Page last updated: 2024-09-03

ro 8-0576 and Idiopathic Parkinson Disease

ro 8-0576 has been researched along with Idiopathic Parkinson Disease in 121 studies

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-199051 (42.15)18.7374
1990's25 (20.66)18.2507
2000's10 (8.26)29.6817
2010's32 (26.45)24.3611
2020's3 (2.48)2.80

Authors

AuthorsStudies
Cools, R; den Ouden, HEM; Dirkx, MF; Helmich, RC; Toni, I; van Nuland, AJ; Zach, H1
Babu, S; Chang, FC; Dal, S; Fletcher, N; Fung, VSC; Mahant, N; Martin, AJ; Morales-Briceno, H; Nankervis, J; Ong, TL; Robbie, M; Williams, LJ1
Jiang, DQ; Jiang, LL; Li, MX; Qiao, JY; Wang, Y; Zang, QM1
Bugdol, M; Czernek, M; Derejczyk, J; Kapko, W; Kawa, J; Marcisz, C; Seiffert, P; Stępień-Wyrobiec, O; Szymszal, J; Torbus, A1
Chang, MC; Lee, HD1
Bloem, BR; Dirkx, MF; Hallett, M; Helmich, RC; Zach, H1
Arnulfo, G; Canessa, A; Isaias, IU; Marotta, G; Olivieri, C; Palmisano, C; Pezzoli, G; Pozzi, NG; Turco, F; Volkmann, J1
Ali, M; Chandel, TI; Jahan, I; Khan, RH; Masroor, A; Nayeem, SM; Siddique, IA; Uversky, VN; Zaidi, N; Zaman, M1
Brandt, G; Canessa, A; Frigo, CA; Isaias, IU; Leporini, A; Maltese, V; Palmisano, C; Pezzoli, G; Pozzi, NG; Volkmann, J1
Alessandroni, J; Bonassi, S; Bravi, D; Casali, M; Fossati, C; Grassini, P; Ialongo, C; Onofrj, M; Radicati, FG; Stocchi, F; Torti, M; Vacca, L1
Arnet, I; Fischer, A; Gasser, UE; Timmermans, JP1
Ma, YZ; Shen, XM; Zhang, J1
Almeida, KJ; Campos Sousa, RN; de Oliveira Filho, MC; Guimarães Silva, JS; Lopes Nery, PC1
Bezard, E; De Deurwaerdere, P; Li, Q; Marti, M; Meissner, WG; Morari, M; Morgenstern, R; Porras, G; Sohr, R1
Hattori, N1
Che, JY; Gan, J; Liu, ZG; Song, L; Wang, WW; Xie, CL; Yuan, ML; Yuan, WE; Zhang, SF1
Falcão, A; Ferreira, JJ; Nunes, T; Pinto, R; Rocha, JF; Santos, A; Soares-da-Silva, P1
Alirezaei, M; Dezfoulian, O; Khoshdel, Z; Rashidipour, M; Taghadosi, V1
Baumann, CR; Epprecht, L; Goetze, O; Schreglmann, SR; Waldvogel, D; Woitalla, D1
Chen, C; Fan, Q; Huang, J; Pan, X; Wei, H1
Cao, ZH; Chen, HX; Ding, ZG; Song, JH; Zhang, GB; Zhou, PY1
De Wolf, C; Downey, P; Michel, A; Scheller, D; Schwarting, R; Van Damme, X1
Kuoppamäki, M; Leinonen, M; Poewe, W1
Chan, P; Feng, T; Hallett, M; Hou, Y; Wu, T; Zhang, J1
Calandra-Buonaura, G; Capellari, S; Contin, M; Cortelli, P; Doria, A; Guaraldi, P; Lopane, G; Martinelli, P1
Du, N; Guo, Z; Han, M; Huang, Y; Liu, J; Xu, S1
Almeida, L; Falcão, A; Ferreira, JJ; Nunes, T; Pinto, R; Rocha, JF; Santos, A; Soares-da-Silva, P1
Cao, LD; Guo, G; Wu, QY; Xu, S1
Ren, XM1
Hsu, CH; Wang, HB1
Huang, Y; Jiang, X; Tang, A; Wik, G; Zhuo, Y1
Adamiak, U; Bialecka, M; Gawronska-Szklarz, B; Kaldonska, M; Klodowska-Duda, G; Safranow, K; Wyska, E1
Eggert, K; Eichhorn, T; Oertel, WH; Ries, V; Selzer, R1
Kek, PC; Prakash, KM1
Inoue, T; Koyama, M; Ogata, A; Tani, Y1
Dick, OE; Nozdrachev, AD; Romanov, SP1
Li, M; Li, SD; Liu, Y; Yang, MH1
Li, M; Liu, Y; Yang, MH1
Ludin, HP2
Chen, XH; Kui, Y; Li, Y1
Lian, XF; Luo, XD1
Iadgarov, IS; Kandel', EI1
Csanda, E; Katona, G; Köves, A; Mogyorós, I; Takáts, A; Tárczy, M1
Csanda, E; Tárczy, M1
Liu, DK2
Caraceni, T; Cocchi, D; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A1
Agnoli, A; Baldassarre, M; D'Urso, R; De Giorgio, G; Falaschi, P; Rocco, A; Ruggieri, S1
Caraceni, T; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A; Parati, E1
Dessibourg, CA; Gachoud, JP1
Baas, H; Bergemann, N; Fischer, PA1
Bowes, SG; Charlett, A; Dobbs, RJ; Dobbs, SM; Nicholson, PW; O'Neill, CJ; Purkiss, A; Weller, C1
Eichhorn, TE; Kohnen, R; Oertel, WH; Poewe, W; Schrag, A; Selzer, R; Trenkwalder, C1
Dubuis, R; Limousin, P; Perret, JE; Pfefen, JP; Pollak, P; Tournier-Gervason, CL1
Andersen, A; Boas, J; Boisen, E; Borgmann, R; Buch, D; Dupont, E; Helgetveit, AC; Kjaer, MO; Kristensen, TN; Mikkelsen, B; Pakkenberg, H; Presthus, J; Stien, R; Worm-Petersen, J1
Shan, DE; Yeh, SI1
Cammarota, A; Leiguarda, R; Merello, M; Pikielny, R1
Barbato, L; Berardelli, A; Bonamartini, A; Manfredi, M; Patsalos, PN; Ruggieri, S; Stocchi, F1
Leiva, C1
Goetz, CG1
Bennett, KM; Bonfiglioli, C; Castiello, U; Peppard, RF1
Barbarino-Monnier, P; Denis, E; Lurel, S; Routiot, T1
Golubev, VL; Sadekov, RA; Vendrova, MI1
Brüne, M; Gerlach, G; Schröder, SG1
Gerlach, J1
Kleedorfer, B; Poewe, W1
Jenkins, JR; Pearce, JM1
Da Prada, M1
Graham, JS; Henderson, JM; Morris, JG; Yiannikas, C1
Cunningham, MA; Darby, DG; Donnan, GA1
Agnoli, A; Carta, A; Marsden, CD; Quinn, NP; Ruggieri, S; Steiger, MJ; Stocchi, F1
Aljanati, R; Buzó, R; Caamaño, JL; Chouza, C; De Medina, O; Fernandez, A; Plachín, V; Romero, S; Scaramelli, A1
Ceballos-Baumann, AO; Eckert, W; von Kummer, R; Weicker, H1
Blackburn, NA; Boddie, HG; Ellis, CJ; Kendal, BR; MacMahon, DG; Sachdev, D1
Lees, AJ2
Jansen, EN; Meerwaldtt, JD1
Covicković-Sternić, N; Kostić, VS1
Bruggi, P; Martignoni, E; Nappi, G; Pacchetti, C; Sibilla, L; Turla, M1
Berger, HJ; Horstink, MW; Pasman, JW; van't Hof, MA; Zijlmans, JC1
Dissing, IC; Gerdes, AM; Güttler, F; Lou, H; Lykkelund, C; Pakkenberg, H; Rasmussen, V1
Rinne, JO; Rinne, UK1
Dordain, G; Dostert, P; Strolin Benedetti, M; Vernay, D1
Ingvarsson, PE; Johnels, B; Steg, G; Thorselius, M; Valls, M1
d'Anglejan Chatillon, J1
Boomsma, F; Hovestadt, A; Man in 't Veld, AJ; Meerwaldt, JD; Schalekamp, MA1
Allain, H; Bentue-Ferrer, D; Defawe, G; Jacquemard, F; Milon, D; Moran, P1
Boomsma, F; Hovestadt, A; Man in't Veld, AJ; Meerwaldt, JD; Schalekamp, MA1
Koller, WC; Lang, AE; Marsden, CD; Quinn, NP1
Albani, C; Hacisalihzade, SS; Mansour, M1
Aljanati, R; Caamaño, JL; Chouza, C; de Medina, O; Romero, S; Scaramelli, A1
Cossutta, E; Ferrante, C; Pezzoli, G; Scarlato, G; Tesei, S; Zecchinelli, A1
Ketsche, R; Vogel, HP1
Stern, G1
Mondal, BK; Mondal, KN1
Birkmayer, GD; Birkmayer, W1
Csanda, E; Takáts, A; Tárczy, M1
Birkmayer, W1
Aymard, N; Holzer, J; Rondot, P; Ziegler, M2
Marion, MH; Marsden, CD; Quinn, NP1
Jenner, P; Malcolm, SL; Marion, MH; Marsden, CD; Quinn, NP; Stocchi, F1
D'Andrea, G; Durisotti, C; Ferro-Milone, F; Lion, P; Lorizio, A; Nordera, GP1
Baas, H; Fischer, PA1
Lees, AJ; Poewe, WH; Stern, GM1
Heersema, T; Jansen, EN; Meerwaldt, JD; Speelman, JD; van Manen, J1
Jansen, EN; Meerwaldt, JD1
Wermuth, L1
Rinne, UK1
Aljanati, R; Caamano, JL; Chouza, C; de Medina, O; Gonzales Panizza, V; Romero, S; Scarmelli, A1
Dupont, E; Hansen, E; Jensen, NO; Mikkelsen, B; Mikkelsen, BO1
Siegfried, J1
Jenner, P; Marion, MH; Marsden, CD; Quinn, NP; Stocchi, F1
Wilson, JA1
Albani, C; Asper, R; Baumgartner, G; Hacisalihzade, SS1
Zhou, XD1
Yu, HZ1
Steinhäusl, H1

