ro-16-0154 and Carotid-Artery-Diseases

Many studies of external-internal carotid artery (EC-IC) bypass as cerebral revascularization for unclippable internal carotid artery (ICA) aneurysms have reported surgical outcomes, including bypass patency and aneurysm resolution. However, no previous studies have assessed the long-term outcomes of cerebral blood flow (CBF), brain neural density, and cognition. The purpose of the present study was to evaluate the long-term outcomes of CBF and neurotransmitter receptor function using early and late images of iodine-123 (. We performed a prospective observational study of 11 patients who had undergone superficial temporal artery-middle cerebral artery bypass or bypass using a saphenous vein graft for symptomatic aneurysms in the cavernous portion of the ICA. One patient experienced extensive infarction and, therefore, did not undergo postoperative testing.. None of 10 patients who had undergone EC-IC bypass showed reductions in CBF and brain neural density. In addition, the neuropsychological test scores had not changed significantly from preoperatively to postoperatively.. Using early and late

Topics: Aged; Aged, 80 and over; Brain; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Revascularization; Cerebrovascular Circulation; Cognition; Female; Flumazenil; Humans; Intracranial Aneurysm; Longitudinal Studies; Middle Aged; Middle Cerebral Artery; Prospective Studies; Receptors, GABA-A; Saphenous Vein; Temporal Arteries; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vascular Grafting