Ceftiofur use in poultry hatcheries temporally mirrored the prevalence of CSH from poultry meat at retail and from people with salmonellosis. The evidence was sufficient to indicate the need for risk management options, such as restricting the use of ceftiofur in poultry. The Codex Guidelines provided a useful approach to summarise data for decision-makers to evaluate an AMR food safety issue. Topics: Animals; Anti-Bacterial Agents; Canada; Ceftriaxone; Cephalosporins; Drug Resistance, Bacterial; Food Microbiology; Humans; Microbial Sensitivity Tests; Poultry; Practice Guidelines as Topic; Risk Assessment; Risk Management; Salmonella enterica; Salmonella Food Poisoning | 2019 |
6 other study(ies) available for ro13-9904 and Salmonella-Food-Poisoning
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Ceftriaxone-Resistant Nontyphoidal Salmonella from Humans, Retail Meats, and Food Animals in the United States, 1996-2013.
Ceftriaxone resistance in Salmonella is a serious public health threat. Ceftriaxone is commonly used to treat severe Salmonella infections, especially in children. Identifying the sources and drivers of ceftriaxone resistance among nontyphoidal Salmonella is crucial.. The National Antimicrobial Resistance Monitoring System (NARMS) tracks antimicrobial resistance in foodborne and other enteric bacteria from humans, retail meats, and food animals. We examined NARMS data reported during 1996-2013 to characterize ceftriaxone-resistant Salmonella infections in humans. We used Spearman rank correlation to examine the relationships between the annual percentage of ceftriaxone resistance among Salmonella isolates from humans with isolates from retail meats and food animals.. A total of 978 (2.9%) of 34,100 nontyphoidal Salmonella isolates from humans were resistant to ceftriaxone. Many (40%) ceftriaxone-resistant isolates were from children younger than 18 years. Most ceftriaxone-resistant isolates were one of three serotypes: Newport (40%), Typhimurium (26%), or Heidelberg (12%). All were resistant to other antimicrobials, and resistance varied by serotype. We found statistically significant correlations in ceftriaxone resistance between human and ground beef Newport isolates (r = 0.83), between human and cattle Typhimurium isolates (r = 0.57), between human and chicken Heidelberg isolates (r = 0.65), and between human and turkey Heidelberg isolates (r = 0.67).. Ceftriaxone resistance among Salmonella Newport, Typhimurium, and Heidelberg isolates from humans strongly correlates with ceftriaxone resistance in isolates from ground beef, cattle, and poultry, respectively. These findings support other lines of evidence that food animals are important reservoirs of ceftriaxone-resistant Salmonella that cause human illness in the United States. Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Ceftriaxone; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Female; Food Contamination; Food Microbiology; Humans; Infant; Male; Microbial Sensitivity Tests; Middle Aged; Poultry; Red Meat; Salmonella; Salmonella Food Poisoning; United States; Young Adult | 2017 |
Clinical outcomes of nalidixic acid, ceftriaxone, and multidrug-resistant nontyphoidal salmonella infections compared with pansusceptible infections in FoodNet sites, 2006-2008.
Nontyphoidal Salmonella causes an estimated 1.2 million infections, 23,000 hospitalizations, and 450 deaths annually in the United States. Most illnesses are self-limited; however, treatment with antimicrobial agents can be life-saving for invasive infections.. The Foodborne Diseases Active Surveillance Network and the National Antimicrobial Resistance Monitoring System collaborated on a prospective cohort study of patients with nontyphoidal Salmonella bloodstream and gastrointestinal infections to determine differences in the clinical outcomes of resistant compared with pansusceptible infections. Interviews were conducted within 85 days of specimen collection date.. Of 875 nontyphoidal Salmonella isolates, 705 (81%) were pansusceptible, 165 (19%) were resistant to at least 1 agent, and 5 (0.6%) had only intermediate resistance. The most common pattern, found in 51 (31%) of resistant isolates, was resistance to at least ampicillin, chloramphenicol, streptomycin, sulfisoxazole, and tetracycline (ACSSuT); 88% of isolates with this pattern were serotype Typhimurium or Newport. Fourteen (52%) of the 27 ceftriaxone-resistant isolates were also ACSSuT resistant. Adjusted for age and serotype, bloodstream infection was significantly more common among patients infected with strains resistant to only two, only three, or only five antimicrobial classes, to ACSSuT with or without other agents, to ACSSuT only, or to nalidixic acid with or without other agents than among patients with pansusceptible isolates. Adjusted for age, serotype, and bloodstream infection, hospitalization was significantly more common among patients infected with strains resistant to only three agents or to ceftriaxone (all ceftriaxone-resistant isolates were resistant to other agents) than among patients with pansusceptible isolates.. This study extends evidence that patients with antimicrobial-resistant nontyphoidal Salmonella infections have more severe outcomes. Prevention efforts are needed to reduce unnecessary antimicrobial use in patient care settings and in food animals to help prevent the emergence of resistance and infections with resistant nontyphoidal Salmonella. Topics: Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Ceftriaxone; Child; Child, Preschool; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Female; Food Contamination; Food Microbiology; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nalidixic Acid; Prospective Studies; Salmonella; Salmonella Food Poisoning; Streptomycin; Sulfisoxazole; Tetracycline; Treatment Outcome; Young Adult | 2014 |
Characterization of Salmonella food isolates with concurrent resistance to ceftriaxone and ciprofloxacin.
