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ro 15-4513 and Pain

ro 15-4513 has been researched along with Pain in 1 studies

Ro 15-4513: a partial inverse agonist of benzodiazepine receptors

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
" doses of the full benzodiazepine inverse agonist beta-CCE immediately following cessation of exposure of rats to an anesthetic concentration of methoxyflurane significantly antagonized the duration of methoxyflurane anesthesia as measured by recovery of the righting reflex and/or pain sensitivity."7.67Antagonism of methoxyflurane-induced anesthesia in rats by benzodiazepine inverse agonists. ( Miller, DW; Tessel, RE; Yourick, DL, 1989)
" doses of the full benzodiazepine inverse agonist beta-CCE immediately following cessation of exposure of rats to an anesthetic concentration of methoxyflurane significantly antagonized the duration of methoxyflurane anesthesia as measured by recovery of the righting reflex and/or pain sensitivity."3.67Antagonism of methoxyflurane-induced anesthesia in rats by benzodiazepine inverse agonists. ( Miller, DW; Tessel, RE; Yourick, DL, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, DW1
Yourick, DL1
Tessel, RE1

Other Studies

1 other study available for ro 15-4513 and Pain

ArticleYear
Antagonism of methoxyflurane-induced anesthesia in rats by benzodiazepine inverse agonists.
    European journal of pharmacology, 1989, Nov-28, Volume: 173, Issue:1

    Topics: Anesthesia; Animals; Azides; Benzodiazepines; Carbolines; Electric Stimulation; Ketamine; Male; Meth

1989