ro-16-0154 and MELAS-Syndrome

ro-16-0154 has been researched along with MELAS-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for ro-16-0154 and MELAS-Syndrome

Article	Year
Findings of 123I-iomazenil SPECT during and after stroke-like episodes in a patient with MELAS. Clinical nuclear medicine, 2014, Volume: 39, Issue:6 Reduced cortical benzodiazepine receptor binding potential in late images of I-iomazenil SPECT indicates neuronal damage in the cortex. We present the case of a 31-year-old woman with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had focal seizures in the right hand. FLAIR imaging in the ictal state revealed a high-intensity lesion in the left post-central gyrus, while I-iomazenil SPECT showed decreased tracer uptake in this lesion. The lesion completely disappeared on FLAIR imaging performed 1 month after the focal seizures; in contrast, I-iomazenil SPECT still revealed a significant decrease in tracer uptake in this lesion. Topics: Adult; Female; Flumazenil; Humans; Iodine Radioisotopes; MELAS Syndrome; Stroke; Tomography, Emission-Computed, Single-Photon	2014

Article

Year

Findings of 123I-iomazenil SPECT during and after stroke-like episodes in a patient with MELAS.

Clinical nuclear medicine, 2014, Volume: 39, Issue:6

Reduced cortical benzodiazepine receptor binding potential in late images of I-iomazenil SPECT indicates neuronal damage in the cortex. We present the case of a 31-year-old woman with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had focal seizures in the right hand. FLAIR imaging in the ictal state revealed a high-intensity lesion in the left post-central gyrus, while I-iomazenil SPECT showed decreased tracer uptake in this lesion. The lesion completely disappeared on FLAIR imaging performed 1 month after the focal seizures; in contrast, I-iomazenil SPECT still revealed a significant decrease in tracer uptake in this lesion.

Topics: Adult; Female; Flumazenil; Humans; Iodine Radioisotopes; MELAS Syndrome; Stroke; Tomography, Emission-Computed, Single-Photon

2014