ro13-9904 and Keratoconjunctivitis

To describe a case of primary meningococcal conjunctivitis mimicking epidemic keratoconjunctivitis.. Review of a case history and current literature.. A 28-year-old man presented with 5 days of a bilateral follicular conjunctivitis and subepithelial corneal infiltrates. Initial diagnosis of adenoviral conjunctivitis was made. Initial Gram stain of conjunctival exudates was negative. Cultures grew Neisseria meningitidis. Systemic antibiotics were instituted with adjunctive topical therapy. The conjunctivitis resolved with no evidence of systemic invasion.. The clinical picture of Neisseria meningitidis conjunctivitis can overlap with other infectious organisms including adenovirus. Early diagnosis and systemic antibiotic therapy are critical to prevent bacteremic spread of infection.

Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Keratoconjunctivitis; Male; Meningitis, Meningococcal; Neisseria meningitidis; Penicillins

Topics: Anti-Bacterial Agents; Cefmenoxime; Ceftriaxone; Corneal Perforation; Corneal Transplantation; Drug Therapy, Combination; Erythromycin; Gonorrhea; Humans; Keratoconjunctivitis; Male; Young Adult

Topics: Anti-Bacterial Agents; Ceftriaxone; Cellulitis; Female; Gonorrhea; Humans; Keratoconjunctivitis; Middle Aged; Neisseria gonorrhoeae; Tomography, X-Ray Computed

Infectious conjunctivitis is a very common presentation to medical professional and ophthalmologist all over the world. Although its typically self-limiting and treatable in almost all of the cases, but we need to be aware of the rare and potentially life threatening if the cause is not promptly identified and treated accordingly. In our case report, we highlighted the rare case of Neisseria meningitidis as a primary cause of keratoconjunctivitis. Neisseria meningitidis is a rare etiology of keratoconjunctivitis and its ocular presentations are quite similar with other bacterial or viral infection. The infection may potentially fatal if systemic invasion occurred, however with immediate and proper treatment the outcome is satisfactory. Early diagnosis and proper antibiotic treatment are critical to prevent systemic spread of the infection. Public health intervention is needed to prevent outbreak of the disease.

Topics: Anti-Bacterial Agents; Ceftriaxone; Child, Preschool; Humans; Keratoconjunctivitis; Male; Meningococcal Infections; Neisseria meningitidis

We present a 46-year-old man diagnosed initially with atypical adenoviral conjunctivitis and advanced marginal queratolysis with risk of perforation. The final diagnosis was gonococcal keratoconjunctivitis. The patient was successfully treated with amniotic membrane transplant, topic and systemic ceftriaxone (50 mg/ml and 1 grame/12 hours intravenous).. Gonorrhea must be suspected in cases of torpid evolution conjunctivitis.

Topics: Aged; Amnion; Anti-Bacterial Agents; Ceftriaxone; Gonorrhea; Humans; Keratoconjunctivitis; Male; Neisseria gonorrhoeae; Treatment Outcome; Visual Acuity

A 29-year-old man presented with a 5-day history of a red eye with a purulent discharge. Three years previously, he had undergone laser in situ keratomileusis elsewhere. A diagnosis of gonococcal keratoconjuntivitis was made clinically and confirmed with culture. The patient subsequently developed diffuse lamellar keratitis (DLK). The keratoconjunctivitis and DLK resolved with antibiotic therapy and topical steroids. The cause and effect relationship of these 2 uncommon events is of interest.

Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Ciprofloxacin; Corneal Stroma; Doxycycline; Drug Therapy, Combination; Eye Infections, Bacterial; Gonorrhea; Humans; Keratitis; Keratoconjunctivitis; Keratomileusis, Laser In Situ; Male; Neisseria gonorrhoeae; Surgical Flaps

Topics: Adult; Ceftriaxone; Cefuroxime; Cellulitis; Diagnosis, Differential; Drug Therapy, Combination; Eye Infections, Bacterial; Genital Diseases, Male; Gonorrhea; Humans; Keratoconjunctivitis; Male; Neisseria gonorrhoeae; Orbital Diseases