ro 48-8071 has been researched along with Carcinoma, Pancreatic Ductal in 1 studies
Ro 48-8071: a cholesterol synthesis inhibitor; structure in first source
Ro 48-8071 : An aromatic ketone that is 2-fluoro-4'-bromobenzophenone in which the hydrogen at position 4 (meta to the fluoro group) is replaced by a 6-[methyl(prop-2-en-1-yl)amino]hexyl}oxy group. An inhibitor of lanosterol synthase.
Carcinoma, Pancreatic Ductal: Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The morbidity and mortality of pancreatic cancer have been continuously increasing, causing seven deaths per 100,000 individuals/year." | 1.62 | Cholesterol biosynthesis inhibitor RO 48‑8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway. ( Ding, Z; Gu, Y; Huang, D; Luo, X; Qian, Y; Zhang, S; Zhou, H; Zhu, T, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, Z | 1 |
| Gu, Y | 1 |
| Huang, D | 1 |
| Zhou, H | 1 |
| Zhu, T | 1 |
| Luo, X | 1 |
| Zhang, S | 2 |
| Qian, Y | 1 |
1 other study available for ro 48-8071 and Carcinoma, Pancreatic Ductal
| Article | Year |
|---|---|
Cholesterol biosynthesis inhibitor RO 48‑8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway.
Topics: Animals; Benzophenones; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Cell | 2021 |