Foodborne salmonellosis is an important public health problem worldwide. Most human Salmonella infections occur through the consumption of contaminated food of animal origin. The study reported the first isolation of two Salmonella enterica serovar Oranienburg strains from pork in China with concurrent resistance to ciprofloxacin and ceftriaxone. Both isolates also showed resistance to norfloxacin, trimethoprim-sulfamethoxazole, and chloramphenicol, and an elevated minimal inhibitory concentraton of azithromycin; one strain was also resistant to amikacin, gentamicin, tetracycline, and amoxicillin-clavulanic acid. Salmonella ceftriaxone resistance was due to the production of IncN plasmidborne CTX-M-14 ESBL, and their ciprofloxacin resistance was mediated by target mutations and efflux pump activity. This is the first time that ceftriaxone- and ciprofloxacin-resistant Salmonella was reported in meat products, which may be due to the uses of antibiotics in animal production. The study warrants the continuous surveillance of multidrug-resistant Salmonella in meat products and cautious use of antibiotics in food animals. Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftriaxone; China; Ciprofloxacin; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Food Contamination; Humans; Meat; Microbial Sensitivity Tests; Mutation; Plasmids; Salmonella; Salmonella Food Poisoning; Swine; Swine Diseases | 2013 |
Nontyphoidal Salmonella prosthetic valve endocarditis.
Topics: Aged; Anti-Bacterial Agents; Ceftriaxone; Combined Modality Therapy; Debridement; Device Removal; Echocardiography, Transesophageal; Endocarditis, Bacterial; Female; Humans; Prosthesis-Related Infections; Reoperation; Salmonella; Salmonella Food Poisoning; Salmonella Infections; Salmonella typhimurium; Spouses | 2012 |
Salmonella enteritidis induced myocarditis in a 16-year-old girl.
Myocarditis typically presents with non-specific clinical symptoms, and can easily be missed in the absence of a high index of clinical suspicion. Myocarditis caused by bacterial pathogens is rare in immunocompetent individuals, more commonly seen following viral infection. Although more classically associated with typhoid fever and gastroenteritis, Salmonella species are a rare cause of myocarditis. We report a case of Salmonella enteritidis-induced myocarditis after gastrointestinal infection in a 16 year-old girl, and discuss the diagnostic tools currently utilised to ascertain the diagnosis. Topics: Adolescent; Ceftriaxone; Diagnosis, Differential; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Gastroenteritis; Humans; Myocarditis; Pulmonary Edema; Salmonella enteritidis; Salmonella Food Poisoning; Salmonella Infections; Tachycardia | 2012 |
Salmonella typhimurium osteomyelitis of the femur in patient with Crohn's disease.
Osteomyelitis is an inflammation of the bone caused by infecting organisms. We present here the first case of osteomyelitis of the distal femur caused by Salmonella typhimurium in a patient with Crohn's disease. The infection was successfully treated with a combination of antibiotics and surgical treatment. Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Ceftriaxone; Combined Modality Therapy; Crohn Disease; Femur; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Middle Aged; Opportunistic Infections; Osteomyelitis; Postoperative Care; Postoperative Complications; Radionuclide Imaging; Salmonella Food Poisoning; Salmonella Infections; Salmonella typhimurium | 2010 |