ro 5-4864 has been researched along with Cardiac Hypertrophy in 1 studies
4'-chlorodiazepam: selectively binds peripheral benzodiazepine receptor
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoprenaline-induced cardiac hypertrophy was associated with increased expression of beta myosin heavy chain, which was also prevented by Ro5-4864." | 1.36 | Peripheral benzodiazepine receptor ligand Ro5-4864 inhibits isoprenaline-induced cardiac hypertrophy in rats. ( Dinda, AK; Enjamoori, R; Jaiswal, A; Kumar, S; Maulik, SK; Seth, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaiswal, A | 1 |
| Kumar, S | 1 |
| Enjamoori, R | 1 |
| Seth, S | 1 |
| Dinda, AK | 1 |
| Maulik, SK | 1 |
1 other study available for ro 5-4864 and Cardiac Hypertrophy
| Article | Year |
|---|---|
Peripheral benzodiazepine receptor ligand Ro5-4864 inhibits isoprenaline-induced cardiac hypertrophy in rats.
Topics: Animals; Antioxidants; Benzodiazepinones; Cardiomegaly; Disease Models, Animal; Dose-Response Relati | 2010 |