ro13-9904 and Biliary-Tract-Neoplasms

ro13-9904 has been researched along with Biliary-Tract-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for ro13-9904 and Biliary-Tract-Neoplasms

Article	Year
[Ceftriaxone in malignant occlusive jaundice. Studies of serum and bile concentration in disordered bile excretion]. Fortschritte der Medizin, 1993, Nov-20, Volume: 111, Issue:32 In 12 patients with inoperable malignant obstructive jaundice, percutaneous transhepatic biliary drainage was performed to decompensate the bile ducts. For a period of 7 days, the patients received a single daily i.v. dose of 1 g CFTX, and the serum and bile concentrations were measured at defined intervals.. The dose sufficed to kill about 85% of the expected organisms. Although an accumulation of the substance as documented under conditions of normal bile flow was not demonstrable under cholestatic conditions, effective levels were nevertheless found in the bile and showed a tendency to increase with increasing bile flow. Topics: Aged; Aged, 80 and over; Bile; Biliary Tract Neoplasms; Bilirubin; Ceftriaxone; Cholangitis; Cholestasis, Extrahepatic; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Middle Aged	1993

Article

Year

[Ceftriaxone in malignant occlusive jaundice. Studies of serum and bile concentration in disordered bile excretion].

Fortschritte der Medizin, 1993, Nov-20, Volume: 111, Issue:32

In 12 patients with inoperable malignant obstructive jaundice, percutaneous transhepatic biliary drainage was performed to decompensate the bile ducts. For a period of 7 days, the patients received a single daily i.v. dose of 1 g CFTX, and the serum and bile concentrations were measured at defined intervals.. The dose sufficed to kill about 85% of the expected organisms. Although an accumulation of the substance as documented under conditions of normal bile flow was not demonstrable under cholestatic conditions, effective levels were nevertheless found in the bile and showed a tendency to increase with increasing bile flow.

Topics: Aged; Aged, 80 and over; Bile; Biliary Tract Neoplasms; Bilirubin; Ceftriaxone; Cholangitis; Cholestasis, Extrahepatic; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Middle Aged

1993