ro 31-8220 has been researched along with Glial Cell Tumors in 5 studies
Ro 31-8220: a protein kinase C inhibitor
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we show that the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells due to phospholipid hydrolysis by phospholipase D (PLD) is not inhibited by rapamycin or PD98059, specific inhibitors respectively of p70 S6 kinase and MAPKK (MEK) and thus of MAPKAP kinase-1beta but is still completely blocked by Ro31-8220." | 7.69 | Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD. ( Beale, G; Mallon, B; Morreale, A; Rumsby, M; Watson, J, 1997) |
| " Here we show that the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells due to phospholipid hydrolysis by phospholipase D (PLD) is not inhibited by rapamycin or PD98059, specific inhibitors respectively of p70 S6 kinase and MAPKK (MEK) and thus of MAPKAP kinase-1beta but is still completely blocked by Ro31-8220." | 3.69 | Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD. ( Beale, G; Mallon, B; Morreale, A; Rumsby, M; Watson, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CY | 1 |
| Ma, KH | 1 |
| Wang, JK | 1 |
| Tung, YL | 1 |
| Chueh, SH | 1 |
| Mallon, BS | 2 |
| Thompson, HJ | 2 |
| Turner, RA | 1 |
| Holden, CM | 1 |
| Rumsby, MG | 2 |
| Litherland, GJ | 1 |
| Morreale, A | 1 |
| Mallon, B | 1 |
| Beale, G | 1 |
| Watson, J | 1 |
| Rumsby, M | 1 |
| Uehara, T | 1 |
| Baba, I | 1 |
| Nomura, Y | 1 |
5 other studies available for ro 31-8220 and Glial Cell Tumors
| Article | Year |
|---|---|
Inhibition of protein kinase C promotes differentiation of neuroblastoma × glioma NG108-15 hybrid cells.
Topics: Animals; Carbazoles; Cell Count; Cell Differentiation; Cell Line, Tumor; Cell Shape; Enzyme Inhibito | 2011 |
Protein kinase C activation of phospholipase D in C6 glioma cells.
Topics: Alkaloids; Animals; Cell Line; Enzyme Activation; Glioma; Indoles; Phorbol Esters; Phospholipase D; | 1993 |
Staurosporine and its derivative RO31-8220, both inhibitors of protein kinase C, have different effects on C6 glioma cell morphology.
Topics: Alkaloids; Cell Line; Glioma; Indoles; Molecular Weight; Phosphoproteins; Protein Kinase C; Staurosp | 1993 |
Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD.
Topics: Androstadienes; Animals; Choline; Enzyme Inhibitors; Ethanolamine; Flavonoids; Glioma; Indoles; Phos | 1997 |
Induction of cytokine-induced neutrophil chemoattractant in response to various stresses in rat C6 glioma cells.
Topics: Animals; Astrocytes; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; CCAAT-Enhancer-Bin | 1998 |