ro 5-4864 has been researched along with Breast Cancer in 6 studies
4'-chlorodiazepam: selectively binds peripheral benzodiazepine receptor
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, we investigated the effect of the high-affinity PBR ligands Ro5-4684 and PK 11195 on tamoxifen (TAM)-induced apoptosis in MCF-7 and BT-20 breast cancer cell lines." | 7.71 | Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells. ( Knecht, R; Kuhl, H; Roller, M; Sänger, N; Strohmeier, R, 2002) |
| " Therefore, we investigated the effect of the high-affinity PBR ligands Ro5-4684 and PK 11195 on tamoxifen (TAM)-induced apoptosis in MCF-7 and BT-20 breast cancer cell lines." | 3.71 | Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells. ( Knecht, R; Kuhl, H; Roller, M; Sänger, N; Strohmeier, R, 2002) |
| "Control of breast cancer development by consumption of dietary soy protein has been linked to down-regulation of the expression of TSPO-mediated angiogenic signaling molecules." | 1.38 | Translocator protein (TSPO) in breast cancer. ( Das, SK; Mukherjee, S, 2012) |
| "Biosynthesis of PC was increased in breast cancer cell lines upon treatment." | 1.33 | Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonist. ( Akech, J; Das, SK; Sinha Roy, S, 2005) |
| "Diazepam was able to displace [3H]Ro5-4864 from binding only at high concentrations (>1 microM), while ODN did not compete for PBR binding." | 1.30 | Specific binding of benzodiazepines to human breast cancer cell lines. ( Beinlich, A; Kaufmann, M; Kuhl, H; Strohmeier, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, X | 1 |
| Gallo, KA | 1 |
| Mukherjee, S | 1 |
| Das, SK | 2 |
| Akech, J | 1 |
| Sinha Roy, S | 1 |
| Carmel, I | 1 |
| Fares, FA | 1 |
| Leschiner, S | 1 |
| Scherübl, H | 1 |
| Weisinger, G | 1 |
| Gavish, M | 1 |
| Beinlich, A | 1 |
| Strohmeier, R | 2 |
| Kaufmann, M | 1 |
| Kuhl, H | 2 |
| Roller, M | 1 |
| Sänger, N | 1 |
| Knecht, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Remimazolam Tosilate for General Anesthesia on Prognosis After Bladder Cancer Surgery: a Randomized Controlled Trial[NCT04532606] | Phase 4 | 1,128 participants (Anticipated) | Interventional | 2021-02-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for ro 5-4864 and Breast Cancer
| Article | Year |
|---|---|
The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration.
Topics: Acinar Cells; Apoptosis; Benzodiazepinones; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell | 2013 |
Translocator protein (TSPO) in breast cancer.
Topics: Animals; Benzodiazepinones; Breast Neoplasms; Cell Nucleus; Cell Proliferation; Cholesterol; Diacylg | 2012 |
Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonist.
Topics: Benzodiazepinones; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diacyl | 2005 |
Peripheral-type benzodiazepine receptors in the regulation of proliferation of MCF-7 human breast carcinoma cell line.
Topics: Antineoplastic Agents; Benzodiazepinones; Breast Neoplasms; Cell Cycle; Cell Division; DNA; GABA-A R | 1999 |
Specific binding of benzodiazepines to human breast cancer cell lines.
Topics: Benzodiazepinones; Breast Neoplasms; Cell Division; Convulsants; Diazepam; Dose-Response Relationshi | 1999 |
Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; Benzodiazepinones; Breast Neoplasms; Drug Interactions; | 2002 |