ro-16-0154 and Intracranial-Aneurysm

Early and late images of. A woman aged 77 years presented with progression of cognitive decline, gait disturbance, and urinary incontinence. She had a medical history of epilepsy and subarachnoid hemorrhage due to a ruptured left posterior cerebral artery aneurysm, treated conservatively when she was age 56 years. Magnetic resonance imaging revealed a mass lesion in the pineal region, which showed a target sign with gadolinium-based contrast agents, causing obstructive hydrocephalus owing to compression of the cerebral aqueduct. A right vertebral angiogram confirmed the presence of a partially thrombosed giant aneurysm at the left posterior cerebral artery. To rule out the involvement of nonconvulsive status epilepticus in her pathology, we performed. The findings in the present case indicate that

Topics: Aged; Cell Survival; Cerebrovascular Circulation; Cognitive Dysfunction; Female; Flumazenil; Frontal Lobe; Gait Disorders, Neurologic; Humans; Hydrocephalus; Intracranial Aneurysm; Magnetic Resonance Imaging; Neurons; Thrombosis; Tomography, Emission-Computed, Single-Photon; Urinary Incontinence

Many studies of external-internal carotid artery (EC-IC) bypass as cerebral revascularization for unclippable internal carotid artery (ICA) aneurysms have reported surgical outcomes, including bypass patency and aneurysm resolution. However, no previous studies have assessed the long-term outcomes of cerebral blood flow (CBF), brain neural density, and cognition. The purpose of the present study was to evaluate the long-term outcomes of CBF and neurotransmitter receptor function using early and late images of iodine-123 (. We performed a prospective observational study of 11 patients who had undergone superficial temporal artery-middle cerebral artery bypass or bypass using a saphenous vein graft for symptomatic aneurysms in the cavernous portion of the ICA. One patient experienced extensive infarction and, therefore, did not undergo postoperative testing.. None of 10 patients who had undergone EC-IC bypass showed reductions in CBF and brain neural density. In addition, the neuropsychological test scores had not changed significantly from preoperatively to postoperatively.. Using early and late

Topics: Aged; Aged, 80 and over; Brain; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Revascularization; Cerebrovascular Circulation; Cognition; Female; Flumazenil; Humans; Intracranial Aneurysm; Longitudinal Studies; Middle Aged; Middle Cerebral Artery; Prospective Studies; Receptors, GABA-A; Saphenous Vein; Temporal Arteries; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vascular Grafting