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ro 31-8220 and Thymoma

ro 31-8220 has been researched along with Thymoma in 1 studies

Ro 31-8220: a protein kinase C inhibitor

Thymoma: A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" Here we have examined the effects of two PKC inhibitors, staurosporine and the more selective agent Ro 31-8220, on IL1 responses in the murine thymoma line EL4."7.69Staurosporine, but not Ro 31-8220, induces interleukin 2 production and synergizes with interleukin 1alpha in EL4 thymoma cells. ( Mahon, TM; Matthews, JS; O'Neill, LA, 1997)
" Here we have examined the effects of two PKC inhibitors, staurosporine and the more selective agent Ro 31-8220, on IL1 responses in the murine thymoma line EL4."3.69Staurosporine, but not Ro 31-8220, induces interleukin 2 production and synergizes with interleukin 1alpha in EL4 thymoma cells. ( Mahon, TM; Matthews, JS; O'Neill, LA, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mahon, TM1
Matthews, JS1
O'Neill, LA1

Other Studies

1 other study available for ro 31-8220 and Thymoma

ArticleYear
Staurosporine, but not Ro 31-8220, induces interleukin 2 production and synergizes with interleukin 1alpha in EL4 thymoma cells.
    The Biochemical journal, 1997, Jul-01, Volume: 325 ( Pt 1)

    Topics: Animals; Cell Membrane; Cytosol; Drug Synergism; Enzyme Inhibitors; Indoles; Interleukin-1; Interleu

1997