ro-16-0154 has been researched along with Hepatic-Encephalopathy* in 1 studies
1 other study(ies) available for ro-16-0154 and Hepatic-Encephalopathy
Article | Year |
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[Results of displacement studies on benzodiazepine receptors (123I-iomazenil and flumazenil)].
SPECT studies with 123I-iomazenil were performed in 14 patients with hepatic encephalopathy. The activity concentration in the brain decreases spontaneously by 10 to 20% within 80 min, in the nasal tissue by 35%. After an i.v. injection of 0.1 to 0.5 mg flumazenil a decrease of 29 to 38% is observed within 20 min, with a comparable decrease in white matter and nasal tissue. The application of well-known models of receptor kinetics is therefore impossible. Topics: Flumazenil; Hepatic Encephalopathy; Humans; Iodine Radioisotopes; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1992 |