rizatriptan and Pain
rizatriptan has been researched along with Pain in 7 studies
rizatriptan: structure given in first source; RN given refers to benzoate
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " In allodynic patients with moderate-to-severe headache, rizatriptan resulted in greater pain relief compared with ibuprofen." | 5.14 | A comparison of migraine patients with and without allodynic symptoms. ( Kalita, J; Misra, UK; Yadav, RK, 2009) |
| "For many migraine patients, triptan therapy provides complete pain relief in some attacks but not in others." | 1.32 | Defeating migraine pain with triptans: a race against the development of cutaneous allodynia. ( Burstein, R; Collins, B; Jakubowski, M, 2004) |
| "Rizatriptan therefore has central activity which may contribute to its efficacy against migraine headache." | 1.30 | Rizatriptan has central antinociceptive effects against durally evoked responses. ( Cumberbatch, MJ; Hargreaves, RJ; Hill, RG, 1997) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Su, M | 1 |
| Ran, Y | 1 |
| Han, X | 1 |
| Liu, Y | 1 |
| Zhang, X | 1 |
| Tan, Q | 1 |
| Li, R | 1 |
| Yu, S | 2 |
| Kalita, J | 1 |
| Yadav, RK | 1 |
| Misra, UK | 1 |
| Dong, Z | 1 |
| Jiang, L | 1 |
| Wang, X | 2 |
| Burstein, R | 1 |
| Collins, B | 1 |
| Jakubowski, M | 1 |
| Iizuka, T | 1 |
| Sakai, F | 1 |
| Tfelt-Hansen, P | 1 |
| Cumberbatch, MJ | 1 |
| Hill, RG | 1 |
| Hargreaves, RJ | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838] | Phase 2 | 40 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
1 review available for rizatriptan and Pain
| Article | Year |
|---|---|
[Recent progress in therapy for migraine headache].
Topics: Anticonvulsants; Botulinum Toxins; Calcitonin Gene-Related Peptide; Central Nervous System; Clinical | 2004 |
Trials
2 trials available for rizatriptan and Pain
| Article | Year |
|---|---|
A comparison of migraine patients with and without allodynic symptoms.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Asian People; Double-Blind Method; Femal | 2009 |
Meta-analysis of oral triptans.
Topics: Administration, Oral; Clinical Trials as Topic; Humans; Indoles; Meta-Analysis as Topic; Pain; Pyrro | 2004 |
Other Studies
4 other studies available for rizatriptan and Pain
| Article | Year |
|---|---|
Rizatriptan overuse promotes hyperalgesia induced by dural inflammatory stimulation in rats by modulation of the serotonin system.
Topics: Animals; Cerebral Cortex; Headache Disorders, Secondary; Hyperalgesia; Inflammation; Male; Pain; Rat | 2016 |
Nociceptive behaviors were induced by electrical stimulation of the dura mater surrounding the superior sagittal sinus in conscious adult rats and reduced by morphine and rizatriptan benzoate.
Topics: Animals; Disease Models, Animal; Dura Mater; Electric Stimulation; Grooming; Male; Morphine; Narcoti | 2011 |
Defeating migraine pain with triptans: a race against the development of cutaneous allodynia.
Topics: Administration, Oral; Adolescent; Adult; Humans; Injections; Middle Aged; Migraine Disorders; Oxazol | 2004 |
Rizatriptan has central antinociceptive effects against durally evoked responses.
Topics: Action Potentials; Analysis of Variance; Animals; Blood-Brain Barrier; Disease Models, Animal; Dose- | 1997 |