Reviews

5 review(s) available for ro 8-0576 and Idiopathic Parkinson Disease

ArticleYear
Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson's disease: a systematic review and meta-analysis.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:9

    Topics: Antiparkinson Agents; Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Levodopa; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Treatment Outcome

2021
[Programs for continuing medical education: a session: 4. The pathogenesis and update for the treatments of Parkinson's disease].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Mar-10, Volume: 103, Issue:3

    Topics: Benserazide; Benzothiazoles; Catechols; Circadian Rhythm; Dementia; Dopamine Agonists; Drug Combinations; Drug Therapy, Combination; Drug Tolerance; Dyskinesias; Education, Medical, Continuing; Hallucinations; Humans; Levodopa; Nitriles; Parkinson Disease; Practice Guidelines as Topic; Pramipexole; Reference Standards; Referral and Consultation

2014
[Idiopathic Parkinson's disease: practical hints for the treatment].
    Praxis, 2005, Jul-27, Volume: 94, Issue:30-31

    Topics: Adult; Aged; Antidepressive Agents; Antiparkinson Agents; Antipsychotic Agents; Benserazide; Cholinesterase Inhibitors; Clozapine; Dementia; Depression; Diagnosis, Differential; Dopamine Agents; Dopamine Agonists; Drug Combinations; Humans; Levodopa; Parkinson Disease; Quality of Life; Sleep Wake Disorders; Time Factors

