ro-13-6298 has been researched along with Body-Weight* in 1 studies
1 other study(ies) available for ro-13-6298 and Body-Weight
Article | Year |
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The effects of arotinoids on rat mammary carcinogenesis.
The influence of two retinoids, Ro 13-6298, an arotinoid ethyl ester, and Ro 15-1570, an arotinoid ethyl sulfone, on rat mammary carcinogenesis was investigated. Mammary carcinomas were induced by oral administration of 15 mg dimethylbenz(a)anthracene (DMBA) to 50-day-old female Sprague-Dawley rats. Oral administration of the two retinoids significantly inhibited the development of tumors. The number and volume of mammary neoplasms were influenced in a dose-dependent manner. Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benzoates; Body Weight; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinoids | 1985 |