ro 5-4864 has been researched along with Muscle Contraction in 10 studies
4'-chlorodiazepam: selectively binds peripheral benzodiazepine receptor
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined the actions of Ro5-4684 (parachlorodiazepam) and midazolam on guinea pig tracheal smooth muscle contraction." | 3.67 | Peripheral type benzodiazepine receptor and airway smooth muscle relaxation. ( Miller, LG; Raeburn, D; Summer, WR, 1988) |
| "PK 11195 which has been shown to inhibit the binding of Ro 5-4864 to cardiac muscle did not antagonize this vasodilatory effect of Ro 5-4864 but increased coronary flow by itself." | 1.27 | Benzodiazepine Ro 5-4864 increases coronary flow. ( French, JF; Grupp, IL; Matlib, MA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monasterolo, LA | 1 |
| Ochoa, JE | 1 |
| Trumper, L | 1 |
| Elías, MM | 1 |
| Chiou, LC | 1 |
| Chang, CC | 1 |
| Escubedo, E | 2 |
| Pallas, M | 2 |
| Nuñez, C | 1 |
| Camarasa, J | 2 |
| Devillier, P | 2 |
| Candenas, ML | 2 |
| Naline, E | 2 |
| Advenier, C | 2 |
| Adzet, T | 1 |
| Holck, M | 1 |
| Osterrieder, W | 1 |
| Raeburn, D | 1 |
| Miller, LG | 1 |
| Summer, WR | 1 |
| Bolger, GT | 1 |
| Newman, AH | 1 |
| Rice, KC | 1 |
| Lueddens, HW | 1 |
| Basile, AS | 1 |
| Skolnick, P | 1 |
| Grupp, IL | 1 |
| French, JF | 1 |
| Matlib, MA | 1 |
10 other studies available for ro 5-4864 and Muscle Contraction
| Article | Year |
|---|---|
Vascular and tubular actions of diazepam in isolated and perfused rat kidney.
Topics: Animals; Benzodiazepinones; Biological Transport, Active; Blood Vessels; Clonazepam; Convulsants; Di | 1995 |
Pharmacological relevance of peripheral type benzodiazepine receptors on motor nerve and skeletal muscle.
Topics: Animals; Benzodiazepinones; Diaphragm; Electric Stimulation; Electrophysiology; Female; Flumazenil; | 1994 |
Effects of Ro 5-4864 and PK 11195 in rat duodenum and vas deferens.
Topics: Animals; Benzodiazepinones; Calcium; Carbachol; Cholera Toxin; Duodenum; In Vitro Techniques; Isoqui | 1992 |
Influence of benzodiazepines on the response of the guinea-pig isolated trachea to the contractile action of adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Epithelium; Guinea Pigs; | 1992 |
Contractile effect of alpha,beta-methylene ATP on the guinea-pig isolated trachea.
Topics: 2-Chloroadenosine; Adenosine Triphosphate; Animals; Benzodiazepinones; Clonazepam; Diazepam; Drug Sy | 1992 |
Peripheral benzodiazepines potentiate the effect of adenosine in rat vas deferens.
Topics: Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Drug Synergism; Electric Stimulation; Isoqui | 1991 |
The peripheral, high affinity benzodiazepine binding site is not coupled to the cardiac Ca2+ channel.
Topics: Action Potentials; Animals; Benzodiazepinones; Calcium Channel Blockers; Guinea Pigs; Heart; In Vitr | 1985 |
Peripheral type benzodiazepine receptor and airway smooth muscle relaxation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Calcium; Convulsants; Guinea Pigs; | 1988 |
Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Benzodiazepine Ro 5-4864 increases coronary flow.
Topics: Animals; Benzodiazepinones; Clonazepam; Convulsants; Coronary Circulation; Heart Rate; In Vitro Tech | 1987 |