2005
[Parkinson's disease and pregnancy: case report and literature review].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2000, Volume: 29, Issue:5

    Topics: Adult; Antiparkinson Agents; Benserazide; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Parkinson Disease; Pregnancy; Pregnancy Complications; Pregnancy Outcome

2000
New approaches to the treatment of age-related brain disorders.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1991, Volume: 18, Issue:3 Suppl

    Topics: Aging; Alzheimer Disease; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Enzyme Inhibitors; Humans; Levodopa; Monoamine Oxidase Inhibitors; Nitrophenols; Parkinson Disease; Picolinic Acids; Tolcapone

1991

Trials

46 trial(s) available for ro 8-0576 and Idiopathic Parkinson Disease

ArticleYear
Clinical and pharmacokinetics equivalence of multiple doses of levodopa benserazide generic formulation vs the originator (Madopar).
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:11

    Topics: Adult; Aged; Benserazide; Cross-Over Studies; Dopamine Agents; Double-Blind Method; Drug Combinations; Drugs, Generic; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Treatment Outcome

2019
Evaluation on the efficacy and safety of Chinese herbal medication Xifeng Dingchan Pill in treating Parkinson's disease: study protocol of a multicenter, open-label, randomized active-controlled trial.
    Journal of integrative medicine, 2013, Volume: 11, Issue:4

    Topics: Benserazide; Data Interpretation, Statistical; Drug Combinations; Drugs, Chinese Herbal; Humans; Levodopa; Medicine, Chinese Traditional; Parkinson Disease; Phytotherapy; Piribedil; Quality of Life

2013
Effect of opicapone on levodopa pharmacokinetics, catechol-O-methyltransferase activity and motor fluctuations in patients with Parkinson's disease.
    European journal of neurology, 2015, Volume: 22, Issue:5

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Benserazide; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Double-Blind Method; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Oxadiazoles; Parkinson Disease; Treatment Outcome

2015
Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal.
    Journal of neurology, 2015, Volume: 262, Issue:8

    Topics: Adult; Aged; Appetite; Benserazide; Breath Tests; Caprylates; Dopamine Agents; Drug Combinations; Gastric Emptying; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prospective Studies

2015
Rhythmic auditory stimulation with visual stimuli on motor and balance function of patients with Parkinson's disease.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:11

    Topics: Acoustic Stimulation; Aged; Benserazide; Benzothiazoles; Catechols; Dose-Response Relationship, Drug; Drug Combinations; Female; Gait; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Periodicity; Piribedil; Postural Balance; Pramipexole; Walking

2015
Efficacy and safety of entacapone in levodopa/carbidopa versus levodopa/benserazide treated Parkinson's disease patients with wearing-off.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:12

    Topics: Antiparkinson Agents; Benserazide; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Data Interpretation, Statistical; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Retrospective Studies; Treatment Outcome

2015
Neural correlates underlying micrographia in Parkinson's disease.
    Brain : a journal of neurology, 2016, Volume: 139, Issue:Pt 1

    Topics: Aged; Attention; Basal Ganglia; Benserazide; Brain Mapping; Case-Control Studies; Cerebellum; Drug Combinations; Female; Gyrus Cinguli; Handwriting; Humans; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Motor Cortex; Neural Pathways; Parkinson Disease

2016
Effect of 3 Single-Dose Regimens of Opicapone on Levodopa Pharmacokinetics, Catechol-O-Methyltransferase Activity and Motor Response in Patients With Parkinson Disease.
    Clinical pharmacology in drug development, 2016, Volume: 5, Issue:3

    Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Humans; Levodopa; Male; Middle Aged; Oxadiazoles; Parkinson Disease

2016
Fifty cases of Parkinson's disease treated by acupuncture combined with madopar.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2008, Volume: 28, Issue:4

    Topics: Acupuncture Therapy; Aged; Benserazide; Combined Modality Therapy; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome

2008
Pharmacokinetic-pharmacodynamic modeling of levodopa in patients with advanced Parkinson disease.
    Clinical neuropharmacology, 2010, Volume: 33, Issue:3

    Topics: Age of Onset; Aged; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Drug Therapy, Combination; Dyskinesias; Enzyme Inhibitors; Female; Half-Life; Humans; Levodopa; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Nitrophenols; Parkinson Disease; Severity of Illness Index; Tolcapone; Tyrosine

2010
Replacing a dopamine agonist by the COMT-inhibitor tolcapone as an adjunct to L-dopa in the treatment of Parkinson's disease: a randomized, multicenter, open-label, parallel-group study.
    Clinical neuropharmacology, 2010, Volume: 33, Issue:3

    Topics: Aged; Ambulatory Care Facilities; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Dopamine Agonists; Drug Combinations; Drug Therapy, Combination; Dyskinesias; Enzyme Inhibitors; Feasibility Studies; Female; Humans; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Severity of Illness Index; Time Factors; Tolcapone; Treatment Outcome

2010
[Effects of bushenhuoxue granules on sleep quality in Parkinson's patients].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:9

    Topics: Aged; Aged, 80 and over; Benserazide; Double-Blind Method; Drug Combinations; Drugs, Chinese Herbal; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phytotherapy; Plants, Medicinal; Polysomnography; Severity of Illness Index; Sleep Wake Disorders; Treatment Outcome

2011
[Effects of "attenuation and synergia" for Bushenhuoxue Granules on Parkinson's patients].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antiparkinson Agents; Benserazide; Constipation; Double-Blind Method; Drug Combinations; Drugs, Chinese Herbal; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phytotherapy; Plants, Medicinal; Treatment Outcome; Urination Disorders

2012
[Clinical observation on abdominal acupuncture plus Madopa for treatment of Parkinson's disease].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2007, Volume: 27, Issue:8

    Topics: Abdomen; Acupuncture Therapy; Adult; Aged; Benserazide; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

2007
[Effect of TCM treatment according to syndrome differentiation in enhancing curative effect and reducing side-effect of madopa].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2007, Volume: 27, Issue:9

