ro 5-4864 has been researched along with Inflammation in 8 studies
4'-chlorodiazepam: selectively binds peripheral benzodiazepine receptor
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "diazepam treatment reduced the magnitude of the increase in vascular permeability caused by carrageenin; 5." | 5.31 | Reduction of acute inflammation in rats by diazepam: role of peripheral benzodiazepine receptors and corticosterone. ( Lazzarini, R; Malucelli, BE; Palermo-Neto, J, 2001) |
| "Brain injury after subarachnoid hemorrhage (SAH) is closely related to microglia/macrophages-induced neuroinflammation." | 1.56 | TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice. ( Chen, L; Du, F; Feng, Y; Guo, K; Jiang, Y; Peng, J; Xie, Y; Zhang, L; Zhang, X; Zhou, J, 2020) |
| "diazepam treatment reduced the magnitude of the increase in vascular permeability caused by carrageenin; 5." | 1.31 | Reduction of acute inflammation in rats by diazepam: role of peripheral benzodiazepine receptors and corticosterone. ( Lazzarini, R; Malucelli, BE; Palermo-Neto, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Zhou, J | 1 |
| Zhang, X | 1 |
| Peng, J | 1 |
| Xie, Y | 1 |
| Du, F | 1 |
| Guo, K | 1 |
| Feng, Y | 1 |
| Zhang, L | 1 |
| Chen, L | 1 |
| Jiang, Y | 1 |
| Bader, S | 1 |
| Wolf, L | 1 |
| Milenkovic, VM | 1 |
| Gruber, M | 1 |
| Nothdurfter, C | 1 |
| Rupprecht, R | 1 |
| Wetzel, CH | 1 |
| Hernstadt, H | 1 |
| Wang, S | 1 |
| Lim, G | 1 |
| Mao, J | 1 |
| Taupin, V | 1 |
| Toulmond, S | 1 |
| Benavides, J | 1 |
| Gogusev, J | 1 |
| Descamps-Latscha, B | 1 |
| Zavala, F | 1 |
| Torres, SR | 2 |
| Nardi, GM | 2 |
| Ferrara, P | 2 |
| Ribeiro-do-Valle, RM | 2 |
| Farges, RC | 2 |
| Fröde, TS | 1 |
| Vita, N | 1 |
| Reeb, R | 1 |
| Lazzarini, R | 1 |
| Malucelli, BE | 1 |
| Palermo-Neto, J | 1 |
8 other studies available for ro 5-4864 and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Topics: Animals; Anti-Inflammatory Agents; Benzodiazepinones; Brain Injuries; Disease Models, Animal; Inflam | 2020 |
Differential effects of TSPO ligands on mitochondrial function in mouse microglia cells.
Topics: Animals; Benzodiazepinones; Cell Line; Inflammation; Isoquinolines; Ligands; Lipopolysaccharides; Mi | 2019 |
Spinal translocator protein (TSPO) modulates pain behavior in rats with CFA-induced monoarthritis.
Topics: Animals; Arthritis, Experimental; Behavior, Animal; Benzodiazepinones; Carrier Proteins; Convulsants | 2009 |
Regulation of neural and peripheral cytokine production by benzodiazepines and endogenous anxiogenic peptides.
Topics: Animals; Benzodiazepinones; Brain Injuries; Carrier Proteins; Cerebral Cortex; Cytokines; Diazepam B | 1994 |
Potential role of peripheral benzodiazepine receptors in inflammatory responses.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Benzodiazepinones; Carrageenan; Dose-Response Rela | 1999 |
Anti-inflammatory effects of peripheral benzodiazepine receptor ligands in two mouse models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Benzodiazepinones; Disease Models, Animal; | 2000 |
Reduction of acute inflammation in rats by diazepam: role of peripheral benzodiazepine receptors and corticosterone.
Topics: Acute Disease; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzodiazepinones; C | 2001 |