ro 48-8071 has been researched along with Craniofacial Abnormalities in 1 studies
Ro 48-8071: a cholesterol synthesis inhibitor; structure in first source
Ro 48-8071 : An aromatic ketone that is 2-fluoro-4'-bromobenzophenone in which the hydrogen at position 4 (meta to the fluoro group) is replaced by a 6-[methyl(prop-2-en-1-yl)amino]hexyl}oxy group. An inhibitor of lanosterol synthase.
Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quintana, AM | 1 |
| Hernandez, JA | 1 |
| Gonzalez, CG | 1 |
1 other study available for ro 48-8071 and Craniofacial Abnormalities
| Article | Year |
|---|---|
Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Benzophenones; Body Patterning; Cell Differentiatio | 2017 |