    Topics: Aged; Aged, 80 and over; Benserazide; Diagnosis, Differential; Dopamine Agents; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Female; Humans; Levodopa; Male; Medicine, Chinese Traditional; Middle Aged; Parkinson Disease; Phytotherapy; Prospective Studies; Syndrome; Treatment Outcome

2007
[Slow-release L-dopa vs. standard L-dopa in Parkinson patients in various stages of the disease. Studies of pharmacokinetics and motor effectiveness].
    Der Nervenarzt, 1994, Volume: 65, Issue:4

    Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Levodopa; Male; Metabolic Clearance Rate; Middle Aged; Neurologic Examination; Parkinson Disease

1994
Defining small differences in efficacy between anti-parkinsonian agents using gait analysis: a comparison of two controlled release formulations of levodopa/decarboxylase inhibitor.
    British journal of clinical pharmacology, 1993, Volume: 35, Issue:4

    Topics: Aged; Analysis of Variance; Antiparkinson Agents; Benserazide; Carbidopa; Carboxy-Lyases; Delayed-Action Preparations; Drug Combinations; Female; Gait; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

1993
Acute administration of levodopa-benserazide and tolcapone, a COMT inhibitor, Parkinson's disease.
    Clinical neuropharmacology, 1995, Volume: 18, Issue:3

    Topics: Aged; Antiparkinson Agents; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Enzyme Inhibitors; Female; Humans; Levodopa; Male; Motor Activity; Nitrophenols; Parkinson Disease; Placebos; Tolcapone

1995
Sustained-release Madopar HBS compared with standard Madopar in the long-term treatment of de novo parkinsonian patients.
    Acta neurologica Scandinavica, 1996, Volume: 93, Issue:1

    Topics: Aged; Antiparkinson Agents; Benserazide; Delayed-Action Preparations; Denmark; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Norway; Parkinson Disease

1996
An add-on study of selegiline to Madopar in the treatment of parkinsonian patients with dose-related fluctuations: comparison between Jumexal and Parkryl.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1996, Volume: 58, Issue:4

    Topics: Aged; Antiparkinson Agents; Benserazide; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Humans; Levodopa; Middle Aged; Monoamine Oxidase Inhibitors; Movement; Parkinson Disease; Selegiline; Single-Blind Method

1996
Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in Parkinson's disease patients: a double-blind single-dose study.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:2

    Topics: Administration, Oral; Antiparkinson Agents; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Double-Blind Method; Drug Combinations; Enzyme Inhibitors; Female; Humans; Injections, Subcutaneous; Levodopa; Male; Middle Aged; Parkinson Disease

1997
[Efficiency of new forms of madopar in Parkinson's disease].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2000, Volume: 100, Issue:12

    Topics: Antiparkinson Agents; Benserazide; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome

2000
Effect of CB 154 (2-bromo-alpha-ergocryptine) on paralysis agitans compared with Madopar in a double-blind, cross-over trial.
    Acta neurologica Scandinavica, 1976, Volume: 53, Issue:3

    Topics: Aged; Azides; Benserazide; Bromocriptine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Ergolines; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Psychoses, Substance-Induced

1976
Comparative efficacy of two oral sustained-release preparations of L-dopa in fluctuating Parkinson's disease. Preliminary findings in 20 patients.
    Journal of neural transmission. Parkinson's disease and dementia section, 1992, Volume: 4, Issue:2

    Topics: Benserazide; Carbidopa; Delayed-Action Preparations; Drug Combinations; Follow-Up Studies; Humans; Levodopa; Parkinson Disease

1992
A comparison of standard Madopar and controlled release Madopar in Parkinson's disease.
    Australian and New Zealand journal of medicine, 1991, Volume: 21, Issue:1

    Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

1991
Controlled-release levodopa/benserazide (Madopar HBS): clinical observations and levodopa and dopamine plasma concentrations in fluctuating parkinsonian patients.
    Journal of neurology, 1990, Volume: 237, Issue:1

    Topics: Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Dopamine; Drug Combinations; Female; Follow-Up Studies; Hospitalization; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease

1990
A comparison of the effects of controlled-release levodopa (Madopar CR) with conventional levodopa in late Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Benserazide; Carboxy-Lyases; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Motor Skills; Multicenter Studies as Topic; Neurologic Examination; Parkinson Disease

1990
Madopar HBS (hydrodynamically balanced system) in the treatment of Parkinson's disease.
    Advances in neurology, 1990, Volume: 53

    Topics: Aged; Antiparkinson Agents; Benserazide; Circadian Rhythm; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease

1990
Madopar HBS in nocturnal symptoms of Parkinson's disease.
    Advances in neurology, 1990, Volume: 53

    Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Circadian Rhythm; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Sleep Stages

1990
Open study of sustained-release formulation of levodopa and benserazide in parkinsonian patients.
    Neurologija, 1990, Volume: 39, Issue:2

    Topics: Adult; Benserazide; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

1990
Effectiveness of Madopar HBS plus Madopar standard in patients with fluctuating Parkinson's disease: two years of follow-up.
    European neurology, 1990, Volume: 30, Issue:6

    Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1990
Tetrahydrobiopterin and Parkinson's disease.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:6

    Topics: Adult; Antiparkinson Agents; Benserazide; Biopterins; Clinical Trials as Topic; Drug Combinations; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine

1989
A comparison of Madopar CR and standard Madopar in the treatment of nocturnal and early-morning disability in Parkinson's disease. The U.K. Madopar CR Study Group.
    Clinical neuropharmacology, 1989, Volume: 12, Issue:6

    Topics: Activities of Daily Living; Aged; Benserazide; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Randomized Controlled Trials as Topic

1989
A combined regimen of subcutaneous lisuride and oral Madopar HBS in Parkinson's disease.
    Journal of neural transmission. Supplementum, 1988, Volume: 27

