ro13-9904 and Bartonellaceae-Infections

We present the clinical case of a man of 68 years who was admitted for dizziness and sensation of loss of conscience. The clinical examination revealed a body temperature of 37.5 degrees C and a murmur of mitral regurgitation. The echocardiogram showed a severe mitral regurgitation and left cavitie's dilatation; transesophageal echocardiogram showed a vegetation in the anterior leaflet of the mitral valve. In blood cultures grew a Gram-negative bacteria identified as Bartonella spp. A PCR demonstrated that it was a Bartonella quintana. The patient was treated with gentamicin, doxiciclin and ceftriaxone with satisfactory evolution. The remaining mitral insufficiency awaits surgical treatment.

Topics: Aged; Anti-Bacterial Agents; Bartonella quintana; Bartonellaceae Infections; Ceftriaxone; Endocarditis, Bacterial; Gentamicins; Humans; Male; Mitral Valve Insufficiency; Polymerase Chain Reaction