ro13-9904 has been researched along with Hypertrophy* in 2 studies
2 other study(ies) available for ro13-9904 and Hypertrophy
| Article | Year |
|---|---|
Mastoiditis complicated with Gradenigo syndrome and a hypertrophic pachymeningitis with consequent communicating hydrocephalus.
We present the clinical, radiological and pathological features of a case of a cranial hypertrophic pachymeningitis that developed in the course of mastoiditis and petrous apex inflammation and responded to immunosuppressive therapy only. Documented by the development of clinical findings, magnetic resonance imaging, cerebrospinal fluid changes, histopathology findings, by otosurgical intervention and finally by the insertion of a ventriculo-peritoneal shunt, the case illustrates a gradual development of pachymeningitis with consequent hydrocephalus and intracranial hypertension. We consider this disease development an example of immune-induced proliferative fibrotic changes in meninges. Topics: Abducens Nerve Diseases; Anti-Bacterial Agents; Ceftriaxone; Cerebrospinal Fluid; Chloramphenicol; Drug Therapy, Combination; Humans; Hydrocephalus; Hypertrophy; Immunoglobulin G; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Mastoiditis; Meninges; Meningitis; Methotrexate; Methylprednisolone; Middle Aged; Otitis Media; Petrous Bone; Syndrome; Trigeminal Nerve Diseases | 2007 |
[A case of hypertrophic pachymeningitis, resolved by antimicrobial therapy].
A 65-year-old woman with diabetes mellitus and chronic otitis media developed headache, fever, and hoarseness, all of which did not responded to the oral antibiotics. As stiff neck and lower cranial nerve palsies appeared, bacterial meningitis was suspected. Neurological examination revealed the right hearing disturbance, right recurrent laryngeal nerve palsy, left sternocleidomastoid muscle atrophy and bilateral tongue atrophy. The CSF examination revealed mild pleocytosis and elevated protein, but no bacterial organism was cultured from the CSF. CT scans showed bilateral mastoiditis, and the right mastoid process and a posterior part of the petrous bone were eroded, indicating the exposed bony structures to the posterior fossa. MRI scans demonstrated the thickening of the dura mater of the posterior fossa and the right cerebellar tentorium. This is a rare example of bacterial pachymeningitis of the posterior fossa, the clinical symptoms and MRI findings of which resolved solely by antimicrobial agents without corticosteroid. Topics: Aged; Ceftriaxone; Female; Humans; Hypertrophy; Mastoiditis; Meningitis; Otitis Media | 2004 |