    Topics: Administration, Oral; Benserazide; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Drug Tolerance; Ergolines; Humans; Hydrazines; Infusion Pumps; Levodopa; Lisuride; Parkinson Disease; Severity of Illness Index

1988
Madopar HBS in fluctuating parkinsonian patients: two-year treatment.
    Movement disorders : official journal of the Movement Disorder Society, 1988, Volume: 3, Issue:1

    Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease

1988
Clinical trial of Madopar HBS in parkinsonian patients with fluctuating drug response after long-term levodopa therapy.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors

1987
Open study of Madopar HBS, a new formulation of levodopa with benserazide, in 13 patients with Parkinson's disease and 'on-off' fluctuations.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Single-dose studies of a slow-release preparation of levodopa and benserazide (Madopar HBS) in Parkinson's disease.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Benserazide; Biological Availability; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Random Allocation

1987
Open clinical study of Madopar HBS.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Infant, Newborn; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Treatment of parkinsonian conditions with a controlled-release form of levodopa--preliminary study.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Preliminary experience with Madopar HBS: clinical observations and plasma levodopa concentrations.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Clinical and pharmacokinetic observations with Madopar HBS in hospitalized patients with Parkinson's disease and motor fluctuations.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Hospitalization; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Open multicenter trial with Madopar HBS in parkinsonian patients. Preliminary assessment after short-term treatment.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors

1987
[Controlled release levodopa-benserazide and changes in efficacy during treatment of Parkinson's disease].
    Revue neurologique, 1987, Volume: 143, Issue:11

    Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors

1987
Single-dose study of slow release preparation of levodopa and benserazide (Madopar HBS) in Parkinson's disease.
    Advances in neurology, 1987, Volume: 45

    Topics: Administration, Oral; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Disability Evaluation; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Random Allocation

1987
[Experiences in the treatment of Parkinson's disease with a combination drug: L-dopa plus decarboxylase inhibitor (Ro 8-0576)].
    Wiener medizinische Wochenschrift (1946), 1973, Jun-30, Volume: 123, Issue:26

    Topics: Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Combinations; Evaluation Studies as Topic; Gastrointestinal Diseases; Gymnastics; Humans; Hydrazines; Levodopa; Parkinson Disease; Speech Therapy

1973

Other Studies

70 other study(ies) available for ro 8-0576 and Idiopathic Parkinson Disease

ArticleYear
Effects of dopamine on reinforcement learning in Parkinson's disease depend on motor phenotype.
    Brain : a journal of neurology, 2020, 12-05, Volume: 143, Issue:11

    Topics: Aged; Antiparkinson Agents; Benserazide; Computer Simulation; Conditioning, Operant; Dopamine Agonists; Drug Combinations; Female; Humans; Learning; Levodopa; Male; Middle Aged; Motivation; Parkinson Disease; Phenotype; Punishment; Reward; Tremor

2020
Levodopa/dopa decarboxylase inhibitor associated microscopic colitis: An under-recognized drug reaction.
    Parkinsonism & related disorders, 2021, Volume: 86

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Benserazide; Carbidopa; Cohort Studies; Colitis, Microscopic; Drug Combinations; Enzyme Inhibitors; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Retrospective Studies

2021
Frailty phenotype and the role of levodopa challenge test in geriatric inpatients with mild parkinsonian signs.
    Biogerontology, 2017, Volume: 18, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Benserazide; Case-Control Studies; Cross-Sectional Studies; Dopamine; Dopamine Agents; Drug Combinations; Female; Frail Elderly; Frailty; Geriatric Assessment; Geriatrics; Humans; Inpatients; Levodopa; Male; Parkinson Disease; Phenotype; Poland; Predictive Value of Tests; Prevalence; Severity of Illness Index

2017
Degeneration of the corticofugal tract from the secondary motor area in a Parkinson's disease patient with limb-kinetic apraxia: A case report.
    Medicine, 2017, Volume: 96, Issue:50

    Topics: Anisotropy; Antiparkinson Agents; Benserazide; Diffusion Tensor Imaging; Drug Combinations; Female; Humans; Levodopa; Middle Aged; Motor Cortex; Muscle Rigidity; Muscular Atrophy, Spinal; Parkinson Disease; Positron-Emission Tomography; Tremor

2017
The nature of postural tremor in Parkinson disease.
    Neurology, 2018, 03-27, Volume: 90, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Benserazide; Cluster Analysis; Dopamine; Drug Combinations; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; Muscle, Skeletal; Parkinson Disease; Posture; Prevalence; Rest; Tremor

2018
Cortical response to levodopa in Parkinson's disease patients with dyskinesias.
    The European journal of neuroscience, 2018, Volume: 48, Issue:6

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Benserazide; Brain; Drug Combinations; Dyskinesia, Drug-Induced; Electroencephalography; Female; Humans; Levodopa; Male; Middle Aged; Motor Cortex; Parkinson Disease; Transcranial Magnetic Stimulation

2018
A multiparametric analysis of the synergistic impact of anti-Parkinson's drugs on the fibrillation of human serum albumin.
    Biochimica et biophysica acta. Proteins and proteomics, 2019, Volume: 1867, Issue:3

    Topics: Amyloid; Benserazide; Cell Line, Tumor; Cell Survival; Dopamine Agents; Drug Combinations; Humans; Levodopa; Parkinson Disease; Protein Aggregates; Serum Albumin, Human

2019
Sit-to-walk performance in Parkinson's disease: A comparison between faller and non-faller patients.
    Clinical biomechanics (Bristol, Avon), 2019, Volume: 63

    Topics: Accidental Falls; Aged; Aged, 80 and over; Benserazide; Case-Control Studies; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Movement; Parkinson Disease; Postural Balance; Quality of Life; Sensitivity and Specificity; Sitting Position; Walking

2019
Pharmaceutical quality of seven generic Levodopa/Benserazide products compared with original Madopar® / Prolopa®.
    BMC pharmacology & toxicology, 2013, Apr-23, Volume: 14

