ro 5-4864 has been researched along with Astrocytoma in 1 studies
4'-chlorodiazepam: selectively binds peripheral benzodiazepine receptor
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of several benzodiazepines (diazepam, clonazepam, Ro 15-1788 and Ro 5-4864) on cell proliferation of 2 human gliomas were estimated in vitro by means of [3H]-thymidine uptake assay." | 3.67 | Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro. ( Kunert-Radek, J; Pawlikowski, M; Radek, A; Stepien, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pawlikowski, M | 1 |
| Kunert-Radek, J | 1 |
| Radek, A | 1 |
| Stepien, H | 1 |
1 other study available for ro 5-4864 and Astrocytoma
| Article | Year |
|---|---|
Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro.
Topics: Astrocytoma; Benzodiazepines; Benzodiazepinones; Cell Division; Clonazepam; Diazepam; Female; Flumaz | 1988 |