ro-16-0154 has been researched along with Cerebellar-Ataxia* in 2 studies
2 other study(ies) available for ro-16-0154 and Cerebellar-Ataxia
Article | Year |
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Experience of (123)I-iomazenil SPECT study for crossed cerebellocerebral diaschisis: report of two cases.
Topics: Aged; Cerebellar Ataxia; Cerebellar Diseases; Cerebral Angiography; Flumazenil; Headache; Humans; Magnetic Resonance Imaging; Male; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2012 |
Single-photon emission computed tomography image of benzodiazepine receptors in a patient with Creutzfeldt-Jakob disease.
A 50-year-old woman presented with progressive visual disturbance, ataxia, and dementia. The cerebral cortex became atrophic, as the disease progressed, and electroencephalography showed periodic synchronous discharges. The patient's prion gene revealed a point mutation (232Met to Arg), and a diagnosis of Creutzfeldt-Jakob disease was made. Iomazenil single-photon emission computed tomography (SPECT) was performed to assess neuronal degeneration. Accumulation of the tracer in the late images was severely decreased diffusely spread throughout the cerebral cortex. Our experience with this case suggests that iomazenil SPECT is useful for detecting neuronal degeneration in Creutzfeldt-Jakob disease. Topics: Brain; Brain Chemistry; Cerebellar Ataxia; Creutzfeldt-Jakob Syndrome; Female; Flumazenil; Humans; Middle Aged; Myoclonus; Nerve Degeneration; Nerve Tissue Proteins; Point Mutation; PrPC Proteins; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1998 |