    Topics: Benserazide; Capsules; Color; Dopamine Agents; Drug Combinations; Drugs, Generic; Humans; Levodopa; Parkinson Disease; Practice Patterns, Physicians'; Product Surveillance, Postmarketing; Quality Control; Tablets; Therapeutic Equivalency

2013
Zoophilia and Parkinson's disease.
    Parkinsonism & related disorders, 2013, Volume: 19, Issue:12

    Topics: Antiparkinson Agents; Benserazide; Drug Combinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Selegiline; Sexual Dysfunctions, Psychological

2013
L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum.
    Scientific reports, 2014, Jan-16, Volume: 4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benserazide; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Combinations; Dyskinesias; Female; Levodopa; Macaca mulatta; Male; Parkinson Disease

2014
Levodopa/benserazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats.
    Scientific reports, 2014, Dec-16, Volume: 4

    Topics: Adrenergic Agents; Animals; Benserazide; Blotting, Western; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Dopamine Agents; Drug Combinations; Dyskinesias; Female; Fluorescent Antibody Technique; Lactic Acid; Levodopa; Microspheres; Neurons; Oxidopamine; Parkinson Disease; Phosphoproteins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; tau Proteins; Transcription Factors

2014
Beneficial antioxidant properties of betaine against oxidative stress mediated by levodopa/benserazide in the brain of rats.
    The journal of physiological sciences : JPS, 2015, Volume: 65, Issue:3

    Topics: Animals; Antioxidants; Benserazide; Betaine; Brain; Dopamine; Dopamine Agents; Drug Combinations; Glutathione; Glutathione Peroxidase; Humans; Hyperhomocysteinemia; Levodopa; Lipid Peroxidation; Male; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2015
Neuroprotective effect of combined therapy with hyperbaric oxygen and madopar on 6-hydroxydopamine-induced Parkinson's disease in rats.
    Neuroscience letters, 2015, Jul-23, Volume: 600

    Topics: Animals; Apomorphine; Benserazide; Combined Modality Therapy; Drug Combinations; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Hyperbaric Oxygenation; Levodopa; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase

2015
Behavioural Assessment of the A2a/NR2B Combination in the Unilateral 6-OHDA-Lesioned Rat Model: A New Method to Examine the Therapeutic Potential of Non-Dopaminergic Drugs.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adenosine A2 Receptor Antagonists; Animals; Benserazide; Benzothiazoles; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Combinations; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Receptors, N-Methyl-D-Aspartate

2015
Pharmacodynamics of a low subacute levodopa dose helps distinguish between multiple system atrophy with predominant Parkinsonism and Parkinson's disease.
    Journal of neurology, 2016, Volume: 263, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Benserazide; Diagnosis, Differential; Dopamine Agents; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Motor Activity; Multiple System Atrophy; Parkinson Disease; Retrospective Studies

2016
Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system.
    Neuroscience letters, 2016, Mar-11, Volume: 616

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benserazide; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Combinations; Hydrazines; Levodopa; Male; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Oxadiazoles; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase

2016
The effect of levodopa benserazide hydrochloride on homocysteinemia levels in patients with Parkinson's disease and treatment of hyperhomocysteinemia.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:11

    Topics: Antiparkinson Agents; Benserazide; Dopamine Agents; Drug Combinations; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Parkinson Disease

2016
Severe gastroparesis in a patient with advanced Parkinson's disease.
    Wiener klinische Wochenschrift, 2009, Volume: 121, Issue:13-14

    Topics: Aged, 80 and over; Benserazide; Dopamine Agents; Drug Combinations; Enzyme Inhibitors; Follow-Up Studies; Gastroparesis; Humans; Levodopa; Male; Parkinson Disease; Radiography, Abdominal; Time Factors; Tomography, X-Ray Computed; Treatment Outcome

2009
Complementary acupuncture treatment increases cerebral metabolism in patients with Parkinson's disease.
    The International journal of neuroscience, 2009, Volume: 119, Issue:8

    Topics: Acupuncture Therapy; Aged; Antiparkinson Agents; Benserazide; Brain Chemistry; Combined Modality Therapy; Drug Combinations; Energy Metabolism; Female; Fluorodeoxyglucose F18; Glucose; Humans; Image Processing, Computer-Assisted; Levodopa; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals

2009
Hyperthyroidism "masked" the levodopa response in newly diagnosed Parkinson's disease patients.
    Parkinsonism & related disorders, 2010, Volume: 16, Issue:10

    Topics: Antiparkinson Agents; Antithyroid Agents; Benserazide; Carbimazole; Drug Combinations; Female; Graves Disease; Heart Rate; Humans; Hyperthyroidism; Levodopa; Male; Middle Aged; Parkinson Disease; Thyroxine

2010
Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benserazide; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Partial Agonism; Dyskinesia, Drug-Induced; Hyperkinesis; Levodopa; Male; Microdialysis; Motor Activity; Oxazepines; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists

2010
Analysis of differences between physiological and pathological tremor of human fingers.
    Bulletin of experimental biology and medicine, 2010, Volume: 149, Issue:4

    Topics: Antiparkinson Agents; Benserazide; Drug Combinations; Electromyography; Fingers; Humans; Isometric Contraction; Levodopa; Middle Aged; Parkinson Disease; Tremor

2010
[Combined (surgical and drug) therapy of parkinsonism].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984, Volume: 84, Issue:8

    Topics: Benserazide; Catecholamines; Combined Modality Therapy; Diencephalon; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease; Stereotaxic Techniques

1984
L-deprenyl in the treatment of Parkinson's disease.
    Journal of neural transmission. Supplementum, 1983, Volume: 19

    Topics: Aged; Benserazide; Disability Evaluation; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Levodopa; Middle Aged; Motor Skills; Parkinson Disease; Phenethylamines; Selegiline

1983
Clinical evaluation of deprenyl (selegiline) in the treatment of Parkinson's disease.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 95

    Topics: Aged; Benserazide; Disability Evaluation; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenethylamines; Selegiline

1983
[Madopar in the treatment of paralysis agitans: II. TRH activation test, EMG examination and HVA level in cerebrospinal fluid before and after treatment].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1980, Volume: 13, Issue:4

    Topics: Aged; Benserazide; Drug Combinations; Electromyography; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Thyrotropin; Thyrotropin-Releasing Hormone

1980
Thyrotrophin and prolactin responses to thyrotrophin-releasing hormone in patients with Parkinson's disease.
    Acta endocrinologica, 1982, Volume: 99, Issue:3

    Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1982
Prolactin response to acute administration of different L-dopa plus decarboxylase inhibitors in Parkinson's disease.
    Neuropsychobiology, 1982, Volume: 8, Issue:2

    Topics: Aged; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Rats

1982
Growth hormone and prolactin stimulation by Madopar in Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:12

    Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Drug Combinations; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Lisuride; Male; Middle Aged; Parkinson Disease; Prolactin; Receptors, Dopamine

1981
[Benefits of a new galenic form of levodopa and benserazide in the treatment of patients with Parkinson disease].
    Praxis, 1995, Oct-24, Volume: 84, Issue:43

    Topics: Aged; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Combinations; Enzyme Inhibitors; Humans; Levodopa; Middle Aged; Parkinson Disease

1995
[Effectiveness of slow release L-DOPA/benserazide in treatment of end-of-dose akinesia in Parkinson disease].
    Der Nervenarzt, 1995, Volume: 66, Issue:12

    Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease

1995
Clinical implications of sustained dopaminergic stimulation.
    Clinical neuropharmacology, 1994, Volume: 17 Suppl 2

    Topics: Aged; Benserazide; Carbidopa; Delayed-Action Preparations; Dopamine Agonists; Drug Combinations; Dyskinesia, Drug-Induced; Follow-Up Studies; Humans; Levodopa; Lisuride; Parkinson Disease; Reaction Time

1994
[Madopar: more than 20 years].
    Revista de neurologia, 1997, Volume: 25, Issue:148

    Topics: Antiparkinson Agents; Benserazide; Dopamine Agents; Drug Combinations; History, 20th Century; Humans; Levodopa; Parkinson Disease

1997
Highlights of the North American and European experiences.
    Neurology, 1998, Volume: 50, Issue:5 Suppl 5

    Topics: Antiparkinson Agents; Benserazide; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Dopamine Agents; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Enzyme Inhibitors; Europe; Humans; Levodopa; Nitrophenols; North America; Parkinson Disease; Randomized Controlled Trials as Topic; Tolcapone

1998
The reach-to-grasp movement in Parkinson's disease before and after dopaminergic medication.
    Neuropsychologia, 2000, Volume: 38, Issue:1

    Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Psychomotor Performance; Reaction Time; Receptors, Dopamine

2000
[A case of delusional jealousy in Parkinson disease ].
    Der Nervenarzt, 2001, Volume: 72, Issue:3

    Topics: Antiparkinson Agents; Benserazide; Delusions; Dose-Response Relationship, Drug; Drug Combinations; Humans; Jealousy; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced

2001
Paradoxical akinetic response to apomorphine in parkinsonism.
    Journal of neurology, neurosurgery, and psychiatry, 1992, Volume: 55, Issue:5

    Topics: Apomorphine; Benserazide; Drug Combinations; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Injections, Subcutaneous; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease

1992
Controlled-release delivery of L-dopa associated with nonfatal hyperthermia, rigidity, and autonomic dysfunction.
    Neurology, 1991, Volume: 41, Issue:6

    Topics: Adult; Autonomic Nervous System Diseases; Benserazide; Delayed-Action Preparations; Drug Combinations; Fever; Humans; Levodopa; Male; Muscle Rigidity; Parkinson Disease

1991
The clinical efficacy of oral levodopa methyl ester solution in reversing afternoon "off" periods in Parkinson's disease.
    Clinical neuropharmacology, 1991, Volume: 14, Issue:3

    Topics: Administration, Oral; Aged; Benserazide; Drug Combinations; Humans; Levodopa; Middle Aged; Parkinson Disease

1991
Long-term treatment with Madopar HBS in parkinsonians with fluctuations.
    Advances in neurology, 1990, Volume: 53

    Topics: Aged; Benserazide; Carboxy-Lyases; Delayed-Action Preparations; Drug Combinations; Follow-Up Studies; Humans; Levodopa; Long-Term Care; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease

1990
Severity of Parkinson's disease is a risk factor for peak-dose dyskinesia.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:3

    Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease

1990
Treatment of early Parkinson's disease with controlled-release levodopa preparations.
    Neurology, 1989, Volume: 39, Issue:11 Suppl 2

    Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease

1989
Enantiomeric composition of urinary salsolinol in parkinsonian patients after Madopar.
    Journal of neural transmission. Parkinson's disease and dementia section, 1989, Volume: 1, Issue:4

    Topics: Aged; Aged, 80 and over; Benserazide; Drug Combinations; Female; Humans; Hydrazines; Isoquinolines; Levodopa; Male; Middle Aged; Parkinson Disease; Stereoisomerism

1989
Disability profiles and objective quantitative assessment in Parkinson's disease.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:3

    Topics: Adult; Aged; Benserazide; Carbidopa; Disability Evaluation; Drug Combinations; Female; Humans; Levodopa; Locomotion; Male; Middle Aged; Parkinson Disease; Posture; Psychomotor Performance; Reaction Time

1989
[Motor fluctuations in Parkinson's disease: the "New frontier" of therapeutic success. A Roche Laboratory seminar].
    La Revue du praticien, 1989, Mar-09, Volume: 39, Issue:8

    Topics: Antiparkinson Agents; Benserazide; Drug Administration Schedule; Drug Combinations; Humans; Levodopa; Movement Disorders; Parkinson Disease

1989
Induction of aromatic-L-amino acid decarboxylase by decarboxylase inhibitors in idiopathic parkinsonism.
    Annals of neurology, 1989, Volume: 25, Issue:6

    Topics: Aged; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Carboxy-Lyases; Drug Combinations; Drug Therapy, Combination; Enzyme Induction; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors

1989
Pregnancy and parkinsonism. A case report without problem.
    Clinical neuropharmacology, 1989, Volume: 12, Issue:3

    Topics: Adult; Benserazide; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Parkinson Disease; Pregnancy; Pregnancy Complications

1989
Treatment of idiopathic parkinsonism with L-dopa in the absence and presence of decarboxylase inhibitors: effects on plasma levels of L-dopa, dopa decarboxylase, catecholamines and 3-O-methyl-dopa.
    Journal of neurology, 1989, Volume: 236, Issue:4

    Topics: Administration, Oral; Aged; Benserazide; Carboxy-Lyases; Catecholamines; Dopa Decarboxylase; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Longitudinal Studies; Male; Middle Aged; Parkinson Disease; Phenytoin; Time Factors; Tyrosine

1989
[The concentration of homovanillic acid and leucine-enkephalin in the lumbar CSF of patients with Parkinson's disease before and after madopar treatment].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1989, Volume: 22, Issue:2

    Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Drug Combinations; Enkephalin, Leucine; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease

1989
Painful Parkinson's disease.
    Lancet (London, England), 1986, Jun-14, Volume: 1, Issue:8494

    Topics: Acute Disease; Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Administration Schedule; Drug Combinations; Dyskinesia, Drug-Induced; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Motor Activity; Pain; Parkinson Disease; Time Factors

1986
Optimization of symptomatic therapy in Parkinson's disease.
    IEEE transactions on bio-medical engineering, 1989, Volume: 36, Issue:3

    Topics: Benserazide; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Computer-Assisted; Humans; Hydrazines; Levodopa; Models, Biological; Parkinson Disease; Reaction Time; Therapy, Computer-Assisted

1989
Effect of hypoglycaemia, TRH and levodopa on plasma growth hormone, prolactin, thyrotropin and cortisol in Parkinson's disease before and during therapy.
    Journal of neurology, 1986, Volume: 233, Issue:3

    Topics: Adult; Aged; Benserazide; Dopamine; Drug Combinations; Female; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Insulin; Levodopa; Male; Middle Aged; Parkinson Disease; Pituitary-Adrenal System; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone

1986
MPTP: clinical implications.
    Journal of neural transmission. Supplementum, 1986, Volume: 20

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Basal Ganglia; Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenethylamines; Pyridines; Selegiline

1986
Parkinson's disease in the elderly: a long-term efficacy study of levodopa/benserazide combination therapy.
    Pharmatherapeutica, 1986, Volume: 4, Issue:9

    Topics: Aged; Aged, 80 and over; Benserazide; Bromocriptine; Confusion; Drug Combinations; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Middle Aged; Parkinson Disease

1986
Effect of (-)deprenyl in long-term treatment of Parkinson's disease. A 10-years experience.
    Journal of neural transmission. Supplementum, 1986, Volume: 22

    Topics: Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenethylamines; Retrospective Studies; Selegiline; Time Factors

1986
(-)Deprenyl in the treatment of decompensated Parkinson's disease.
    Journal of neural transmission. Supplementum, 1986, Volume: 22

    Topics: Benserazide; Drug Combinations; Humans; Hydrazines; Levodopa; Movement Disorders; Parkinson Disease; Phenethylamines; Selegiline

1986
[Therapeutic strategies and tactics in parkinsonism].
    Wiener medizinische Wochenschrift (1946), 1986, Aug-31, Volume: 136, Issue:15-16

    Topics: Amantadine; Antidepressive Agents; Antiparkinson Agents; Benserazide; Carbidopa; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Humans; Levodopa; Lisuride; Motor Skills; Parkinson Disease; Selegiline; Sleep Initiation and Maintenance Disorders

1986
Madopar HBS in Parkinson patients with nocturnal akinesia.
    Clinical neurology and neurosurgery, 1988, Volume: 90, Issue:1

    Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors

1988
Outpatient treatment of Parkinson's disease.
    European neurology, 1988, Volume: 28, Issue:3

    Topics: Ambulatory Care; Benserazide; Bromocriptine; Carboxy-Lyases; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Levodopa; Parkinson Disease; Retrospective Studies

1988
Madopar HBS. International workshop on the 'on-off-phenomenon in Parkinson's disease. New possibilities for its management. Agno, November 14-16, 1985.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Benserazide; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease

1987
Madopar HBS in the long-term treatment of parkinsonian patients with fluctuations in disability.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Aged; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors

1987
A sustained-release formulation of L-dopa (Madopar HBS) in the treatment of nocturnal and early-morning disabilities in Parkinson's disease.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Benserazide; Circadian Rhythm; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Substitution of standard Madopar by Madopar HBS in parkinsonians with fluctuations.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Aged; Aged, 80 and over; Benserazide; Biological Availability; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Madopar HBS: slow-release levodopa and benserazide in parkinsonian patients presenting marked fluctuations in symptoms on standard L-dopa treatment.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Therapeutic value of Madopar HBS: judgment after 2 years experience.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1987
Management of Parkinson's disease in general practice.
    Scottish medical journal, 1986, Volume: 31, Issue:2

    Topics: Aged; Benserazide; Bromocriptine; Carbidopa; Drug Combinations; Family Practice; Humans; Levodopa; Medical Audit; Parkinson Disease

1986
Individual levodopa therapy in Parkinson's disease.
    Advances in neurology, 1987, Volume: 45

    Topics: Benserazide; Chromatography, High Pressure Liquid; Drug Combinations; Gait; Humans; Levodopa; Parkinson Disease; Psychomotor Performance

1987
[Drug therapy of Parkinson's disease].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1985, Volume: 18, Issue:4

    Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

1985
[Clinical significance of cramps of the lower extremities in patients with parkinsonism].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1985, Volume: 18, Issue:4

    Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Leg; Levodopa; Male; Middle Aged; Muscle Cramp; Parkinson Disease

1985